Collagen fibrils appear more closely packed in the prepupillary cornea: Optical and biomechanical implications

Investigative Ophthalmology and Visual Science

Volumn 44, Issue 7, 2003, Pages 2941-2948

  Boote, Craig ^a   Dennis, Sally ^b   Newton, Richard H ^b   Puri, Hina ^b   Meek, Keith M ^b  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN FIBRIL;

ANISOTROPY; ARTICLE; BIOMECHANICS; CORNEA; CORNEA CURVATURE; CORNEA LIMBUS; CORNEA OPACITY; EYE SURGERY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MEASUREMENT; NORMAL HUMAN; PRIORITY JOURNAL; REFRACTION INDEX; STRENGTH; THICKNESS; X RAY DIFFRACTION;

BIOMECHANICS; COLLAGEN; CORNEAL STROMA; HUMANS; X-RAY DIFFRACTION;

EID: 0037562793     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.03-0131     Document Type: Article

References (31)

1. Waring GO. Making sense of keratospeak II: proposed conventional terminology for corneal topography. Refract Corn Surg. 1989;5:362-367.
2. Maurice DM. The structure and transparency of the corneal stroma. J Physiol 1957;136:263-286.
3. Hukins DWL, Aspden RM. Composition and properties of connective tissues. Trends Biochem Sci. 1985;10:260-264.
4. Jeronimidis G, Vincent JFV. Composite materials. In: Hukins DWL ed. Connective Tissue Matrix. Macmillan; 1984:187-210.
5. Farrell RA. Corneal transparency. In: Albert DM, Jacobiec SA, eds. Principles and Practice of Ophthalmology. Philadelphia: Saunders; 1994.
6. Meek KM, Quantock AJ. The use of X-ray scattering techniques to determine corneal ultrastructure. Prog Retinal Eye Res. 2001;20:95-137.
7. Meek KM, Leonard DW. Ultrastructure of the corneal stroma: a comparative study. Biophys J. 1993;64:273-280.
8. Freund DE, McCally RL, Farrell RA, Cristol SM, L'Hernault NL, Edelhauser HF. Ultrastructure in anterior and posterior stroma of perfused human and rabbit corneas: relation to transparency. Invest Ophthalmol Vis Sci. 1995;36:1508-1523.
9. Kanai A, Kaufman HE. Electron microscopic studies of corneal stroma: ageing changes of collagen fibres. Ann Ophthalmol. 1973;5:285-292.
10. Craig AS, Parry DAD. Collagen fibrils of the vertebrate corneal stroma. J Ultra Mol Struct Res. 1981;74:232-239.
11. Borcherding MS, Blacik LJ, Sittig RA, Bizzell JW, Breen M, Weinstein HG. Proteoglycans and collagen fibre organisation in human corneoscleral tissue. Exp Eye Res. 1975;21:59-70.
12. Fullwood NJ, Meek KM. A synchrotron X-ray study of the changes occurring in the corneal stroma during processing for electron-microscopy. J Microsc. 1993;169:53-60.
13. Craig AS, Robertson JG, Parry DAD. Preservation of corneal collagen fibril structure using low-temperature procedures for electron microscopy. J Ultra Mol Struct Res. 1986;96:172-175.
14. Daxer A, Misof K, Grabner B, Ettl A, Fratzl P. Collagen fibrils in the human corneal stroma: structure and ageing. Invest Ophthalmol Vis Sci. 1998;39:644-648.
15. Oster G, Riley DP. Scattering from cylindrically symmetric systems. Acta Crystallogr. 1952;5:272-276.
16. Worthington CR, Inouye H. X-ray diffraction study of the cornea. Int J Biol Macromol. 1985;7:2-8.
17. Meek KM, Fullwood NJ, Cooke PH, et al. Synchrotron X-ray diffraction studies of the cornea, with implications for stromal hydration. Biophys J. 1991;60:467-474.
18. Hart RW, Farrell RA. Light scattering in the cornea. J Opt Soc Am. 1969;59:766-774.
19. Freund DE, McCally RL, Farrell RA. Direct summation of fields for light scattering by fibrils with applications to normal corneas. Appl Opt. 1986;25:2739-2746.
20. Martola EL, Baum JL. Central and peripheral corneal thickness. Arch Ophthalmol. 1968;79:28-30.
21. Edmund C. Determination of the corneal thickness profile by optical pachometry. Acta Ophthalmol. 1987;65:147-152.
22. Leonard DW, Meek KM. Estimation of the refractive indices of collagen fibrils and ground substance of the corneal stroma using data from X-ray diffraction. Biophys J. 1997;72:1382-1387.
23. Krenchel H. Fibre Reinforcement. Copenhagen, Denmark: Akademisk Forlag; 1964.
24. Maurice DM. The cornea and sclera. In: Davson H, ed. The Eye. New York: Academic Press; 1969:489-599.
25. Muir H, Bullough P, Maroudas A. The distribution of collagen in human articular cartilage with some of its physiological implications. J Bone Surg Ser B. 1970;50:554-563.
26. Fratzl P, Daxer A. Structural transformation of collagen fibrils in corneal stroma during drying: an X-ray scattering study. Biophys J. 1993;64:1210-1214.
27. Hanna KD, Jouve FE, Waring GO, Ciarlet PG. Computer simulation of arcuate keratotomy for astigmatism. Refract Corneal Surg. 1992;8:152-163.
28. Moreira H, Campos M, Sawush MR, McDonnell JM, Sand B, McDonald PJ. Holmium laser thermokeratoplasty. Ophthalmology. 1993;100:752-761.
29. Newton RH, Meek KM. The integration of the corneal and limbal fibrils in the human eye. Biophys J. 1998;75:2508-2512.
30. Newton RH, Meek KM. Circumcorneal annulus of collagen fibrils in the human limbus. Invest Ophthalmol Vis Sci. 1998;39:1125-1134.
31. Meek KM, Newton RH. Organisation of collagen fibrils in the corneal stroma in relation to mechanical properties and surgical practice. J Refract Surg. 1999;15:695-699.