HER2 oncogene amplification in extramammary Paget's disease

Histopathology

Volumn 42, Issue 6, 2003, Pages 575-579

  Tanskanen, Maarit ^a,d   Jahkola, T ^b   Asko Seljavaara, S ^b   Jalkanen, J ^b   Isola, J ^c  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c UNIVERSITY OF TAMPERE   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

Author keywords

C erbB 2 protein; Extramammary Paget's disease; HER2 gene amplification

Indexed keywords

ONCOPROTEIN;

ADULT; AGED; ARTICLE; CANCER IMMUNOTHERAPY; CHROMOGENIC IN SITU HYBRIDIZATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; ONCOGENE NEU; PAGET SKIN DISEASE; PRIORITY JOURNAL;

AGED; BREAST NEOPLASMS; FEMALE; GENE AMPLIFICATION; GENES, ERBB-2; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MIDDLE AGED; PAGET'S DISEASE, EXTRAMAMMARY; PAGET'S DISEASE, MAMMARY; RECEPTOR, ERBB-2; SKIN NEOPLASMS;

EID: 0037495264     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2559.2003.01648.x     Document Type: Article

References (21)

1. Kirkham N. Extramammary Paget's disease. In Elder D, Eleniatsas R, Jaworsky C, Johnson B Jr eds. Lever's histopathology of the skin. 8th edn. Philadelphia: Lippincott-Raven, 1997: 740-742.
2. Mazouijian G, PInkus GS, Haagensen DE Jr. Extramammary Paget's disease - evidence for an apocrine origin. An immunoperoxidase study of gross cystic disease fluid protein-15, carcinoembryonic antigen (CEA). and keratin proteins. Am. J. Surg. Pathol. 1984: 8; 43-50.
3. Tsuji T. Mammary and extramammary Paget's disease. Expression of Ca15-3, Ka-93, Ca19-9 and CD44 in Paget cells and adjacent normal skin. Br. J. Dermatol. 1995: 132; 7-13.
4. Teixeira MR, Kristensen GB, Abeler VM, Heim S. Karyotypic findings in tumors of the vulva and vagina. Cancer Genet. Cytogenet. 1999: 111; 87-91.
5. Lammie GA, Barnes DM, Millis RR, Gullick WJ. An immunohistochemical study of the presence of c-erbB-2 protein in Paget's disease. Histopathology 1989: 15; 505-514.
6. Keatings L, Sinclair J, Wright C et al. C-erbB-2 oncoprotein expression in mammary and extramammary Paget's disease: an immunohistochemical study. Histopathology 1990: 17; 243-247.
7. Meissner K, Riviere A, Haupt G, Loning T. Study of neu-protein expression in mammary Paget's disease with and without underlying breast carcinoma and in extramammary Paget's disease. Am. J. Pathol. 1990: 137; 1305-1309.
8. Fu W, Lobocki CA, Silberberg BK. Molecular markers in Paget's disease of the breast. J. Surg. Oncol. 2001: 77; 171-180.
9. Wolber RA, Dypuis BA, Wick MR. Expression of c-erbB-2 oncoprotein in mammary and extramammary Paget's disease. Am. J. Clin. Pathol. 1991: 96; 243-247.
10. Schgelfout VR, Coene ED, Delaey B, Thys S, Page DL, DePotter CR. Pathogenesis of Paget's disease: epidermal heregulin-alpha. motility factor and the HER receptor family. J. Natl Cancer Inst. 2000: 92; 622-628.
11. Nishi M, Yoshida H, Setoyama M, Tashiro M. Immunohistochemical study of c-erbB-2 oncoprotein expression in extramammary Paget's disease. Dermatology 1994: 188; 100-102.
12. Scheistroen M, Trope C, Kaern J, Pettersen EO, Alfsen GC, Nesland JM. DNA ploidy and expression of p53 and C-erbB-2 in extramammary Paget's disease of the vulva. Gynecol. Oncol. 1997: 64; 88-92.
13. Ross JS, Fletcher JA. HER-2/neu (c-erb-B2) gene and protein in breast cancer. Am. J. Clin. Pathol. 1999: 112; 53-67.
14. Takata M, Fujimoto A, Aoki H, Hatta N, Ooi A, Takehara K. ErbB-2 overexpression but no activation of beta-catenin gene in extramammary Paget's disease. J. Invest. Dermatol. 1999: 113; 258-262.
15. Tanner M, Gancberg D, DiLeo A et al. Chromogene in situ hybridization. A practical alternative for fluorescence in situ hybridization to detect HER-2/neu oncogene amplification in archival breast cancer samples. Am. J. Pathol. 2000; 157; 1467-1472.
16. Kodama S, Kaneko T, Saito M, Yoshiya N, Honma S, Tanaka K. A clinicopathologic study of 30 patients with Paget's disease of the vulva. Gynecol. Oncol. 1995: 56; 63-70.
17. Sarmiento JM, Wolff BG, Burgart LJ, Frizelle FA, Ilstrup DM. Paget's disease of the perianal region - an aggressive disease? Dis. Colon Rectum 1997: 40; 1187-1194.
18. Yugueros P, Keeney GL, Bite U. Paget's disease of the groin: report of seven cases. Plast. Reconstr. Surg. 1997: 100; 336-339.
19. Curtinn JP, Rubin SC, Jones WB, Hoskins WJ, Lewis JL Jr. Paget's disease of the vulva. Gynecol. Oncol. 1990: 39; 374-377.
20. Hatoko M, Okazaki T, Tada H et al. Vulvar reconstruction using rectus abdominis musculocutaneous flap transfer with secondary liposuction in extramammary Paget's disease. Ann. Plast. Surg. 1997: 38; 179-183.
21. Slamon DJ, Leyland-Jones B, Shak S et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N. Engl. J. Med. 2001: 344; 783-792.