The histone deacetylase inhibitor, trichostatin A, reactivates the developmentally silenced γ globin expression in somatic cell hybrids and induces γ gene expression in adult BFUe cultures

Blood Cells, Molecules, and Diseases

Volumn 30, Issue 3, 2003, Pages 254-257

  Swank, Richard A ^a,b   Skarpidi, Eva ^a   Papayannopoulou, Thalia ^a   Stamatoyannopoulos, George ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Organon Pharmaceuticals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; GAMMA GLOBIN; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; MESSENGER RNA; TRICHOSTATIN A;

ARTICLE; BURST FORMING UNIT E; CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; FETUS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE LOCUS; GENE SILENCING; GENE SWITCHING; HUMAN; HUMAN CELL; HYBRID CELL; IMMUNOFLUORESCENCE; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SOMATIC CELL; UPREGULATION;

EID: 0037624507     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1079-9796(03)00024-X     Document Type: Article

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