Defective sorting to secretory vesicles in trans-Golgi network is partly responsible for protein C deficiency: Molecular mechanisms of impaired secretion of abnormal protein C R169W, R352W, and G376D

Circulation Research

Volumn 92, Issue 8, 2003, Pages 865-872

  Naito, Masao ^a   Mimuro, Jun ^a   Endo, Hitoshi ^a   Madoiwa, Seiji ^a   Ogata, Kyo ichi ^a   Kikuchi, Jiro ^a   Sugo, Teruko ^a   Yasu, Takanori ^a   Kariya, Yusei ^a   Hoshino, Yuichi ^a   Sakata, Yoichi ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Intracellular protein transport; Protein C deficiency; Thrombosis

Indexed keywords

MUTANT PROTEIN; PROTEIN C; VITAMIN K GROUP;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; GOLGI COMPLEX; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN C DEFICIENCY; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN TARGETING; SECRETORY VESICLE;

ANIMALS; ANTIBODIES, MONOCLONAL; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CHO CELLS; CRICETINAE; CULTURE MEDIA, CONDITIONED; GLYCOSYLATION; GOLGI APPARATUS; HUMANS; MICROSCOPY, CONFOCAL; MUTATION; MUTATION, MISSENSE; PLASMIDS; PROTEIN C; RECOMBINANT PROTEINS; SECRETORY VESICLES; THROMBOPHILIA; TRANSFECTION;

EID: 0037630008     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000069020.87627.7D     Document Type: Article

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