Oral treatment of avian lead intoxication with meso-2,3-dimercaptosuccinic acid

Journal of Zoo and Wildlife Medicine

Volumn 34, Issue 1, 2003, Pages 82-87

  Hoogesteijn, Almira L ^a,b   Raphael, Bonnie L ^b   Calle, Paul ^b   Cook, Robert ^b   Kollias, George ^a  

^a Department of Obstetrics Gynecology   (United States)

^b WILDLIFE CONSERVATION SOCIETY   (United States)

Author keywords

Birds; DMSA; Lead toxicity; Meso dimercaptosuccinic acid; Succimer

Indexed keywords

AVES; GALLIFORMES;

CHELATING AGENT; LEAD; SUCCIMER;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIRD; BIRD DISEASE; BLOOD; CHEMICALLY INDUCED DISORDER; LEAD POISONING; LONGITUDINAL STUDY; ORAL DRUG ADMINISTRATION; REGRESSION ANALYSIS; RETROSPECTIVE STUDY; ZOO ANIMAL;

ADMINISTRATION, ORAL; ANIMALS; ANIMALS, ZOO; BIRD DISEASES; BIRDS; CHELATING AGENTS; LEAD; LEAD POISONING; LONGITUDINAL STUDIES; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; SUCCIMER;

EID: 0037591358     PISSN: 10427260     EISSN: None     Source Type: Journal    
DOI: 10.1638/1042-7260(2003)34[0082:OTOALI]2.0.CO;2     Document Type: Article

References (21)

1. Aposhian, H. V., R. M. Maiorino, R. D. Gonzalez, C. M. Zuniga, Z. Xu, K. M. Hurlbut, M. P. Junco, R. C. Dart, and M. M. Aposhian. 1995. Mobilization of heavy metals by newer, therapeutically useful chelating agents. Toxicology 97: 23-38.
2. Bagley, G. E., and L. N. Locke. 1967. The occurrence of lead in tissues of wild birds. Bull. Environ. Contam. Toxicol. 2: 297-305.
3. Besunder, J. B., D. M. Super, and R. I. Anderson. 1997. Comparison of dimercaptosuccinic acid and calcium disodium ethylenediaminetetraacetic acid versus dimercaptopropanol and ethylenediaminetetraacetic acid in children with lead poisoning. J. Pediatr. 130: 966-971.
4. Chisolm, J. J. 1992. BAL, EDTA, DMSA and DMPS in the treatment of lead poisoning in children. J. Toxicol. 30: 493-504.
5. Cory-Slechta, D., B. Weiss, and C. Cox. 1987. Mobilization and redistribution of lead over the course of calcium disodium ethylenediamine tetraacetate chelation therapy. Toxicol. Appl. Pharmacol. 243: 804-813.
6. Degernes, L., R. Frank, M. Freeman, and P. Redig. 1989. Lead poisoning in trumpeter swans. Proc. Assoc. Avian Vet. 1989: 144-155.
7. Denver, M. C., L. A. Tell, F. D. Galey, J. G. Trupkiewicz, and U. Kass. 2000. Comparison of two heavy metal chelators for treatment of lead toxicosis in cockatiels. Am. J. Vet. Res. 61: 935-940.
8. Flora, S. J., R. Bhattacharya, and R. P. Vijayaraghavan. 1995. Combined therapeutic potential of meso-2,3-dimercaptosuccinic acid and calcium disodium edetate on the mobilization and distribution of lead in experimental lead intoxication in rats. Fundam. Appl. Toxicol. 25: 233-240.
9. Friend, M., and J. C. Franson. 1999. Lead. In: Friend, M., and J. C. Franson (eds.). Field Manual of Wildlife Disease. U.S. Department of the Interior. U.S. Geological Survey, Washington, D.C. Pp. 317-336.
10. Goyer, R. A. 1996. Toxic effect of metals. In: Klaassen, C. D. (ed.). Casarett and Doull's Toxicology. McGraw-Hill, New York, New York. Pp. 691-736.
11. Goyer, R. A., M. G. Cherian, and M. M. Jones. 1995. Role of chelating agents for prevention, intervention, and treatment of exposures to toxic metals. Environ. Health Perspect. 103: 1048-1052.
12. Grandjean, P., I. Jacobsen, and P. Jorgensen. 1991. Chronic lead poisoning treated with dimercaptosuccinic acid. Pharmacol. Toxicol. 68: 266-269.
13. Hammond, P. B. 1973. The effects of chelating agents on the tissue distribution and excretion of lead. Toxicol. Appl. Pharmacol. 18: 296-310.
14. Kostial, K., M. Blanusa, M. Piasek, N. Restek-Samarzija, and M. M. Jones. 1999. Combined chelation therapy in reducing tissue lead concentrations in suckling rats. J. Appl. Toxicol. 19: 143-147.
15. Liang, Y. Y., J. C. Zhang, Z. Q. Tao, X. M. Yan, X. H. Xu, and Z. J. Chen. 1994. Effects of DMSA per-os on excretion of lead and mercury in mice. Acta Pharmacol. Sin. 15: 379-382.
16. Mann, K. V., and J. D. Travers. 1991. Succimer, an oral lead chelator. Clin. Pharm. 10: 914-922.
17. Mautino, M. 1990. Avian lead intoxication. Proc. Assoc. Avian Vet. 1990: 245-247.
18. Mautino, M. 1997. Lead and zinc intoxication in zoological medicine: a review. J. Zoo Wildl. Med. 28: 28-35.
19. Ramsey, D. T., S. W. Casteel, A. M. Faggella, C. B. Chastain, J. W. Nunn, and V. M. Schaeffer. 1996. Use of orally administered succimer (meso-2,3-dimercaptosuccinic acid) for treatment of lead poisoning in dogs. J. Am. Vet. Med. Assoc. 208: 371-375.
20. 2EDTA-treated lead-toxic children. Environ. Health Perspect. 93: 271-277.
21. Tandon, S. K., S. Singh, and L. I. Jain. 1994. Efficacy of combined chelation in lead intoxication. Chem. Res. Toxicol. 7: 585-589.