Striking and rapid improvement of plaque psoriasis with infliximab: A report of two cases

Dermatology

Volumn 207, Issue 1, 2003, Pages 54-56

  Al Salem, Iqbal Hamad ^a,b  

^a AL AMIRI HOSPITAL   (Kuwait)

^b NONE   (Kuwait)

Author keywords

Pathogenesis; Proinflammatory cytokine; Tumor necrosis factor

Indexed keywords

CORTICOSTEROID DERIVATIVE; INFLIXIMAB; METHOTREXATE; SALICYLIC ACID; TAR;

ADULT; ARTICLE; BODY WEIGHT; CASE REPORT; CLINICAL EXAMINATION; CLINICAL PROTOCOL; DISEASE SEVERITY; DRUG INFUSION; GASTROINTESTINAL SYMPTOM; GOOD GENERAL CONDITION; HUMAN; HYPERKERATOSIS; LABORATORY TEST; MALE; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PSORIASIS VULGARIS; PSORIATIC ARTHRITIS; SIDE EFFECT; SKIN DEFECT; SYMPTOM; SYNOVITIS; TREATMENT OUTCOME; TREATMENT PLANNING;

ADULT; ANTIBODIES, MONOCLONAL; DERMATOLOGIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FOLLOW-UP STUDIES; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; PSORIASIS; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 0037634484     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000071685     Document Type: Article

References (6)

1. Ettehadi P, Greaves MW, Wallah D, et al: Elevated tumor necrosis factor-alpha biological activity in psoriatic skin lesions. Clin Exp Immunol 1994;96:146-151.
2. Hunter JAA, Savin JA, Dahl MV (eds): Clinical Dermatology, ed 2. Oxford, Blackwell Science, 1995, p 53.
3. Tan MH, Gordon M, Lebwohl O, George J, Lebwohl MG: Improvement of pyoderma gangrenosum and psoriasis associated with Crohn's disease with antitumor necrosis factor monoclonal antibody. Arch Dermatol 2001; 137:930-933.
4. Ogilvie ALJ, Antoni C, Dechant C, Manger B, Kalden JR, Schulter G, Lufti M: Treatment of psoriatic arthritis with antitumor necrosis factor alpha antibody clears skin lesions of psoriasis resistant to treatment with methotrexate. Br J Dermatol 2001;144:587-589.
5. Chaudhari U, Romano P, Mulcahy LD, Dooley LT, Baker DJ, Gottlieb AB: Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: A randomized trial. Lancet 2001;357:1842-1847.
6. Grange F, Djilali-Bouzina F, Weiss AM, Polette A, Guillaume JC: Corticosteroid-resistant pyoderma gangrenosum associated with Crohn's disease: Rapid cure with infliximab. Dermatology 2002;205:278-280.