Pleckstrin homology domain of G protein-coupled receptor kinase-2 blinds to PKC and affects the activity of PKC kinase

World Journal of Gastroenterology

Volumn 9, Issue 4, 2003, Pages 800-803

  Yang, Xing Long ^a   Zhang, Ya Li ^a   Lai, Zhuo Sheng ^a   Xing, Fei Yue ^b   Liu, Yu Hu ^a  

^a FIRST MILITARY MEDICAL UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; CELL DNA; G PROTEIN COUPLED RECEPTOR KINASE 2; GLUTATHIONE TRANSFERASE; MESSENGER RNA; PLECKSTRIN; PROTEIN KINASE C; PROTEIN TYROSINE KINASE;

ARTICLE; CELL CULTURE; CELL LINE; CONTROLLED STUDY; DNA SEQUENCE; DOWN REGULATION; ENZYME ACTIVITY; EXPRESSION VECTOR; GENE INSERTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; LONG TERM CARE; PLACENTA; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; UPREGULATION; WESTERN BLOTTING;

EID: 0037624579     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v9.i4.800     Document Type: Article

References (18)

1. Sallese M, Iacovelli L, Cumashi A, Capobianco L, Cuomo L, De Blasi A. Regulation of G protein-coupled receptor kinase subtypes by calcium sensor proteins. Biochim Biophys Acta 2000; 1498: 112-121
2. Diviani D, Lattion AL, Cotecchia S. Characterization of the phosphorylation sites involved in G protein-coupled receptor kinase- and protein kinase C-mediated desensitization of the alpha1B-adrenergic receptor. J Biol Chem 1997; 272: 28712-28719
3. Winstel R, Freund S, Krasel C, Hoppe E, Lohse MJ. Protein kinase cross-talk: Membrane targeting of the beta-adrenergic receptor kinase by protein kinase C. Proc Natl Acad Sci USA 1996; 93: 2105-2109
4. Garcia-Sainz JA, Vazquez-Prado J, Del Carmen Medina L. Alpha 1-adrenoceptors: Function and phosphorylation. Eur J Pharmacol 2000; 389: 1-12
5. Touhara K. Effects of mutations in pleckstrin homology domain on beta-adrenergic receptor kinase activity in intact cells. Biochem-Biophys Res Commun 1998; 252: 669-674
6. Yao L, Kawakami Y, Kawakami T. The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C. Proc Natl Acad Sci USA 1994; 91: 9175-9179
7. Baisden JM, Qian Y, Zot HM, Flynn DC. The actin filment-associated protein AFAP-110 is an adaptor protein that modulates changed in actin filament integrity. Oncogene 2001; 20: 6435-6447
8. Nishizuka Y. The protein kinase C family and lipid mediators for transmembrane signaling and cell regulation. Alcohol Clin Exp Res 2001; 25: 3S-7S
9. Pronin AN, Benovic JL. Regulation of the G protein-coupled receptor kinase GRK5 by protein kinase C. J Biol Chem 1997; 272: 3806-3812
10. Berrada K, Plesnicher CL, Luo X, Thibonnier M. Dynamic interaction of human vasopressin/oxytocin receptor subtypes with G protein-coupled receptor kinases and protein kinase C after agonist stimulation. J Biol Chem 2000; 275: 27229-27237
11. Hosey MM, Benovic JL, DebBurman SK, Richardson RM. Multiple mechanisms involving protein phosphorylation are linked to desensitization of muscarinic receptors. Life Sci 1995; 56: 951-955
12. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987; 162: 156-159
13. Chuang TT, LeVine H 3rd, De Blasi A. Phosphorylation and activation of beta-adrenergic receptor kinase by protein kinase C. J Biol Chem 1995; 270: 18660-18665
14. Chuang TT, Sallese M, Ambrosini G, Parruti G, De Blasi A. High expression of beta-adrenergic receptor kinase in human peripheral blood leukocytes. Isoproterenol and platelet activating factor can induce kinase translocation. J Biol Chem 1992; 267: 6886-6892
15. 2 by protein kinase C abolishes its inhibition by calmodulin. J Biol Chem 2001; 276: 1911-1915
16. Rasmussen H, Isales CM, Calle R, Throckmorton D, Anderson M, Gasalla-Herraiz J, McCarthy R. Diacylglycerol production, Ca2+ influx, and protein kinase C activation in sustained cellular responses. Endocr Rev 1995; 16: 649-681
17. Bruch RC, Kang J, Moore ML Jr, Medler KF. Protein kinase C and receptor kinase gene expression in olfactory receptor neurons. J Neurobiol 1997; 33: 387-394
18. Zheng J, Cahill SM, Lemmon MA, Fushman D, Schlessinger J, Cowburn D. Identification of the binding site for acidic phospholipids on the PH domain of dynamin: Implications for stimulation of GTPase activity. J Mol Biol 1996; 255: 14-21