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Volumn 14, Issue 6, 2003, Pages 2543-2558

Nuclear export and plasma membrane recruitment of the Ste5 scaffold are coordinated with oligomerization and association with signal transduction components

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DNA; GUANINE NUCLEOTIDE BINDING PROTEIN; LEUCINE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN; STE5 SCAFFOLD; UNCLASSIFIED DRUG;

EID: 0037632831     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-10-0699     Document Type: Article
Times cited : (33)

References (46)
  • 1
    • 0025897247 scopus 로고
    • Rapid colony transformation of Saccharomyces cerevisiae
    • Baker, R. (1991). Rapid colony transformation of Saccharomyces cerevisiae. Nucleic Acids Res. 19, 1945
    • (1991) Nucleic Acids Res. , vol.19 , pp. 1945
    • Baker, R.1
  • 2
    • 0034602928 scopus 로고    scopus 로고
    • RING domains: Master builders of molecular scaffolds?
    • Borden, K.L.B. (2000). RING domains: master builders of molecular scaffolds? J. Mol. Biol. 295, 1103-1112.
    • (2000) J. Mol. Biol. , vol.295 , pp. 1103-1112
    • Borden, K.L.B.1
  • 3
    • 0037085259 scopus 로고    scopus 로고
    • Phosphorylation regulates the nucleocytoplasmic distribution of kinase suppressor of Ras
    • Brennan, J.A., Volle, D.J., Chaika, O.V., and Lewis, R.E. (2002). Phosphorylation regulates the nucleocytoplasmic distribution of kinase suppressor of Ras. J. Biol. Chem. 277, 5369-5377.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5369-5377
    • Brennan, J.A.1    Volle, D.J.2    Chaika, O.V.3    Lewis, R.E.4
  • 4
    • 0034009390 scopus 로고    scopus 로고
    • Signal transduction: Hanging on a scaffold
    • Burack, W.R., and Shaw, A.S. (2000). Signal transduction: hanging on a scaffold. Curr. Opin. Cell Biol. 12, 211-216.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 211-216
    • Burack, W.R.1    Shaw, A.S.2
  • 5
    • 0032896036 scopus 로고    scopus 로고
    • Characterization of Fus3 localization, Active Fus3 localizes in complexes of varying size and specific activity
    • Choi, K.-Y., Kranz, J.A., Mahanty, S.K., and Elion, E.A. (1999). Characterization of Fus3 localization, Active Fus3 localizes in complexes of varying size and specific activity. Mol. Biol. Cell 10, 1553-1568.
    • (1999) Mol. Biol. Cell. , vol.10 , pp. 1553-1568
    • Choi, K.-Y.1    Kranz, J.A.2    Mahanty, S.K.3    Elion, E.A.4
  • 6
    • 0027983908 scopus 로고
    • Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae
    • Choi, K.-Y., Satterberg, B., Lyons, D.M., and Elion, E.A. (1994). Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae. Cell 78, 499-512.
    • (1994) Cell , vol.78 , pp. 499-512
    • Choi, K.-Y.1    Satterberg, B.2    Lyons, D.M.3    Elion, E.A.4
  • 7
    • 0029092222 scopus 로고
    • A role for the Gal11 protein in pheromone-induced transcription in Saccharomyces cerevisiae
    • Dolan, J.W., and Gatlin, J.E. (1995). A role for the Gal11 protein in pheromone-induced transcription in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 212, 854-860.
    • (1995) Biochem. Biophys. Res. Commun. , vol.212 , pp. 854-860
    • Dolan, J.W.1    Gatlin, J.E.2
  • 8
    • 0029012079 scopus 로고
    • Ste5, a meeting place for MAP kinases and their associates
    • Elion, E.A. (1995). Ste5, a meeting place for MAP kinases and their associates. Trends Cell Biol. 5, 322-327.
    • (1995) Trends Cell Biol. , vol.5 , pp. 322-327
    • Elion, E.A.1
  • 9
    • 0035195491 scopus 로고    scopus 로고
    • The Ste5 Scaffold
    • Elion, E.A. (2001). The Ste5 Scaffold. J. Cell Sci. 114, 3967-3978.
