Acute nitrobenzene poisoning with severe associated methemoglobinemia: Identification in whole blood by GC-FID and GC-MS

Journal of Analytical Toxicology

Volumn 27, Issue 4, 2003, Pages 221-225

  Martinez M A ^a   Ballesteros, S ^b   Almarza, E ^a   Sanchez de la Torre C ^a   Bua S ^c  

^a Ministerio de Justicia   (Spain)

^b Institute of Toxicology   (Spain)

^c HOSPITAL DE MÓSTOLES   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

NITROBENZENE;

AGED; ARTICLE; BLOOD SAMPLING; BRAIN ISCHEMIA; CASE REPORT; CLINICAL FEATURE; COMA; CYANOSIS; EXCHANGE BLOOD TRANSFUSION; GAS CHROMATOGRAPHY; GLASGOW COMA SCALE; HUMAN; HYPOTENSION; INTENSIVE CARE UNIT; INTOXICATION; KIDNEY FAILURE; MALE; MASS SPECTROMETRY; METHEMOGLOBINEMIA; QUANTITATIVE ANALYSIS; SELF POISONING; SYMPTOM;

EID: 0037605907     PISSN: 01464760     EISSN: None     Source Type: Journal    
DOI: 10.1093/jat/27.4.221     Document Type: Article

References (23)

1. A.F. Rosemarie. Toxicity summary for nitrobenzene (Online). http:/www.risk.lsd.ornl.gov/tox/profiles/nitrobenzene_f_V1.shtml (March, 1993), Oak Ridge National Laboratory, Oak Ridge, TN.
2. J.K. Piotrowski. Further investigations on the evaluation of exposure to nitrobenzene. Br. J. Ind. Med. 24: 60-67 (1967).
3. A. Finan, P. Keenan, F. O'Donovan, P. Mayne, and J. Murphy. Methaemoglobinemia associated with sodium nitrite in three siblings. B.M.J. 317: 1138-1139 (1998).
4. A. Mansouri. Review: Methemoglobinemia. Am. J. Med. Sci. 289: 200-209 (1985).
5. J.D.N. Nabarro. A case of acute mononitrobenzene poisoning. B.M.J 1: 929-931 (1948).
6. Z. Mysiak, J.K. Piotrowski, and E. Musialowicz. Acute nitrobenzene poisoning. Arch. Toxicol. 28: 208-213 (1971).
7. L. Lareng, R. Bierne, M.J. Jorda, B. Cathala, and M. Fabre. Acute toxic methemoglobinemia from accidental ingestion of nitrobenzene. Eur. J. Toxicol. Environ. Hyg. 7: 12-16 (1974).
8. M.R. Harrison. Toxic methemoglobinemia: a case of acute nitrobenzene and aniline poisoning treated by exchange transfusion. Anaesthesia 32: 270-272 (1977).
9. M.A. Schimelman, J.M. Soler, and H.A. Muller. Methemoglobinemia: Nitrobenzene ingestion. J.A.C.E.P. 7: 406-408 (1978).
10. R.C. Baselt. Biological monitoring methods for industrial chemicals, 2nd ed. PSG Publishing Company, Inc., Littleton, MA, 1988, pp 233-236.
11. R. Ewert, F. Buttgereit, M. Prügel, and P. Reinke. Intravenous injection of India ink with suicidal intent. Int. J. Med. Legal Med. 111: 91-92 (1998).
12. D.S. Chongtham, J. Phurailatpam, M.M. Singh, and T.R. Singh. Methaemoglobinemia in nitrobenzene poisoning. J. Postgrad. Med. 43: 73-74 (1997).
13. D.S. Chongtham, J. Phurailatpam, M.M. Singh, and T.R. Singh. Methaemoglobinemia in nitrobenzene poisoning - A case report. J. Indian. Med. Assoc. 97: 469-470 (1999).
14. G. Gupta, B. Poddar, M. Salaria, and V. Parmar. Acute nitrobenzene poisoning. Indian Pediatr. 37: 1147-1148 (2000).
15. K.C. Osterhoudt, C.C. Wiley, R. Dudley, S. Sheen, and F.M. Henretig. Rebound severe methemoglobinemia from ingestion of a nitroethane artificial-fingernail remover. J. Pediatric. 126: 819-821 (1995).
16. P.B. Casey, B.M. Buckley, and J.A. Vale. Methemoglobinemia following ingestion of a monolinuron/paraquat herbicide (Gramonol®). J. Tox. Clin. Toxicol. 32: 185-189 (1994).
17. C.C. Yang, S.F. Hwang, M.M. Chou, and J.F. Deng. Metobromuron/metolachlor ingestion with late-onset methemoglobinemia in a pregnant woman successfully treated with methylene blue. J. Tox. Clin. Toxicol. 33: 713-716 (1995).
18. M.H. Cummings, S. Day, S. Norton, G. Cook, and W.D. Alexander. Petrol octane booster and methaemoglobinaemia. J. Intern. Med. 235: 279-280 (1994).
19. J.K. Piotrowski. Exposure Test for Organic Compounds in Industrial Toxicology. Government Printing Office, Washington, D.C., 1977, pp 76-80.
20. J. Salmowa, J.K. Piotrowski, and U. Neuhorn. Evaluation to exposure to nitrobenzene. Br. J. Ind. Med. 20: 41-46 (1963).
21. J.W. Harvey and A.S. Keitt. Studies of the efficacy and potential hazards of methylene blue therapy in aniline-induced methaemoglobinemia. Br. J. Hematol. 54: 29-41 (1983).
22. S.C. Curry and M.W. Cartton. Hematologic consequences of poisoning. In Clinical Management of Poisoning and Drug Overdose, 3rd ed., L.M. Haddad, M.W Shannon and J.F. Winchester, Eds. W.B. Saunders, Philadelphia, PA, 1998, pp 225-230.
23. V.K. Shormanov and L.V. Bredikhina. Isolation of nitrobenzene from biological material. Sud. Med. Ekspert. 43: 28-30 (2000).