The embryolethality of lipopolysaccharide in CD-1 and metallothionein I-II null mice: Lack of a role for induced zinc deficiency or metallothionein induction

Toxicological Sciences

Volumn 73, Issue 2, 2003, Pages 442-447

  Leazer, Tyra M ^a,b   Daston, George P ^c   Keen, Carl L ^d   Rogers, John M ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c PROCTER AND GAMBLE COMPANY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Embryolethality; Lipopolysaccharide; Metallothionein; Metallothionein null mice; Zinc deficiency

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; METALLOTHIONEIN; TUMOR NECROSIS FACTOR ALPHA; ZINC;

ACUTE PHASE RESPONSE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DIET SUPPLEMENTATION; DISEASE EXACERBATION; DOSE RESPONSE; EMBRYO; EMBRYOTOXICITY; FEMALE; GESTATION PERIOD; HYPOTHESIS; INCIDENCE; LIVER; MEDICAL ASSESSMENT; MOUSE; MOUSE STRAIN; NONHUMAN; PREGNANCY; PROTEIN INDUCTION; SALMONELLA TYPHIMURIUM; TREATMENT OUTCOME; WILD TYPE; ZINC DEFICIENCY;

ACUTE-PHASE REACTION; ANIMALS; DRUG SYNERGISM; FEMALE; FETAL DEATH; GESTATIONAL AGE; INJECTIONS, INTRAPERITONEAL; LIPOPOLYSACCHARIDES; LIVER; METALLOTHIONEIN; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; PREGNANCY; SALMONELLA TYPHIMURIUM; SPECIES SPECIFICITY; ZINC;

ANIMALIA; BACTERIA (MICROORGANISMS); SALMONELLA TYPHIMURIUM; VERTEBRATA;

EID: 0037497139     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfg088     Document Type: Article

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