A familiar motif in a new context: The catalytic mechanism of hydroxyisourate hydrolase

Biochemistry

Volumn 42, Issue 22, 2003, Pages 6848-6852

  Raychaudhuri, Aniruddha ^a   Tipton, Peter A ^a  

^a University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SEQUENCE HOMOLOGY;

CATALYSIS; ENZYMES; HYDROLYSIS; PH EFFECTS; SUBSTRATES;

BIOCHEMISTRY;

HYDROLASE; HYDROXYISOURATE HYDROLASE; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDROLYSIS; NONHUMAN; PH; PRIORITY JOURNAL; PROTON TRANSPORT; SEQUENCE HOMOLOGY; STEADY STATE;

AMIDOHYDROLASES; AMINO ACID MOTIFS; AMINO ACID SUBSTITUTION; AZIDES; CATALYSIS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; PROTONS; RECOMBINANT PROTEINS; URACIL;

ESCHERICHIA COLI; GLYCINE MAX;

EID: 0037646897     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034137o     Document Type: Article

References (18)

1. Schubert, K. R. (1986) Annu. Rev. Plant Physiol. 37, 539-574.
2. Ohyama, T., and Kumazawa, K. (1978) Soil Sci. Plant Nutr. 24, 525-533.
3. Schubert, K. R. (1981) Plant Physiol. 68, 1115-1122.
4. Modric, N., Derome, A. E., Ashcroft, S. J. H., and Poje, M. (1992) Tetrahedron Lett. 33, 6691-6694.
5. Kahn, K., Serfozo, P., and Tipton, P. A. (1997) J. Am. Chem. Soc. 119, 5435-5442.
6. Sarma, A. D., Serfozo, P., Kahn, K., and Tipton, P. A. (1999) J. Biol. Chem. 274 (48), 33863-33865.
7. Raychaudhuri, A., and Tipton, P. A. (2002) Plant Physiol. 130, 2061-2068.
8. Coutinho, P. M., and Henrissat, B. (1999) in Recent Advances in Carbohydrate Bioengineering (Gilbert, H. J., Davies, G., Henrissat, B., and Svensson, B., Eds.), pp 3-12, The Royal Society of Chemistry, Cambridge.
9. Pfleiderer, W. (1971) Justus Liebigs Ann. Chem. 747, 111-122.
10. Davies, G. J., Mackenzie, L., Varrot, A., Dauter, M., Brzozowski, A. M., Schulein, M., and Withers, S. G. (1998) Biochemistry 37 (34), 11707-11713.
11. Hyland, L. J., Tomaszek, T. A., Roberts, G. D., Carr, S. A., Magaard, V. W., Bryan, H. L., Fakhoury, S. A., Moore, M. L., Minnich, M. D., Cult, J. S., DesJarlais, R. L., and Meek, T. D. (1991) Biochemistry 30, 8441-8453.
12. Joshi, M. D., Sidhu, G., Nielsen, J. E., Brayer, G. D., Withers, S. G., and McIntosh, L. P. (2001) Biochemistry 40, 10115-10139.
13. Kempton, J. B., and Withers, S. G. (1992) Biochemistry 31, 9961-9969.
14. Cleland, W. W. (1982) Methods Enzymol. 87, 390-405.
15. Fersht, A. (1985) Enzyme Structure and Mechanism, W. H. Freeman and Co., New York.
16. Zechel, D. I., and Withers, S. G. (2000) Acc. Chem. Res. 33, 11-18.
17. Ly, H. D., and Withers, S. G. (1999) Annu. Rev. Biochem. 68, 487-522.
18. Thoden, J. B., Phillips, G. N., Jr., Neal, T. M., Raushel, F. M., and Holden, H. M. (2001) Biochemistry 40 (24), 6989-6997.