Preserved response of mitochondrial function to short-term endurance training in skeletal muscle of heart transplant recipients

Journal of the American College of Cardiology

Volumn 42, Issue 1, 2003, Pages 126-132

  Zoll, Joffrey ^a   N'Guessan, Benoit ^a   Ribera, Florence ^a   Lampert, Eliane ^a   Fortin, Dominique ^b   Veksler, Vladimir ^b   Bigard, Xavier ^c   Geny, Bernard ^a   Lonsdorfer, Jean ^a   Ventura Clapier, Renée ^b   Mettauer, Bertrand ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b INSERM   (France)

^c CENTRE DE RECHERCHES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; CITRATE SYNTHASE; CREATINE; CREATINE KINASE; CREATINE PHOSPHATE; CYCLOSPORIN A; CYTOCHROME C OXIDASE; IMMUNOSUPPRESSIVE AGENT; PREDNISONE; SAPONIN;

ADULT; AEROBIC CAPACITY; ARTICLE; BIOSYNTHESIS; CELL MEMBRANE PERMEABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; ENDURANCE; ENZYME ACTIVITY; ENZYME ASSAY; EXERCISE TEST; FEMALE; GRAFT REJECTION; HEART TRANSPLANTATION; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; MALE; MITOCHONDRIAL RESPIRATION; MUSCLE BIOPSY; MUSCLE CELL; MUSCLE MITOCHONDRION; OXIDATIVE PHOSPHORYLATION; PHYSICAL ACTIVITY; PRIORITY JOURNAL; REGULATORY MECHANISM; SITTING; SKELETAL MUSCLE; TRAINING; VASTUS LATERALIS MUSCLE;

EID: 0037530414     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(03)00499-6     Document Type: Article

References (37)