    • (2001) J. Cell Sci. , vol.114 , pp. 3967-3978
    • Elion, E.A.1
  • 11
    • 0025101239 scopus 로고
    • FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation
    • Elion, E.A., Grisafi, P.L., and Fink, G.R. (1990). FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation. Cell 60, 649-664.
    • (1990) Cell , vol.60 , pp. 649-664
    • Elion, E.A.1    Grisafi, P.L.2    Fink, G.R.3
  • 12
    • 0027253814 scopus 로고
    • FUS3 phosphorylates multiple components of the mating signal transduction cascade. Evidence for STE12 and FAR1
    • Elion, E.A., Satterberg, B., and Kranz, J.E. (1993). FUS3 phosphorylates multiple components of the mating signal transduction cascade. Evidence for STE12 and FAR1. Mol. Biol. Cell 4, 495-510.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 495-510
    • Elion, E.A.1    Satterberg, B.2    Kranz, J.E.3
  • 13
    • 0027476416 scopus 로고
    • MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro
    • Errede, B., Gartner, A., Zhou, Z., Nasmyth, K., and Ammerer, G. (1993). MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro. Nature 362, 261-264.
    • (1993) Nature , vol.362 , pp. 261-264
    • Errede, B.1    Gartner, A.2    Zhou, Z.3    Nasmyth, K.4    Ammerer, G.5
  • 14
    • 0032920977 scopus 로고    scopus 로고
    • Relative dependence of different outputs of the Saccharomyces cerevisiae pheromone response pathway on the MAP kinase Fus3p
    • Farley, F.W., Satterberg, B., Goldsmith, E.J., and Elion, E.A. (1999). Relative dependence of different outputs of the Saccharomyces cerevisiae pheromone response pathway on the MAP kinase Fus3p. Genetics 151, 1425-1444.
    • (1999) Genetics , vol.151 , pp. 1425-1444
    • Farley, F.W.1    Satterberg, B.2    Goldsmith, E.J.3    Elion, E.A.4
  • 15
    • 0032567815 scopus 로고    scopus 로고
    • Functional binding between Gβ and the LIM domain of Ste5 is required to activate the MEKK Ste11
    • Feng, Y., Song, L., Kincaid, E., Mahanty, S.K., and Elion, E.A. (1998). Functional binding between Gβ and the LIM domain of Ste5 is required to activate the MEKK Ste11. Curr. Biol. 8, 267-278.
    • (1998) Curr. Biol. , vol.8 , pp. 267-278
    • Feng, Y.1    Song, L.2    Kincaid, E.3    Mahanty, S.K.4    Elion, E.A.5
  • 18
    • 0030777328 scopus 로고    scopus 로고
    • Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: Application of a differential interaction trap assay for examining protein-protein interactions
    • Inouye, C., Dhillon, N., and Thorner, J. (1997b). Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: application of a differential interaction trap assay for examining protein-protein interactions. Genetics 147, 479-492.
    • (1997) Genetics , vol.147 , pp. 479-492
    • Inouye, C.1    Dhillon, N.2    Thorner, J.3
  • 19
    • 0030815533 scopus 로고    scopus 로고
    • Ste5 RING-H2 domain-Role in Ste4-promoted oligomerization for yeast pheromone signaling
    • Inouye, C., Dhillon, N., and Thorner, J. (1997a). Ste5 RING-H2 domain-Role in Ste4-promoted oligomerization for yeast pheromone signaling. Science 278, 103-106.
    • (1997) Science , vol.278 , pp. 103-106
    • Inouye, C.1    Dhillon, N.2    Thorner, J.3
  • 20
    • 0034635502 scopus 로고    scopus 로고
    • Formation of the Ras dimer is essential for Raf-1 activation
    • Inouye, K., Mizutani, S., Koide, H., and Kaziro, Y. (2000). Formation of the Ras dimer is essential for Raf-1 activation. J. Biol. Chem. 275, 3737-3740.
