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Volumn 29, Issue 6, 2003, Pages 989-994

Nicotinamide increases systemic vascular resistance in ovine endotoxemia

Author keywords

Endotoxin; Inflammation; Liver injury; PARP; Sheep; Vasoconstriction

Indexed keywords

ENDOTOXIN; GAMMA GLUTAMYLTRANSFERASE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ARGININE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

EID: 0037490099     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-003-1738-7     Document Type: Article
Times cited : (5)

References (32)
  • 1
    • 0030000690 scopus 로고    scopus 로고
    • DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite
    • Szabo C, Zingarelli B, O'Connor M, Salzman AL (1996) DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite. Proc Natl Acad Sci USA 93:1753-1758
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1753-1758
    • Szabo, C.1    Zingarelli, B.2    O'Connor, M.3    Salzman, A.L.4
  • 2
    • 0025994095 scopus 로고
    • Oxidant-induced cytotoxicity: A challenge for metabolic modulation
    • Berger NA (1991) Oxidant-induced cytotoxicity: a challenge for metabolic modulation. Am J Respir Cell Mol Biol 4:1-3
    • (1991) Am J Respir Cell Mol Biol , vol.4 , pp. 1-3
    • Berger, N.A.1
  • 3
    • 0036733355 scopus 로고    scopus 로고
    • The therapeutic potential of poly(ADP-Ribose) polymerase inhibitors
    • Virag L, Szabo C (2002) The therapeutic potential of poly(ADP-Ribose) polymerase inhibitors. Pharmacol Rev 54:375-429
    • (2002) Pharmacol Rev , vol.54 , pp. 375-429
    • Virag, L.1    Szabo, C.2
  • 4
    • 0027947675 scopus 로고
    • New insights into the regulation of inducible nitric oxide synthesis
    • Morris SM Jr, Billiar TR (1994) New insights into the regulation of inducible nitric oxide synthesis. Am J Physiol 266:E829-839
    • (1994) Am J Physiol , vol.266
    • Morris S.M., Jr.1    Billiar, T.R.2
  • 5
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA (1990) Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 87:1620-1624
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 6
    • 0028294246 scopus 로고
    • Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity
    • Zhang J, Dawson VL, Dawson TM, Snyder SH (1994) Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 263:687-689
    • (1994) Science , vol.263 , pp. 687-689
    • Zhang, J.1    Dawson, V.L.2    Dawson, T.M.3    Snyder, S.H.4
  • 7
    • 0029934194 scopus 로고    scopus 로고
    • Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite
    • Szabo C, Zingarelli B, Salzman AL (1996) Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite. Circ Res 78:1051-1063
    • (1996) Circ Res , vol.78 , pp. 1051-1063
    • Szabo, C.1    Zingarelli, B.2    Salzman, A.L.3
  • 8
    • 0030026515 scopus 로고    scopus 로고
    • Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide
    • Zingarelli B, O'Connor M, Wong H, Salzman AL, Szabo C (1996) Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide. J Immunol 156:350-358
    • (1996) J Immunol , vol.156 , pp. 350-358
    • Zingarelli, B.1    O'Connor, M.2    Wong, H.3    Salzman, A.L.4    Szabo, C.5
  • 9
    • 0030124761 scopus 로고    scopus 로고
    • Protective effects of nicotinamide against nitric oxide-mediated delayed vascular failure in endotoxic shock: Potential involvement of polyADP ribosyl synthetase
    • Zingarelli B, Salzman AL, Szabo C (1996) Protective effects of nicotinamide against nitric oxide-mediated delayed vascular failure in endotoxic shock: potential involvement of polyADP ribosyl synthetase. Shock 5:258-264
    • (1996) Shock , vol.5 , pp. 258-264
    • Zingarelli, B.1    Salzman, A.L.2    Szabo, C.3
  • 10
    • 0030854951 scopus 로고    scopus 로고
    • Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite
    • Szabo C, Cuzzocrea S, Zingarelli B, O'Connor M, Salzman AL (1997) Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. J Clin Invest 100:723-735
    • (1997) J Clin Invest , vol.100 , pp. 723-735
    • Szabo, C.1    Cuzzocrea, S.2    Zingarelli, B.3    O'Connor, M.4    Salzman, A.L.5
  • 11
