Correlations between concentrations of interleukin-12 and interleukin-13 and lymphocyte subsets in the follicular fluid of women with and without polycystic ovary syndrome

Fertility and Sterility

Volumn 79, Issue 6, 2003, Pages 1365-1372

  Gallinelli, Andrea ^a   Ciaccio, Ivan ^a   Giannella, Luca ^a   Salvatori, Michela ^a   Marsella, Tiziana ^a   Volpe, Annibale ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Cytokines; Immunity; IVF embryo transfer; Polycystic ovarian syndrome; Pregnancy rate

Indexed keywords

ANDROSTENEDIONE; INTERLEUKIN 12; INTERLEUKIN 13; TESTOSTERONE;

ADULT; ARTICLE; BLOOD SAMPLING; CELL COUNT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; EMBRYO TRANSFER; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; HELPER CELL; HUMAN; LYMPHOCYTE SUBPOPULATION; MAJOR CLINICAL STUDY; OVARY FOLLICLE FLUID; OVARY POLYCYSTIC DISEASE; OVULATION; PREGNANCY RATE; PRIORITY JOURNAL; PROTEIN DETERMINATION; SUPPRESSOR CELL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

EID: 0037497971     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(03)00344-3     Document Type: Article

References (46)

1. Ehrmann D.A., Barnes R.B., Rosenfield R.L. Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion. Endocrinol Rev. 16:1995;322-353.
2. Franks S. Polycystic ovary syndrome N Engl J Med. 333:1995;853-861.
3. Franks S., White D., Gilling-Smith C., Carey A., Waterworth D., Williamson R. Hypersecretion of androgens by polycystic ovaries the role of genetic factors in the regulation of cytochrome P450c17α Baillière's Clin Endocrinol Metab. 10:1996;193-203.
4. Gharani N, Waterworth DM, Batty S, White D, Gilling-Smith C, Conway GS et al. Association of the steroid synthesis gene CYP11a with polycystic ovary syndrome and hyperandrogenism. Hum Mol Genet 1997;6:397-403.
5. Dunaif A. Insulin resistance and the polycystic ovary syndrome mechanism and implications for pathogenesis . Endocr Rev. 18:1997;774-800.
6. Legro R.S. The genetics of polycystic ovary syndrome. Am J Med. 98:1995;9-16.
7. Wichenheisser J.K., Quinn P.G., Nelson V.L., Legro R.S., Strauss J.F., McAllister J. Differential activity of the cytochrome P450 17α-hydroxylase and steroidogenic acute regulatory protein gene promoters in normal and polycystic ovary syndrome theca cells. J Clin Endocrinol Metab. 85:2000;2304-2311.
8. Carey A.H., Chan K.L., Short F., White D.M., Williamson R., Franks S. Evidence for a single gene effect in polycystic ovaries and male pattern baldness. Clin Endocrinol. 38:1993;653-658.
9. Barreca A., Del Monte P., Ponzani P., Artini P.G., Genazzani A.R., Minuto F. Intrafollicular insulin-like growth factor-II levels in normally ovulating women and in patients with polycystic ovary syndrome. Fertil Steril. 65:1996;739-745.
10. Homburg R., Berkowitz D., Levy T., Feldberg D., Ashkenazi J., Ben-Rafael Z. In vitro fertilization and embryo transfer for the treatment of infertility associated with polycystic ovary syndrome. Fertil Steril. 60:1993;858-863.
11. Luborsky J.L., Shatavi S., Adamczyk P., Chiong C., Llanes B., Lafniztzegger J., et al. Polycystic ovary syndrome and ovarian autoimmunity-assessment of ovarian antibodies by EIA. J Reprod Immunol. 42:1999;79-84.
12. Kaaijk E.M., Sasano H., Suzuki T., Beek J.F., van-Der-Veen F. Distribution of steroidogenic enzymes involved in androgen synthesis in polycystic ovaries an immunohistochemical study . Mol Hum Reprod. 6:2000;443-447.
