Safety and effectiveness of low-dose, oral vitamin K1 administration in asymptomatic out-patients on warfarin or acenocoumarol with excessive anticoagulation

Haematologica

Volumn 88, Issue 2, 2003, Pages 237-238

  Poli, Daniela ^a   Antonucci, Emilia ^b   Lombardi, Alessandra ^b   Gensini, Gian Franco ^b   Abbate, Rosanna ^b   Prisco, Domenico ^b  

^a Centro Trombosi   (Italy)

^b NONE

Author keywords

Oral anticoagulation; Overcoagulation; Vitamin K1

Indexed keywords

ACENOCOUMAROL; PHYTOMENADIONE; WARFARIN; ANTICOAGULANT AGENT; ANTIFIBRINOLYTIC AGENT;

ANTICOAGULATION; ARTICLE; BLEEDING; DOSE RESPONSE; DRUG EFFICACY; DRUG INDICATION; DRUG SAFETY; FOLLOW UP; HUMAN; INTERNATIONAL STANDARD UNIT; PATIENT MONITORING; AMBULATORY CARE; INTERNATIONAL NORMALIZED RATIO; INTOXICATION; LETTER; ORAL DRUG ADMINISTRATION; TREATMENT OUTCOME;

ACENOCOUMAROL; ADMINISTRATION, ORAL; AMBULATORY CARE; ANTICOAGULANTS; ANTIFIBRINOLYTIC AGENTS; FOLLOW-UP STUDIES; HUMANS; INTERNATIONAL NORMALIZED RATIO; OVERDOSE; TREATMENT OUTCOME; VITAMIN K 1; WARFARIN;

EID: 0037608685     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Crowther MA, Julian J, McCarty D, Douketis J, Kovacs M, Biagoni L, et al. Treatment of warfarin-associated coagulopathy with oral vitamin K: a randomised controlled trial. Lancet 2000;356:1551-3.
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4. Fondevila CG, Grosso SH, Santarelli MT, Pinto MD. Reversal of excessive oral anticoagulation with a low oral dose of vitamin K1 compared with acenocoumarine discontinuation. A prospective, randomized, open study. Blood Coagul Fibrinolysis 2001;12:9-16.
5. Rosendaal FR, Cannegieter SC, van der Meer FJ, Briet E. A method to determine the optimal intensity of oral anticoagulant therapy. Thromb Haemost 1993;69:236-9.