    • 0032059832 scopus 로고    scopus 로고
    • Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock
    • Szabo C (1998) Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock. Shock 9:341-344
    • (1998) Shock , vol.9 , pp. 341-344
    • Szabo, C.1
  • 12
    • 0032196891 scopus 로고    scopus 로고
    • 3-Aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase, improves hemodynamics and prolongs survival in a porcine model of hemorrhagic shock
    • Szabo A, Hake P, Salzman AL, Szabo C (1998) 3-Aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase, improves hemodynamics and prolongs survival in a porcine model of hemorrhagic shock. Shock 10:347-353
    • (1998) Shock , vol.10 , pp. 347-353
    • Szabo, A.1    Hake, P.2    Salzman, A.L.3    Szabo, C.4
  • 15
    • 0029926477 scopus 로고    scopus 로고
    • L-arginine augments nitric oxide production and mesenteric blood flow in ovine endotoxemia
    • Allman KG, Stoddart AP, Kennedy MM, Young JD (1996) L-arginine augments nitric oxide production and mesenteric blood flow in ovine endotoxemia. Am J Physiol 271:H1296-1301
    • (1996) Am J Physiol , vol.271
    • Allman, K.G.1    Stoddart, A.P.2    Kennedy, M.M.3    Young, J.D.4
  • 16
    • 0032577469 scopus 로고    scopus 로고
    • Role of poly(ADP-ribose)synthetase in inflammation
    • Szabo C (1998) Role of poly(ADP-ribose)synthetase in inflammation. Eur J Pharmacol 350:1-19
    • (1998) Eur J Pharmacol , vol.350 , pp. 1-19
    • Szabo, C.1
  • 17
    • 0026601666 scopus 로고
    • Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP- ribosyl)transferase
    • Banasik M, Komura H, Shimoyama M, Ueda K (1992) Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP- ribosyl)transferase. J Biol Chem 267:1569-1575
    • (1992) J Biol Chem , vol.267 , pp. 1569-1575
    • Banasik, M.1    Komura, H.2    Shimoyama, M.3    Ueda, K.4
  • 18
    • 0034870585 scopus 로고    scopus 로고
    • Suppression of poly (ADP-ribose) polymerase activation by 3-aminobenzamide in a rat model of myocardial infarction: Long-term morphological and functional consequences
    • Liaudet L, Szabo E, Timashpolsky L, Virag L, Cziraki A, Szabo C (2001) Suppression of poly (ADP-ribose) polymerase activation by 3-aminobenzamide in a rat model of myocardial infarction: long-term morphological and functional consequences. Br J Pharmacol 133:1424-1430
    • (2001) Br J Pharmacol , vol.133 , pp. 1424-1430
    • Liaudet, L.1    Szabo, E.2    Timashpolsky, L.3    Virag, L.4    Cziraki, A.5    Szabo, C.6
  • 19
    • 0024240517 scopus 로고
    • Mechanisms of nicotinamide and thymidine protection from alloxan and streptozocin toxicity
    • LeDoux SP, Hall CR, Forbes PM, Patton NJ, Wilson GL (1988) Mechanisms of nicotinamide and thymidine protection from alloxan and streptozocin toxicity. Diabetes 37:1015-1019
    • (1988) Diabetes , vol.37 , pp. 1015-1019
    • LeDoux, S.P.1    Hall, C.R.2    Forbes, P.M.3    Patton, N.J.4    Wilson, G.L.5
  • 20
    • 0032113022 scopus 로고    scopus 로고
    • Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin
    • Wray GM, Hinds CJ, Thiemermann C (1998) Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin. Shock 10:13-19
    • (1998) Shock , vol.10 , pp. 13-19
    • Wray, G.M.1    Hinds, C.J.2    Thiemermann, C.3
  • 22
    • 0026437804 scopus 로고
    • Induction of nitric oxide synthase in L929 cells by tumour-necrosis factor alpha is prevented by inhibitors of poly(ADP-ribose) polymerase
    • Hauschildt S, Scheipers P, Bessler WG, Mulsch A (1992) Induction of nitric oxide synthase in L929 cells by tumour-necrosis factor alpha is prevented by inhibitors of poly(ADP-ribose) polymerase. Biochem J 288:255-600
    • (1992) Biochem J , vol.288 , pp. 255-600
    • Hauschildt, S.1    Scheipers, P.2    Bessler, W.G.3    Mulsch, A.4
  • 23
    • 0345628001 scopus 로고    scopus 로고
    • Inhibitors of ADP-ribosylation impair inducible nitric oxide synthase gene transcription through inhibition of NF kappa B activation
    • Le Page C, Sanceau J, Drapier JC, Wietzerbin J (1998) Inhibitors of ADP-ribosylation impair inducible nitric oxide synthase gene transcription through inhibition of NF kappa B activation. Biochem Biophys Res Commun 243:451-457
