Permeation of cytotoxic formulations through swatches from selected medical gloves

American Journal of Health-System Pharmacy

Volumn 60, Issue 10, 2003, Pages 1006-1011

  Klein, Michael ^a   Lambov, Nikolai ^b   Samev, Nikola ^c   Carstens, Gerhard ^a  

^a St Bernward Apotheke   (Germany)

^b MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^c Sanita   (Bulgaria)

Author keywords

Antineoplastic agents; Carmustine; Gloves; Latex; Neoprene; Penetration; Permeability; Permeation

Indexed keywords

ANTINEOPLASTIC AGENT; BLEOMYCIN SULFATE; BLEOMYCINUM; CARMUSTINE; CYTOTOXIC AGENT; DACARBAZINE; DAUNORUBICIN; DETIMEDAC; ETO CS; ETOPOFOS; ETOPOSIDE; HYCAMTIM; IDARUBICIN; IFO CELL 1000; IFO CELL N 1000; IFOSFAMIDE; IRINOTECAN; LATEX; MITOMYCIN; MITOXANTRONE; NAVELBINE; NEOPRENE; OXALIPLATIN; TENIPOSIDE; TOPOTECAN; WATER;

ARTICLE; DRUG FORMULATION; DRUG PENETRATION; GLOVE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0037616487     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajhp/60.10.1006     Document Type: Article

References (19)

1. Klein M, Rau S, Samev N et al. Protection offered by selected medical gloves made of either latex or a synthetic elastomer against exposure to nine cytotoxic agents. Eur Hosp Pharm. 1999; 5:152-8.
2. Connor TH, Laidlaw JL, Theiss JC et al. Permeability of latex and polyvinyl chloride gloves to carmustine. Am J Hosp Pharm. 1984; 41:676-9.
3. Laidlaw JL, Connor TH, Theiss JC et al. Permeability of latex and polyvinyl chloride gloves to 20 antineoplastic drugs. Am J Hosp Pharm. 1984; 41: 2618-23.
4. Laidlaw JL, Connor TH, Theiss JC et al. Permeability of four disposable protective clothing materials to seven antineoplastic drugs. Am J Hosp Pharm. 1985; 42:2449-54.
5. Thomas PH, Fenton-May V. Protection offered by various gloves to carmustine exposure. Pharm J. 1987; 238:775-7.
6. Corlett SA, Williams AC, Chrystyn H. Permeation of ifosfamide through gloves and cadaver skin. Pharm J. 1991; 274:R39. Letter.
7. Mader RM, Rizovski B, Steger GG et al. Permeability of latex membranes to anticancer drugs. Int J Pharm. 1991; 68:151-6.
8. Dinter-Heidorn H, Carstens G. Comparative study on protective gloves for handling cytotoxic medicines: a model study with carmustine. Pharm Weekbl Sci. 1992; 14:180-4.
9. Connor TH. An evaluation of the permeability of disposable polypropylene-based protective gowns to a battery of cancer chemotherapy drugs. Appl Occup Environ Hyg. 1993; 8:785-9.
10. Connor TH. Permeability testing of glove materials for use with cancer chemotherapy drugs. Oncology. 1995; 52:256-9.
11. European standard EN 374-3, protective clothing-protective gloves against chemicals and micro-organisms; part 3: determination of resistance to permeation by chemicals. Brussels, Belgium: European Committee for Standardization; 1994.
12. Miller JC, Miller JN. Statistics for analytical chemistry. 2nd ed. Chichester, England: Ellis Horwood Limited; 1988:115-7.
13. Benvenuto JA, Connor TH, Monteith DK et al. Degradation and inactivation of antitumor drugs. J Pharm Sci. 1993; 82:988-91.
14. European Standard EN 369, protective clothing - protection against liquid chemicals - test method: resistance of materials to permeation by liquids. Brussels, Belgium: European Committee for Standardization; 1993.
15. Connor TH. Permeability of nitrile rubber, latex, polyurethane, and neoprene gloves to 18 antineoplastic drugs. Am J Health-Syst Pharm. 1999; 56:2450-3.
16. Singleton LC, Connor TH. An evaluation of the permeability of chemotherapy gloves to three cancer chemotherapy drugs. Oncol Nurs Forum. 1999; 26:1491-6.
17. Crank J, Park GS. Diffusion in polymers. New York: Academic Press; 1968:1-39.
18. Sansone EB, Tewari YB. The permeability of laboratory gloves to selected solvents. Am Ind Hyg Assoc J. 1978; 39:169-74.
19. Colligan SA, Horstman SW. Permeation of cancer chemotherapeutic drugs through glove materials under static and flexed conditions. Appl Occup Environ Hyg. 1990; 5:848-52.