A possible mechanism of gastrointestinal toxicity posed by mycophenolic acid

Pharmacological Research

Volumn 47, Issue 6, 2003, Pages 523-526

  Neerman, Michael F ^a   Boothe, Dawn M ^b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Inosine monophosphate dehydrogenase (IMPDH); Mycophenolate mofetil (MMF); Mycophenolic acid (MPA)

Indexed keywords

ANTIDIARRHEAL AGENT; CYTOKINE; DNA; DRUG METABOLITE; GAMMA INTERFERON; GLUCURONIDE; GUANOSINE PHOSPHATE; IMMUNOGLOBULIN; IMMUNOSUPPRESSIVE AGENT; INOSINATE DEHYDROGENASE; INOSINATE DEHYDROGENASE INHIBITOR; INOSINE PHOSPHATE; INTERLEUKIN 2; ISOENZYME; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; MYCOPHENOLIC ACID BETA D GLUCURONIDE; PHOSPHATE; PRODRUG; PURINE NUCLEOTIDE; UNCLASSIFIED DRUG; XANTHINE MONOPHOSPHATE;

ABDOMINAL CRAMP; ANEMIA; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; B LYMPHOCYTE; BLOOD TOXICITY; CELL SIZE; CELL TYPE; CLINICAL TRIAL; CYTOKINE PRODUCTION; DIARRHEA; DIGESTIVE SYSTEM ULCER; DNA CONTENT; DNA SYNTHESIS; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG ELIMINATION; DRUG EXCRETION; DRUG FATALITY; DRUG GLUCURONIDATION; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG MECHANISM; DRUG SELECTIVITY; DRUG TARGETING; ENZYME INHIBITION; ESOPHAGITIS; GASTRITIS; GASTROINTESTINAL MUCOSA; GASTROINTESTINAL TOXICITY; HUMAN; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY ALLOGRAFT REJECTION; KIDNEY TRANSPLANTATION; LYMPHOCYTE PROLIFERATION; NAUSEA; NONHUMAN; NUCLEOTIDE METABOLISM; OPPORTUNISTIC INFECTION; PRIORITY JOURNAL; REVIEW; SINGLE DRUG DOSE; T LYMPHOCYTE ACTIVATION; UPREGULATION; VOMITING; YEAST CELL;

EID: 0037624810     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-6618(03)00055-0     Document Type: Review

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