Acute ischemia/reperfusion injury after isogeneic kidney transplantation is mitigated in a rat model of chronic renal failure

American Journal of Transplantation

Volumn 3, Issue 5, 2003, Pages 570-580

  Vercauterena, Sven R ^a   Ysebaert, Dirk K ^a   Van Rompay, An R ^a   De Greef, Kathleen E ^a   De Broe, Marc E ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Chronic renal failure; Ischemia; Leukocytes; Multifactorial rat model; Reperfusion injury; Transplantation

Indexed keywords

ACUTE KIDNEY TUBULE NECROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL REGENERATION; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE PREDISPOSITION; EPITHELIUM CELL; GLOMERULUS FILTRATION; ISOGRAFT; KIDNEY FUNCTION; KIDNEY FUNCTION TEST; KIDNEY ISCHEMIA; KIDNEY TRANSPLANTATION; MACROPHAGE; NEPHRECTOMY; NONHUMAN; POSTOPERATIVE PERIOD; RAT; RAT STRAIN; REPERFUSION INJURY; T LYMPHOCYTE; TREATMENT OUTCOME; UREMIA;

ANIMALS; BODY WEIGHT; GRAFT SURVIVAL; IMMUNOHISTOCHEMISTRY; ISCHEMIA; KIDNEY; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; LEUKOCYTES; MACROPHAGES; NEUTROPHILS; RATS; RATS, INBRED LEW; RENAL CIRCULATION; REPERFUSION INJURY; T-LYMPHOCYTES; TIME FACTORS; TRANSPLANTATION, ISOGENEIC;

EID: 0037570837     PISSN: 16006135     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-6143.2003.00117.x     Document Type: Article

References (41)