    • (2000) J. Biol. Chem. , vol.275 , pp. 3737-3740
    • Inouye, K.1    Mizutani, S.2    Koide, H.3    Kaziro, Y.4
  • 21
    • 0343852701 scopus 로고    scopus 로고
    • Conformational stability of pGEX-expressed Schistosoma japonicum glutathione S-transferase, a detoxification enzyme and fusion protein affinity tag
    • Kaplan, W., Husler, P., Klump, H., Erhardt, J., Sluiscremer, N., and Dirr, H. (1997). Conformational stability of pGEX-expressed Schistosoma japonicum glutathione S-transferase, a detoxification enzyme and fusion protein affinity tag. Protein Sci. 6, 399-406.
    • (1997) Protein Sci. , vol.6 , pp. 399-406
    • Kaplan, W.1    Husler, P.2    Klump, H.3    Erhardt, J.4    Sluiscremer, N.5    Dirr, H.6
  • 23
    • 0028057744 scopus 로고
    • The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5
    • Kranz, J., Satterberg, B., and Elion, E.A. (1994). The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5. Genes Dev. 8, 313-327.
    • (1994) Genes Dev. , vol.8 , pp. 313-327
    • Kranz, J.1    Satterberg, B.2    Elion, E.A.3
  • 24
    • 0036240658 scopus 로고    scopus 로고
    • Cdc42 regulation of kinase activity and signaling by the yeast p21-activated kinase Ste20
    • Lamson, R.E., Winters, M.J., and Pryciak, P.M. (2002). Cdc42 regulation of kinase activity and signaling by the yeast p21-activated kinase Ste20. Mol. Cell. Biol. 22, 2932-2951.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2932-2951
    • Lamson, R.E.1    Winters, M.J.2    Pryciak, P.M.3
  • 25
    • 2542586045 scopus 로고    scopus 로고
    • The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components
    • Lee, B., and Elion, E.A. (1999). The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components. Proc. Natl. Acad. Sci. USA 96, 12679-12684.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 12679-12684
    • Lee, B.1    Elion, E.A.2
  • 26
    • 0032495478 scopus 로고    scopus 로고
    • Interaction of a G-protein β-subunit with a conserved sequence in Ste20/PAK family protein kinases
    • Leeuw, T., Wu, C.L., Schrag, J.D., Whiteway, M., Thomas, D.Y., and Leberer, E. (1998). Interaction of a G-protein β-subunit with a conserved sequence in Ste20/PAK family protein kinases. Nature 391, 191-195.
    • (1998) Nature , vol.391 , pp. 191-195
    • Leeuw, T.1    Wu, C.L.2    Schrag, J.D.3    Whiteway, M.4    Thomas, D.Y.5    Leberer, E.6
  • 27
    • 0033588242 scopus 로고    scopus 로고
    • Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade
    • Mahanty, S.K., Wang, Y., Farley, F.W., and Elion, E.A. (1999). Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade. Cell 98, 501-512.
    • (1999) Cell , vol.98 , pp. 501-512
    • Mahanty, S.K.1    Wang, Y.2    Farley, F.W.3    Elion, E.A.4
  • 28
    • 0029945421 scopus 로고    scopus 로고
    • The dimerization property of glutathione S-transferase partially reactivates Bcr-Abl lacking the oligomerization domain
    • Maru, Y., Afar, D.E.., Witte, O.N., and Shibuya, M. (1996). The dimerization property of glutathione S-transferase partially reactivates Bcr-Abl lacking the oligomerization domain. J. Biol. Chem. 271, 15353-15357.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15353-15357
    • Maru, Y.1    Afar, D.E.2    Witte, O.N.3    Shibuya, M.4
  • 29
    • 0028931691 scopus 로고
    • Crystal structures of a schistosomal drug and vaccine target: Glutathione S-transferase from Schistosoma japonicum and its complex with the leading antischistosomal drug praziquantel
    • McTigue, M.A., Williams, D.R., and Tainer, J.A. (1995). Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonicum and its complex with the leading antischistosomal drug praziquantel. J. Mol. Biol. 246, 21-27.