1. Levine TB, Olivari MT, Cohn JN. Effects of orthotopic heart transplantation on sympathetic control mechanisms in congestive heart failure. Am J Cardiol 1986;58:1035-40.
2. Mettauer B, Lampert E, Petitjean P, et al. Persistent exercise intolerance following cardiac transplantation despite normal oxygen transport. Int J Sports Med 1996;17:277-86.
3. Stratton JR, Kemp GJ, Daly RC, Yacoub M, Rajagopalan B. Effects of cardiac transplantation on bioenergetic abnormalities of skeletal muscle in congestive heart failure. Circulation 1994;89:1624-31.
4. Bruce RA, Kusumi F, Niederberger M, Petersen JL. Cardiovascular mechanisms of functional aerobic impairment in patients with coronary artery disease. Circulation 1974;49:696-702.
5. Schaufelberger M, Eriksson BO, Lonn L, et al. Skeletal muscle characteristics, muscle strength and thigh muscle area in patients before and after cardiac transplantation. Eur J Heart Fail 2001;3:59-67.
6. Lampert E, Mettauer B, Hoppeler H, et al. Structure of skeletal muscle in heart transplant recipients. J Am Coll Cardiol 1996;28:980-4.
7. Lampert E, Mettauer B, Hoppeler H, et al. Skeletal muscle response to short endurance training in heart transplant recipients. J Am Coll Cardiol 1998;32:420-6.
8. Hokanson JF, Mercier JG, Brooks GA. Cyclosporine A decreases rat skeletal muscle mitochondrial respiration in vitro. Am J Respir Crit Care Med 1995;151:1848-51.
9. Mercier JG, Hokanson JF, Brooks GA. Effects of cyclosporine A on skeletal muscle mitochondrial respiration and endurance time in rats. Am J Respir Crit Care Med 1995;151:1532-6.
10. Sanchez H, Bigard X, Veksler V, et al. Immunosuppressive treatment affects cardiac and skeletal muscle mitochondria by the toxic effect of vehicle. J Mol Cell Cardiol 2000;32:323-31.
11. Sanchez H, Zoll J, Bigard X, et al. Effect of cyclosporin A and its vehicle on cardiac and skeletal muscle mitochondria: relationship to efficacy of the respiratory chain. Br J Pharmacol 2001;133:781-8.
12. Kavanagh T, Yacoub MH, Mertens DJ, et al. Cardiorespiratory responses to exercise training after orthotopic cardiac transplantation. Circulation 1988;77:162-71.
13. Keteyian S, Shepard R, Ehrman J, et al. Cardiovascular responses of heart transplant patients to exercise training. J Appl Physiol 1991;70:2627-31.
14. Squires RW. Exercise training after cardiac transplantation. Med Sci Sports Exerc 1991;23:686-94.
15. Badenhop DT. The therapeutic role of exercise in patients with orthotopic heart transplant. Med Sci Sports Exerc 1995;27:975-85.
16. Mettauer B, Zoll J, Sanchez H, et al. Oxidative capacity of skeletal muscle in heart failure patients versus sedentary or active control subjects. J Am Coll Cardiol 2001;38:947-54.
17. Zoll J, Sanchez H, N'Guessan B, et al. Physical activity changes the regulation of mitochondrial respiration in human skeletal muscle. J Physiol 2002;543:191-200.
18. Walsh B, Tonkonogi M, Saklin K. Effect of endurance training on oxidative and antioxidative function in human permeabilized muscle fibres. Pflugers Arch 2001;442:420-5.
19. Tonkonogi M, Harris B, Sahlin K. Mitochondrial oxidative function in human saponin-skinned muscle fibres: effects of prolonged exercise. J Physiol 1998;510:279-86.
20. Veksler VI, Kuznetsov AV, Sharov VG, Kapelko VI, Saks VA. Mitochondrial respiratory parameters in cardiac tissue: a novel method of assessment by using saponin-skinned fibers. Biochlm Biophys Acta 1987;892:191-6.
21. Wasserman K, Beaver WL, Whipp BJ. Gas exchange theory and the lactic acidosis (anaerobic) threshold. Circulation 1990;81 Suppl II: II14-30.
22. Saks VA, Veksler VI, Kuznetsov AV, et al. Permeabilized cell and skinned fiber techniques in studies of mitochondrial function in vivo. Mol Cell Biochem 1998;184:81-100.
23. De Sousa E, Veksler V, Minajeva A, et al. Subcellular creatine kinase alterations: implications in heart failure. Circ Res 1999;85:68-76.
24. Bigard AX, Boehm E, Veksler V, et al. Muscle unloading induces slow to fast transitions in myofibrillar but not mitochondrial properties: relevance to skeletal muscle abnormalities in heart failure. J Mol Cell Cardiol 1998;30:2391-401.
25. Agbulut O, Li Z, Mouly V, Butler-Browne GS. Analysis of skeletal and cardiac muscle from desmln knock-out and normal mice by high resolution separation of myosin heavy-chain isoforms. Biol Cell 1996;88:131-5.
26. Lampert E, Oyono-Enguelle S, Mettauer B, Freund H, Lonsdorfer J. Short endurance training improves lactate removal ability in patients with heart transplants. Med Sci Sports Exerc 1996;28:801-7.
27. Dunn SE, Burns JL, Michel RN. Calcineurin is required for skeletal muscle hypertrophy. J Biol Chem 1999;274:21908-12.
28. Bigard X, Sanchez H, Zoll J, et al. Calcineurin co-regulates contractile and metabolic components of slow muscle phenotype. J Biol Chem 2000;275:19653-60.
29. Rowell LB. Human cardiovascular adjustments to exercise and thermal stress. Physiol Rev 1974;54:75-159.
30. Veksler VI, Kuznetsov AV, Anflous K, et al. Muscle creatine kinase-deficient mice. II. Cardiac and skeletal muscles exhibit tissue-specific adaptation of the mitochondrial function. J Biol Chem 1995;270:19921-9.
31. Booth FW, Thomason DB. Molecular and cellular adaptation of muscle in response to exercise: perspectives of various models. Physiol Rev 1991;71:541-85.
32. Mettauer B, Lampert E, Charloux A, et al. Lung membrane diffusing capacity, heart failure, and heart transplantation. Am J Cardiol 1999;83:62-7.
33. Richard R, Verdier JC, Duvallet A, et al. Chronotropic competence in endurance trained heart transplant recipients: heart rate is not a limiting factor for exercise capacity. J Am Coll Cardiol 1999;33:192-7.
34. Hausberg M, Kisters K, Kosch M, Rahn KH, Barenbrock M. Flow-mediated vasodilation and distensibility of the brachial artery in renal allograft recipients. Kidney Int 1999;55:1104-10.
35. Hambrecht R, Fiehn E, Weigl C, et al. Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation 1998;98:2709-15.
36. Horber FF, Hoopeler H, Scheidegger JR, et al. Impact of physical training on the ultrastructure of midthigh muscle in normal subjects and in patients treated with glucocorticoids. J Clin Invest 1987;79:1181-90.
37. Renlund DG, Taylor DO, Ensley RD, et al. Exercise capacity after heart transplantation: influence of donor and recipient characteristics. J Heart Lung Transplant 1996;15:16-24.