    • (1998) Biochem Biophys Res Commun , vol.243 , pp. 451-457
    • Le Page, C.1    Sanceau, J.2    Drapier, J.C.3    Wietzerbin, J.4
  • 24
    • 0028069673 scopus 로고
    • Nicotinamide inhibits nitric oxide sythase mRNA induction in activated macrophages
    • Pellat-Deceunyk K, Wietzerbin J, Drapier JC (1994) Nicotinamide inhibits nitric oxide sythase mRNA induction in activated macrophages. Biochem J 297:53-58
    • (1994) Biochem J , vol.297 , pp. 53-58
    • Pellat-Deceunyk, K.1    Wietzerbin, J.2    Drapier, J.C.3
  • 25
    • 0030992125 scopus 로고    scopus 로고
    • Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, and inhibitor of poly(ADP-ribose)synthetase and pleiotropic modifier of cellular signal pathways
    • Szabo C, Wong HR, Bauer PI, Kirsten E, O'Connor M, Zingarelli B, Mendeleyev J, Hasko G, Vizi ES, Salzman AL, Kun E (1997) Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, and inhibitor of poly(ADP-ribose)synthetase and pleiotropic modifier of cellular signal pathways. Int J Oncol 10:1093-1101
    • (1997) Int J Oncol , vol.10 , pp. 1093-1101
    • Szabo, C.1    Wong, H.R.2    Bauer, P.I.3    Kirsten, E.4    O'Connor, M.5    Zingarelli, B.6    Mendeleyev, J.7    Hasko, G.8    Vizi, E.S.9    Salzman, A.L.10    Kun, E.11
  • 27
    • 0036550855 scopus 로고    scopus 로고
    • Resistance to acute septic peritonitis in poly(ADP-ribose) polymerase-1-deficient mice
    • Soriano FG, Liaudet L, Szabo E, Virag L, Mabley JG, Pacher P, Szabo C (2002) Resistance to acute septic peritonitis in poly(ADP-ribose) polymerase-1-deficient mice. Shock 17:286-292
    • (2002) Shock , vol.17 , pp. 286-292
    • Soriano, F.G.1    Liaudet, L.2    Szabo, E.3    Virag, L.4    Mabley, J.G.5    Pacher, P.6    Szabo, C.7
  • 28
    • 0026341969 scopus 로고
    • DNA damage and cell death induced by 1,2-dibromo-3-chloropropane (DBCP) and structural analogs in monolayer culture of rat hepatocytes: 3-Aminobenzamide inhibits the toxicity of DBCP
    • Holme JA, Soderlund EJ, Brunborg G, Lag M, Nelson SD, Dybing E (1991) DNA damage and cell death induced by 1,2-dibromo-3-chloropropane (DBCP) and structural analogs in monolayer culture of rat hepatocytes: 3-aminobenzamide inhibits the toxicity of DBCP. Cell Biol Toxicol 7:413-432
    • (1991) Cell Biol Toxicol , vol.7 , pp. 413-432
    • Holme, J.A.1    Soderlund, E.J.2    Brunborg, G.3    Lag, M.4    Nelson, S.D.5    Dybing, E.6
  • 29
    • 0342526809 scopus 로고    scopus 로고
    • The influence of antagonists of poly(ADP-ribose) metabolism on acetaminophen hepatotoxicity
    • Kroger H, Ehrlich W, Klewer M, Gratz R, Dietrich A, Miesel R (1996) The influence of antagonists of poly(ADP-ribose) metabolism on acetaminophen hepatotoxicity. Gen Pharmacol 27:167-170
    • (1996) Gen Pharmacol , vol.27 , pp. 167-170
    • Kroger, H.1    Ehrlich, W.2    Klewer, M.3    Gratz, R.4    Dietrich, A.5    Miesel, R.6
  • 31
    • 0032545762 scopus 로고    scopus 로고
    • Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP- ribose) synthase in a carrageenan-induced model of local inflammation
    • Cuzzocrea S, Zingarelli B, Gilad E, Hake P, Salzman AL, Szabo C (1998) Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP- ribose) synthase in a carrageenan-induced model of local inflammation. Eur J Pharmacol 342:67-76
    • (1998) Eur J Pharmacol , vol.342 , pp. 67-76
    • Cuzzocrea, S.1    Zingarelli, B.2    Gilad, E.3    Hake, P.4    Salzman, A.L.5    Szabo, C.6
  • 32
    • 0027203815 scopus 로고
    • Differing effects of the inhibition of poly(ADP-ribose) polymerase on the course of oxidative cell injury in hepatocytes and fibroblasts
    • Yamamoto K, Tsukidate K, Farber JL (1993) Differing effects of the inhibition of poly(ADP-ribose) polymerase on the course of oxidative cell injury in hepatocytes and fibroblasts. Biochem Pharmacol 46:483-491
    • (1993) Biochem Pharmacol , vol.46 , pp. 483-491
    • Yamamoto, K.1    Tsukidate, K.2    Farber, J.L.3


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