    • (1995) J. Mol. Biol. , vol.246 , pp. 21-27
    • McTigue, M.A.1    Williams, D.R.2    Tainer, J.A.3
  • 30
    • 0033801741 scopus 로고    scopus 로고
    • Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae
    • Moskow, J.J., Gladfelter, A.S., Lamson, R.E., Pryciak, P.M., and Lew, D.J. (2000). Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae. Mol. Cell. Biol. 20, 7559-7571.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7559-7571
    • Moskow, J.J.1    Gladfelter, A.S.2    Lamson, R.E.3    Pryciak, P.M.4    Lew, D.J.5
  • 31
    • 0027429634 scopus 로고
    • Analysis of nucleocytoplasmic transport in a thermosensitive mutant of nuclear pore protein NSP1
    • Nehrbass, U., Fabre, E., Dihlmann, S., Herth, W., and Hurt, E.C. (1993). Analysis of nucleocytoplasmic transport in a thermosensitive mutant of nuclear pore protein NSP1. Eur. J. Cell Biol. 62, 1-12.
    • (1993) Eur. J. Cell Biol. , vol.62 , pp. 1-12
    • Nehrbass, U.1    Fabre, E.2    Dihlmann, S.3    Herth, W.4    Hurt, E.C.5
  • 32
    • 0028261404 scopus 로고
    • Reconstitution of a yeast protein kinase cascade in vitro: Activation of the yeast MEK homologue STE7 by STE11
    • Neiman, A.M., and Herskowitz, I. (1994). Reconstitution of a yeast protein kinase cascade in vitro: activation of the yeast MEK homologue STE7 by STE11. Proc. Natl. Acad. Sci. USA 91, 3398-3402.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3398-3402
    • Neiman, A.M.1    Herskowitz, I.2
  • 33
    • 0036239642 scopus 로고    scopus 로고
    • Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo
    • Nguyen, A., et al. (2002). Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo. Mol. Cell. Biol. 22, 3035-3045.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 3035-3045
    • Nguyen, A.1
  • 34
    • 0031457622 scopus 로고    scopus 로고
    • Signaling through scaffold, anchoring, and adaptor proteins
    • Pawson, T., and Scott, J.D. (1997). Signaling through scaffold, anchoring, and adaptor proteins. Science 278, 2075-2080.
    • (1997) Science , vol.278 , pp. 2075-2080
    • Pawson, T.1    Scott, J.D.2
  • 35
    • 0032168881 scopus 로고    scopus 로고
    • Membrane recruitment of the kinase cascade scaffold protein Ste5 by the G-βγ complex underlies activation of the yeast pheromone response pathway
    • Pryciak, P.M., and Huntress, F.A. (1998). Membrane recruitment of the kinase cascade scaffold protein Ste5 by the G-βγ complex underlies activation of the yeast pheromone response pathway. Genes Dev. 12, 2684-2697.
    • (1998) Genes Dev. , vol.12 , pp. 2684-2697
    • Pryciak, P.M.1    Huntress, F.A.2
  • 37
    • 0030795544 scopus 로고    scopus 로고
    • Importin/karyopherin protein family members required for mRNA export from the nucleus
    • Seedorf, M., and Silver, P.A. (1997). Importin/karyopherin protein family members required for mRNA export from the nucleus. Proc. Natl. Acad. Sci. USA 94, 8590-8595.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8590-8595
    • Seedorf, M.1    Silver, P.A.2
  • 38
    • 0033739255 scopus 로고    scopus 로고
    • Mutational analysis suggests that activation of the yeast pheromone response MAPK pathway involves conformational changes in the Ste5 scaffold protein
    • Sette, C., Inouye, C.J., Stroschein, S.L., Iaquinta, P.J., and Thorner, J. (2000). Mutational analysis suggests that activation of the yeast pheromone response MAPK pathway involves conformational changes in the Ste5 scaffold protein. Mol. Biol. Cell 11, 4033-4049.