13. Loukides J.A., Loy R.A., Edwards R., Honig J., Visintin I., Polan M.L. Human follicular fluids contain tissue macrophages. J Clin Endocrinol Metab. 71:1990;1363-1367.
14. Calogero A.E., Nicoletti F., Palumbo M.A., Burrello N., Di-Mauro M., Lunetta M., et al. Macrophage-derived cytokines in the follicular fluids of women with infertility due to immunological causes. Elevated levels of interleukin 6 and low levels of granulocyte-macrophage colony-stimulating factor. Cytokine. 10:1998;814-818.
15. Droesch K., Fulgham D.L., Liu H.C., Rosenwaks Z., Alexander N.J. Distribution of T-cell subsets in follicular fluid. Fertil Steril. 50:1988;618-621.
16. Garcia-Velasco J.A., Arici A. Chemokines and human reproduction. Fertil Steril. 71:1999;983-993.
17. Naz R.K., Butler A. Interleukins-6 and -8 levels in sera and cervical mucus of fertile, idiopathic infertile, and immunoinfertile women implication in infertility . Am J Reprod Immunol. 35:1996;534-540.
18. Barak V., Yanai P., Treves A.J., Roisman I., Simon A., Laufer N., et al. Interleukin-1 local production and modulation of human granulosa luteal cells steroidogenesis . Fertil Steril. 58:1992;719-725.
19. Kennedy R.L., Jones T.H. Cytokines in endocrinology their roles in health and disease . J Endocrinol. 129:1991;167-168.
20. Arici A., Oral E., Bahtiyar O., Engin O., Seli E., Jones E. Leukemia inhibitory factor expression in man follicular fluid and ovarian cells. Hum Reprod. 12:1997;1233-1239.
21. Branisteanu I., Pijnenborg R., Spiessens C., Van-der-Auwera I., Keith J.C., Van-Assche F. Detection of immunoreactive interleukins-11 in human follicular fluid correlations with ovarian steroid, insulin-like growth factor I levels and follicular maturity . Fertil Steril. 67:1997;1054-1058.
22. Macciò A., Mantovani G., Turnu E., Artini P., Contu G., Volpe A. Evidence that granulosa cells inhibit interleukin-1 and interleukin-2 production from follicular lymphomonocytes. J Assist Reprod Genet. 10:1994;517-522.
23. Zeyneloglu H.B., Senturk L.M., Seli E., Bahtiyar O.M., Olive D.L., Arici A. The peritoneal fluid levels of interleukin-12 in women with endometriosis. Am J Reprod Immunol. 39:1998;152-156.
24. Somigliana E., Viganò P., Rossi G., Carinelli S., Vignali M., Panina-Bordignon P. Endometrial ability to implant in ectopic sites can be prevented by interleukin-12 in a murine model of endometriosis. Hum Reprod. 14:1999;2944-2950.
25. Buchanan J.M., Humphrey G.B., Metzger D.W. Biological properties and potential clinical applications of interleukin 12. Int J Paed Hematol Oncol. 3:1996;123-131.
26. Zurawski G., de Vries J.E. Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells but not on T cells. Immunol Today. 15:1994;19-26.
27. Blais Y., Gingras S., Haagensen D.E., Labrie F., Simard J. Interleukin-4 and interleukin-13 inhibit estrogen-induced breast cancer cell proliferation and stimulate GCDFP-15 expression in human breast cancer cells. Mol Cell Endocrinol. 121:1996;11-18.
28. McLaren J, Dealtry G, Prentice A, Charnock-Jones DS, Smith SK. Decreased levels of the point regulator of monocyte/macrophage activation, interleukin-13, in the peritoneal fluid of patients with endometriosis. Hum Reprod 1997;12:1307-10.
29. Genazzani A.D., Petraglia F., Benatti R., Montanini V., Algeri I., Volpe A., et al. Luteinizing hormone (LH) secretory burst duration is independent from LH, prolactin, or gonadal steroid plasma levels in amenorrheic women. J Clin Endocrinol Metab. 72:1991;1220-1225.
