Treatment of early RA in clinical practice: A comparative study of two different DMARD/corticosteroid options

Clinical and Experimental Rheumatology

Volumn 21, Issue 3, 2003, Pages 327-332

  Svensson, Björn ^a   Ahlmén, Monica ^b   Forslind, Kristina ^a   Bratt, Johan ^c   Hafström, Ingiäld ^c   Keller, Catharina ^c   Leden, Ido ^c   Lindell, Bengt ^c   Petersson, Ingemar ^c   Schaufelberger, Christopher ^c   Teleman, Annika ^c   Theander, Jan ^c  

^a Rheumatology Section   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c NONE

Author keywords

Corticosteroids; DAS28; DMARD treatment; Early RA; EULAR response criteria; HAQ; Larsen score; Outcome; Remission

Indexed keywords

ANTIRHEUMATIC AGENT; CORTICOSTEROID; METHOTREXATE; PREDNISOLONE; SALAZOSULFAPYRIDINE;

ADULT; AGED; ARTICLE; CLINICAL PRACTICE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; DOSE RESPONSE; DRUG RESPONSE; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; INDIVIDUALIZATION; JOINT RADIOGRAPHY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REMISSION; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SIDE EFFECT; STATISTICAL ANALYSIS; TREATMENT FAILURE; TREATMENT OUTCOME;

ADULT; AGED; ARTHRITIS, RHEUMATOID; CHI-SQUARE DISTRIBUTION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; METHOTREXATE; MIDDLE AGED; PAIN MEASUREMENT; PATIENT SATISFACTION; PREDNISOLONE; RANGE OF MOTION, ARTICULAR; REFERENCE VALUES; RHEUMATOLOGY; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; STATISTICS, NONPARAMETRIC; SULFASALAZINE; TREATMENT OUTCOME;

EID: 0037534429     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. MÖTTÖNEN T, PAIMELA L, LEIRISALO-REPO M, KAUTIAINEN H, ILONEN J, HANNONEN P: Only high disease activity and positive rheumatoid factor indicate poor prognosis in patients with early RA treated with "sawtooth" strategy. Ann Rheum Dis 1998; 57: 533-9.
2. ACR SUBCOMMITTEE ON RA GUIDELINES: Guidelines for the management of rheumatoid arthritis. Arthritis Rheum 2002; 46: 328-46.
3. O'DELL J: How is it best to treat early RA patients ? Best Prac Res Clin Rheumatol 2001; 15: 125-37.
4. MAETZEL A, WONG A, STRAND V, TUGWELL P, WELLS G, BOMBARDIER C: Meta-analysis of treatment termination rates among RA patients receiving DMARDs. Rheumatology 2001; 39: 975-81.
5. VAN DE PUTTE LBA, KROOT EJA, VAN RIEL PLCM: Management of refractory RA. Rheumatology 1999; 38 (Suppl.): 32-4.
6. QUINN MA, GREEN MJ, CONAGHAN P, EMERY P: How do you diagnose RA early? Best Pract Res Clin Rheumatol 2001; 15: 49-66.
7. ARNETT FC, EDWORTHY SM, BLOCK A et al.: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315-24.
8. VAN DER HEIJDE DMFM, VAN'T HOF MA, VAN RIEL PLCM, VAN LEEUWEN MA, VAN RIJSWIK MH, VAN DE PUTTE LBA: Validity of single variables and composite indices for measuring disease activity in rheumatoid arthritis. Ann Rheum Dis 1992; 51: 177-81.
9. VAN GESTEL AM, HAAGSMA CJ, VAN RIEL PLCM: Validation of rheumatoid arthritis improvement criteria that include simplified joint counts. Arthritis Rheum 1998; 41: 1845-50.
10. EKDAHL C, EBERHARDT K, ANDERSSON I, SVENSSON B: Assessing disability in patients with rheumatoid arthritis. Scand J Rheumatol 1988; 17: 263-71.
11. FRIES JF, SPIT P, KRAINES RG, HOLMAN HR: Measurement of patient outcome in arthritis. Arthritis Rheum 1980; 23: 137-45.
12. DALE K LARSEN A: Radiographic damage assessment: The method and technique. Rheumatology in Europe 1994; 23: 136-41.
13. PREVOO MLL, VAN GESTEL AM, VAN'T HOF MA, VAN RIJSWIJK MH, VAN DE PUTTE LBA, VAN RIEL PLCM: Remission in a prospective study of patients with rheumatoid arthritis. American Rheumatism Association preliminary remission criteria in relation to the disease activity score. Br J Rheumatol 1996; 35: 1101-5.
14. DOUGADOS M, COMBE B, CANTAGREL A et al.: Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components. Ann Rheum Dis 1999; 58:220-5.
15. SMOLEN JS, KALDEN JR, SCOTT DL et al.: Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active RA: A double blind, randomised, multicenter study. Lancet 1999; 353: 259-66.
16. LIPSKY P, VAN DER HEIJDE DFM, ST CLAIR EW et al.: Infliximab and methotrexate in the treatment of RA. N Engl Med J 2000; 343: 1594-1602.
17. LERNDAL T, SVENSSON B: A clinical study of CPH82 vs. methotrexate in early rheumatoid arthritis. Rheumatology 2000; 39; 3: 316-20.
18. KIRWANN JR and the ARTHRITIS AND RHEUMATISM COUNCIL LOW DOSE GLUCOCORTICOID STUDY GROUP: The effect of glucocorticoids on joint destruction in RA. N Engl J Med 1995; 333: 142-6.
19. VAN EVERDINGEN AA, JACOBS JWG, SIEWERTSZ DR, BIJSMA JWJ: Low-dose prednisone therapy for patients with early active RA: Clinical efficacy, disease modifying properties and side effects. Ann Intern Med 2002; 136: 1-12.