    • (2000) Mol. Biol. Cell. , vol.11 , pp. 4033-4049
    • Sette, C.1    Inouye, C.J.2    Stroschein, S.L.3    Iaquinta, P.J.4    Thorner, J.5
  • 39
    • 0026774153 scopus 로고
    • Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein
    • Stevenson, B.J., Rhodes, N., Errede, B., and Sprague, G.F., Jr. (1992). Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein. Genes Dev. 6, 1293-1304.
    • (1992) Genes Dev. , vol.6 , pp. 1293-1304
    • Stevenson, B.J.1    Rhodes, N.2    Errede, B.3    Sprague G.F., Jr.4
  • 40
    • 0030842771 scopus 로고    scopus 로고
    • Glutathione S-transferase can be used as an enzymatically active dimerization module for a recombinant protease inhibitor, and functionally secreted into the periplasm of Escherichia coli
    • Tudyka, T., and Skerra, A. (1997). Glutathione S-transferase can be used as an enzymatically active dimerization module for a recombinant protease inhibitor, and functionally secreted into the periplasm of Escherichia coli. Protein Sci. 6, 2180-2187.
    • (1997) Protein Sci. , vol.6 , pp. 2180-2187
    • Tudyka, T.1    Skerra, A.2
  • 41
    • 0034213955 scopus 로고    scopus 로고
    • Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signaling in vivo
    • van Drogen, F., O'Rourke, S.M., Stucke, V.M., Jaquenoud, M., Neiman, A.M., and Peter, M. (2000). Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signaling in vivo. Curr. Biol. 10, 630-639.
    • (2000) Curr. Biol. , vol.10 , pp. 630-639
    • Van Drogen, F.1    O'Rourke, S.M.2    Stucke, V.M.3    Jaquenoud, M.4    Neiman, A.M.5    Peter, M.6
  • 42
    • 0035203511 scopus 로고    scopus 로고
    • MAP kinase dynamics in response to pheromones in budding yeast
    • van Drogen, F., Stucke, V.M., Jorritsma, G., and Peter, M. (2001). MAP kinase dynamics in response to pheromones in budding yeast. Nat. Cell Biol. 3, 1051-1059.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 1051-1059
    • Van Drogen, F.1    Stucke, V.M.2    Jorritsma, G.3    Peter, M.4
  • 43
    • 0029146796 scopus 로고
    • Association of the yeast pheromone response G protein βγ subunits with the MAP kinase scaffold Ste5p
    • Whiteway, M.S., Wu, C., Leeuw, T., Clark, K., Fourest-Lieuvin, A., Thomas, D.Y., and Leberer, E. (1995). Association of the yeast pheromone response G protein βγ subunits with the MAP kinase scaffold Ste5p. Science 269, 1572-1575.
    • (1995) Science , vol.269 , pp. 1572-1575
    • Whiteway, M.S.1    Wu, C.2    Leeuw, T.3    Clark, K.4    Fourest-Lieuvin, A.5    Thomas, D.Y.6    Leberer, E.7
  • 44
    • 0029066439 scopus 로고
    • Molecular characterization of Ste20p, a potential mitogen-activated protein or extracellular signal-regulated kinase kinase (MEK) kinase kinase from Saccharomyces cerevisiae
    • Wu, C., Whiteway, M., Thomas, D.Y., and Leberer, E. (1995). Molecular characterization of Ste20p, a potential mitogen-activated protein or extracellular signal-regulated kinase kinase (MEK) kinase kinase from Saccharomyces cerevisiae. J. Biol. Chem. 270, 15984-15992.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15984-15992
    • Wu, C.1    Whiteway, M.2    Thomas, D.Y.3    Leberer, E.4
  • 45
    • 0030450397 scopus 로고    scopus 로고
    • Dimerization of Ste5, a mitogen-activated protein kinase cascade scaffold protein, is required for signal transduction
    • Yablonski, D., Marbach, I., and Levitzki, A. (1996). Dimerization of Ste5, a mitogen-activated protein kinase cascade scaffold protein, is required for signal transduction. Proc. Natl. Acad. Sci. USA 93, 13864-13869.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13864-13869
    • Yablonski, D.1    Marbach, I.2    Levitzki, A.3
  • 46


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