Stability and preservative effectiveness of treprostinil sodium after dilution in common intravenous diluents

American Journal of Health-System Pharmacy

Volumn 60, Issue 9, 2003, Pages 916-922

  Phares, Kenneth R ^a,c   Weiser, William E ^b   Miller, Stephen P ^b   Myers, Melissa A ^b   Wade, Michael ^b  

^a Dept of Pharmaceutical Development   (United States)

^b Magellan Pharmaceutical Devmt   (United States)

^c UNITED THERAPEUTICS CORPORATION   (United States)

Author keywords

Concentration; Contamination; Dextrose; Diluents; Hydrogen ion concentration; Hypotensive agents; Injections; Metacresol; Preservatives; Sodium chloride; Stability; Storage; Treprostinil sodium; Water for injection

Indexed keywords

ANTIHYPERTENSIVE AGENT; DILUENT; GLUCOSE; META CRESOL; PRESERVATIVE; SODIUM CHLORIDE; UNIPROST; WATER;

ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; CANDIDA ALBICANS; DILUTION; DRUG DEGRADATION; DRUG DETERMINATION; DRUG STABILITY; DRUG STORAGE; ESCHERICHIA COLI; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMIDITY; INOCULATION; PARTICULATE MATTER; PH; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; TEMPERATURE;

EID: 0037632757     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajhp/60.9.916     Document Type: Article

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