1. Lameire N, Verbeke M, Vanholder R. Prevention of clinical acute tubular necrosis with drug therapy. Nephrol Dial Transplant 1995; 10: 1992-2000.
2. DuBose TD, Jr., Warnock DG, Mehta RL et al. Acute renal failure in the 21st century: recommendations for management and outcomes assessment. Am J Kidney Dis 1997; 29: 793-799.
3. Druml W, Lax F, Grimm G, Schneeweiss B, Lenz K, Laggner AN. Acute renal failure in the elderly 1975-1990. Clin Nephrol 1994; 41: 342-349.
4. Chew SL, Lins RL, Daelemans R, De Broe ME. Outcome in acute renal failure. Nephrol Dial Transplant 1993; 8: 101-107.
5. Novis BK, Roizen MF, Aronson S, Thisted RA. Association of preoperative risk factors with postoperative acute renal failure. Anesth Analg 1994; 78: 143-149.
6. Abrass CK. Renal biopsy in the elderly [editorial]. Am J Kidney Dis 2000; 35: 544-546.
7. Lu CY, Penfield JG, Kielar ML, Vazquez MA, Jeyarajah DR. Hypothesis: is renal allograft rejection initiated by the response to injury sustained during the transplant process? Kidney Int 1999; 55: 2157-2168.
8. Vercauteren SR, Ysebaert DK, De Greef KE, Eyskens EJ, De Broe ME. Chronic reduction in renal mass in the rat attenuates ischemia/reperfusion injury and does not impair tubular regeneration. J Am Soc Nephrol 1999; 10: 2551-2561.
9. Fisher BLS. Microvascular surgical techniques in research with special reference to renal transplantation in the rat. Surgery 1965; 58: 904-914.
10. Provoost AP, de Keijzer MH, Kort WJ, Wolff ED, Molenaar JC. The glomerular filtration rate of isogeneically transplanted rat kidneys. Kidney Int 1982; 21: 459-469.
11. Bradford M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Annal Biochem 1976; 72: 248-254.
12. Ysebaert DK, De Greef KE, Vercauteren SR et al. Identification and kinetics of leukocytes after severe ischaemia/reperfusion renal injury. Nephrol Dial Transplant 2000; 15: 1562-1574.
13. Brezis M, Rosen S, Epstein FH. Acute Renal Failure Due To Ischemia (Acute Tubular Necrosis). In: Lazarus JM, Brenner BM (eds): Acute renal failure. New York: Churchill Livingstone, 1993: 207-229.
14. Molitoris BA, Weinberg JM, Venkatachalam MA, Zager RA, Nath KA, Goligorsky MS. Acute renal failure. II. Experimental models of acute renal failure: imperfect but indispensable. Am J Physiol Renal Physiol 2000; 278: F1-F12.
15. Sheridan AM, Bonventre JV. Cell biology and molecular mechanisms of injury in ischemic acute renal failure. Curr Opin Nephrol Hypertens 2000; 9: 427-434.
16. Finn WF, Fernandez-Repollet E, Goldfarb D, Iaina A, Eliahou HE. Attenuation of injury due to unilateral renal ischemia: delayed effects of contralateral nephrectomy. J Lab Clin Med 1984; 103: 193-203.
17. Fried TA, Hishida A, Barnes JL, Stein JH. Ischemic acute renal failure in the rat: protective effect of uninephrectomy. Am J Physiol 1984; 247: F568-F574.
18. Coffman TM, Sanfilippo FP, Brazy PC, Yarger WE, Klotman PE. Bilateral native nephrectomy improves renal isograft function in rats. Kidney Int 1986; 30: 20-26.
19. Lieberthal W. Biology of ischemic and toxic renal tubular cell injury: role of nitric oxide and the inflammatory response. Curr Opin Nephrol Hypertens 1998; 7: 289-295.
20. De Greef KE, Ysebaert DK, Dauwe S et al. Anti-B7-1 blocks mononuclear cell adherence in vasa recta after ischemia. Kidney Int 2001; 60: 1415-1427.
21. Descamps-Latscha B, Herbelin A, Nguyen AT et al. Balance between IL-1 beta, TNF-alpha, and their specific inhibitors in chronic renal failure and maintenance dialysis. Relationships with activation markers of T cells, B cells, and monocytes. J Immunol 1995; 154: 882-892.
22. Hörl WH. The patient with uremia. In: Davison AM, Cameron JS, Grünfeld JP, Kerr DNS, Ritz E, Winearls CG (eds): Oxford textbook of clinincal nephrology. Oxford: Oxford University Press, 1998: 1822-1936.
23. Heinzelmann M, Mercer-Jones MA, Passmore JC. Neutrophils and renal failure. Am J Kidney Dis 1999, 34:384-399.
24. Kaul H, Girndt M, Sester U, Sester M, Kohler H. Initiation of hemodialysis treatment leads to improvement of T-cell activation in patients with end-stage renal disease. Am J Kidney Dis 2000; 35: 611-616.
25. Girndt M, Sester M, Sester U, Kaul H, Köhler H. Molecular aspects of T- and B-cell function in uremia. Kidney Int 2001; 59 (suppl. 78): S206-S211.
26. Dou L, Cerini C, Brunet P et al. P-cresol, a uremic toxin, decreases endothelial cell response to inflammatory cytokines. Kidney Int 2002; 62: 1999-2009.
27. Weinberg JM. The cell biology of ischemic renal injury. Kidney Int 1991; 39: 476-500.
28. Bonventre JV. Mechanisms of ischemic acute renal failure. Kidney Int 1993; 43: 1160-1178.
29. Zager RA. Alterations of intravascular volume: influence on renal susceptibility to ischemic injury. J Lab Clin Med 1986; 108: 60-69.
30. Bell RH, Jr., Borjesson BA, Wolf PL et al. Quantitative morphological studies of aging changes in the kidney of the Lewis rat. Ren Physiol 1984; 7: 176-184.
31. Griffin KA, Picken M, Bidani AK. Method of renal mass reduction is a critical modulator of subsequent hypertension and glomerular injury. J Am Soc Nephrol 1994; 4: 2023-2031.
32. Zager RA, Mahan J, Merola AJ. Effects of mannitol on the postischemic kidney. Biochemical, functional, and morphologic assessments. Lab Invest 1985; 53: 433-442.
33. Zager RA. Obstruction of proximal tubules initiates cytoresistance against hypoxic damage. Kidney Int 1995; 47: 628-637.
34. Conger JD. Drug Therapy in acute renal failure. In: Lazarus JM, Brenner BM (eds): Acute renal failure. New York: Churchill Livingstone, 1993: 527-552.
35. Brezis M, Rosen S. Hypoxia of the renal medulla - its implications for disease. N Engl J Med 1995; 332: 647-655.
36. Kelly KJ, Molitoris BA. Acute renal failure in the new millennium: time to consider combination therapy. Semin Nephrol 2000; 20: 4-19.
37. Vogt BA, Alam J, Croatt AJ, Vercellotti GM, Nath KA. Acquired resistance to acute oxidative stress. Possible role of heme oxygenase and ferritin. Lab Invest 1995; 72: 474-483.
38. Park KM, Chen A, Bonventre JV. Prevention of kidney ischemia/reperfusion-induced functional injury, JNK, p38, and MAP kinase kinase activation by remote ischemic pretreatment. J Biol Chem 2001; 276.
39. Zager RA, Burkhart KM, Johnson AC, Sacks BM. Increased proximal tubular cholesterol content: implications for cell injury and "acquired cytoresistance". Kidney Int 1999; 56: 1788-1797.
40. Lee HT, Emala CW. Protective effects of renal ischemic preconditioning and adenosine pretreatment: role of A(1) and A(3) receptors. Am J Physiol Renal Physiol 2000; 278: F380-F387.
41. Mange KC, Joffe MM, Feldman HI. Effect of the use of nonuse of long-term dialysis on the subsequent survival of renal transplants from living donors. N Engl J Med 2001; 344: 726-731.