Pharmacotherapy for alcohol withdrawal

Hospital Pharmacy

Volumn 38, Issue 5, 2003, Pages

  Hodges, Brian M ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BENZODIAZEPINE DERIVATIVE; CLOMETHIAZOLE; CLONIDINE; DIAZEPAM; FLUNITRAZEPAM; HALOPERIDOL; LORAZEPAM; MIDAZOLAM; PHENOBARBITAL; PROPOFOL;

ALCOHOL WITHDRAWAL; CRITICAL ILLNESS; DELIRIUM TREMENS; HALLUCINATION; HUMAN; INTENSIVE CARE UNIT; PATHOPHYSIOLOGY; PROPHYLAXIS; REVIEW; SCREENING TEST;

EID: 0037615222     PISSN: 00185787     EISSN: None     Source Type: Journal    
DOI: 10.1177/001857870303800501     Document Type: Review

References (35)

1. Lieber CS. Medical disorders of alcoholism. N Engl J Med. 1995; 333(16):1058-65.
2. Saitz R, O'Malley SS. Pharmacotherapies for alcohol abuse. Withdrawal and treatment. Med Clin North Am. 1997;81(4):881-907.
3. Moore RD, Bone LR, Geller G, et al. Prevalence, detection, and treatment of alcoholism in hospitalized patients. JAMA. 1989;261(3):403-7.
4. Spies CD, Rommelspacher H. Alcohol withdrawal in the surgical patient: Prevention and treatment. Anesth Anal. 1999;88(4):946-54.
5. Jenkins DH. Substance abuse and withdrawal in the intensive care unit. Contemporary issues. Surg Clin North Am. 2000;80(3):1033-53.
6. Spies CD, Nordmann A, Brummer G, et al. Intensive care unit stay is prolonged in chronic alcoholic men following tumor resection of the upper digestive tract. Acta Anaesthesiol Scand. 1996; 40(6):649-56.
7. Chang PH, Steinberg MB. Alcohol withdrawal. Med Clin North Am. 2001;85(5):1191-212.
8. Freedland ES, McMicken DB. Alcohol-related seizures, Part 2: Clinical presentation and management. J Emerg Med. 1993;11(5):605-18.
9. Wojnar M, Bizon Z, Wasilewski D. The role of somatic disorders and physical injury in the development and course of alcohol withdrawal delirium. Alcohol Clin Exp Res. 1999;23(2):209-13.
10. Spies CD, Dubisz N, Neumann T, et al. Therapy of alcohol withdrawal syndrome in intensive care unit patients following trauma: results of a prospective, randomized trial. Crit Care Med. 1996;24(3):414-22.
11. Erstad BL, Cotugno CL. Management of alcohol withdrawal. Am J Health Syst Pharm. 1995;52(7):697-709.
12. Mayfield D, McLeod G, Hall P. The CAGE questionnaire: Validation of a new alcoholism screening instrument. Am J Psychiatry. 1974;131(10):1121-3.
13. Bush B, Shaw S, Cleary P, et al. Screening for alcohol abuse using the CAGE questionnaire. Am J Med. 1987;82(2):231-5.
14. Segatore M, Adams D, Lange S. Managing alcohol withdrawal in the acutely ill hospitalized adult. J Neurosci Nurs. 1999;31(3):129-41.
15. Schumacher L, Pruitt JN, Phillips M. Identifying patients "at risk" for alcohol withdrawal syndrome and a treatment protocol. J Neurosci Nurs. 2000; 32(3):158-63.
16. th ed. Washington, DC: American Psychiatric Association; 1994.
17. Sullivan JT, Sykora K, Schneiderman J, et al. Assessment of alcohol withdrawal: The revised clinical institute withdrawal assessment for alcohol scale (CIWA-Ar). Br J Addict. 1989; 84(11):1353-7.
18. Foy A, March S, Drinkwater V. Use of an objective clinical scale in the assessment and management of alcohol withdrawal in a large general hospital. Alcohol Clin Exp Res. 1988;12(3):360-4.
19. Anonymous. Management of the agitated intensive care unit patient. Crit Care Med. 2002;30(suppl 1):S97-S123.
20. Mayo-Smith MF. Pharmacological management of alcohol withdrawal. A meta-analysis and evidence-based practice guideline. American Society of Addiction Medicine Working Group on Pharmacological Management of Alcohol Withdrawal. JAMA. 1997;278(2): 144-51.
21. Holbrook AM, Crowther R, Lotter A, et al. Meta-analysis of benzodiazepine use in the treatment of acute alcohol withdrawal. CMAJ. 1999;160(5):649-55.
22. Solomon J, Rouck LA, Koepke HH. Double-blind comparison of lorazepam and chlordiazepoxide in the treatment of the acute alcohol abstinence syndrome. Clin Ther. 1983;6(1):52-8.
23. Kumar A, Bleck TP. Intravenous midazolam for the treatment of refractory status epilepticus. Crit Care Med. 1992;20(4):483-8.
24. Saitz R, Mayo-Smith MF, Roberts MS, et al. Individualized treatment for alcohol withdrawal. A randomized double-blind controlled trial. JAMA. 1994;272(7):519-23.
25. Daeppen JB, Gache P, Landry U, et al. Symptom-triggered vs fixed-schedule doses of benzodiazepine for alcohol withdrawal: A randomized treatment trial. Arch Intern Med. 2002;162(10): 1117-21.
26. Jaeger TM, Lohr RH, Pankratz VS. Symptom-triggered therapy for alcohol withdrawal syndrome in medical inpatients. Mayo Clin Proc. 2001;76(7):695-701.
27. Saitz R, Friedman LS, Mayo-Smith MF. Alcohol withdrawal: A nationwide survey of inpatient treatment practices. J Gen Intern Med. 1995;10(9):479-87.
28. Spies CD, Dubisz N, Funk W, et al. Prophylaxis of alcohol withdrawal syndrome in alcohol-dependent patients admitted to the intensive care unit after tumour resection. Br J Anaesth. 1995; 75:734-9.
29. Craft PP, Foil MB, Cunningham PR, et al. Intravenous ethanol for alcohol detoxification in trauma patients. South Med J. 1994;87(1):47-54.
30. Hansbrough JF, Zapata-Sirvent RL, Carroll WJ, et al. Administration of intravenous alcohol for prevention of withdrawal in alcoholic burn patients. Am J Surg. 1984;148(2):266-9.
31. Eggers V, Tio J, Neumann T, et al. Blood alcohol concentration for monitoring ethanol treatment to prevent alcohol withdrawal in the intensive care unit. Intensive Care Med. 2002;28:1475-82.
32. Wilkens L, Ruschulte H, Ruckoldt H, et al. Standard calculation of ethanol elimination rate is not sufficient to provide ethanol substitution therapy in the postoperative course of alcohol-dependent patients. Intensive Care Med. 1998;24(5):459-63.
33. McCowan C, Marik P. Refractory delirium tremens treated with propofol: A case series. Crit Care Med. 2000;28(6):1781-4.
34. Coomes TR, Smith SW. Successful use of propofol in refractory delirium tremens. Ann Emerg Med. 1997;30(6):825-8.
35. Currier DS, Bevacqua BK. Acute tachyphylaxis to propofol sedation during ethanol withdrawal. J Clin Anesth. 1997;9(5):420-3.