30. Genazzani AD, Rodbard D, Forti G, Petraglia F, Baraghini G-F, Genazzani AR. Estimation of instantaneous secretory rate of luteinizing hormone in women during the menstrual cycle and in men. Clin Endocrinol 1990;32:573-81.
31. Ferriman DM, Gallwey JD. Clinical assessment of body hair growth in women. J Clin Endocrinol Metab 1961;60:1440.
32. Ciampelli M., Fulghesu A.M., Cucinelli F., Pavone V., Ronsisvalle E., Guido M., et al. Impact of insulin and body mass index on metabolic and endocrine variables in polycystic ovary syndrome. Metabolism. 48:1999;167-172.
33. Geva E., Amit A., Lerner-Geva L., Azem F., Yovel I., Lessig J.B. Autoimmune disorders another possible cause for in-vitro fertilization and embryo transfer failure . Hum Reprod. 10:1995;2560-2563.
34. Garcia J.E., Jones G.S., Acosta A.A., Wright G. Correlation of human menopausal gonadotropin/human chorionic gonadotropin stimulation and oocyte quality in an in vitro fertilization program. Fertil Steril. 41:1983;196-201.
35. Dor J., Rudak E., Mashiach S., Nebel L., Serr D.M., Goldman B. Periovulatory 17β-estradiol changes and embryo morphologic features in conception and nonconceptional cycles after human in vitro fertilization. Fertil Steril. 45:1986;63-66.
36. Lachapelle M.H., Hemmings R., Roy D.C., Falcone T., Miron P. Flow cytometric evaluation of leukocytes subpopulation in the follicular fluid of infertile patients. Fertil Steril. 65:1996;1135-1140.
37. Nicholson J.K.A., Hubbard M., Jones B.M. Use of CD45 fluorescence and side-scatter characteristics for gating lymphocytes when using the whole blood lysis procedure and flow cytometry. Cytometry. 26:1996;16-21.
38. Melamed M.R., Lindmo T., Mendelsohn M.L. Flow-cytometry and sorting. 2nd rev. ed. 1990;Wiley-Liss, New York.
39. Tomkinson B.E., Wagner D.K., Nelson D.L., Sullivan J.L. Activated lymphocytes during acute Epstein-Barr virus infection. Immunol. 139:1987;3802-3807.
40. Naz R.K., Evans L. Presence and modulation of interleukin-12 in seminal plasma of fertile and infertile men. J Androl. 19:1998;302-307.
41. Volpe A., Coukos G., D'Ambrogio G., Artini P., Genazzani A.R. Follicular fluid steroid and epidermal growth factor content, and in vitro estrogen release by granulosa-luteal cells from patients with polycystic ovaries in an IVF/ET program. Eur J Obstet Gynecol Reprod Biol. 42:1991;195-199.
42. Coskun S., Uzumcu M., Jaroudi K., Hollanders J.M., Parhar R.S., Sedairy S.T. Presence of leukemia inhibitory factor and interleukin-12 in human follicular fluid during follicular growth. Am J Reprod Immunol. 40:1998;13-18.
43. Gazvani M.R., Bates M., Vince G., Christmas S., Lewis-Jones D.I., Kingsland C. Follicular fluid concentrations of interleukin-12 and interleukin-8 in IVF cycles. Fertil Steril. 74:2000;953-958.
44. Bennet W.A., Lagoo-Deenadayalan S., Whitworth N.S., Stopple J.A., Barber W.H., Hale E., et al. First-trimester human chorionic villi express both immunoregulatory and inflammatory cytokines a role for interleukin-10 in regulating the cytokine network of pregnancy . Am J Reprod Immunol. 41:1999;70-78.
45. Srivastava M.D., Lippes J., Srivastava B.I. Cytokines of the human reproductive tract. Am J Reprod Immunol. 36:1996;157-166.
46. Wang L.J., Norman R.J. Concentrations of immunoreactive interleukin-1 and interleukin-2 in human preovulatory follicular fluid. Hum Reprod. 7:1992;147-150.