SCOPUS 정보 검색 플랫폼

Volumn 8, Issue 12, 2002, Pages 337-349

ADME evaluation in drug discovery: 1. Applications of genetic algorithms to the prediction of blood-brain partitioning of a large set of drugs

(2) Hou, Tingjun a Xu, Xiaojie a

a PEKING UNIVERSITY (China)

Author keywords

ADME; Blood brain partitioning; Genetic algorithm; QSPR

Indexed keywords

CENTRAL NERVOUS SYSTEM AGENTS; CHEMICAL COMPOUND; OCTANE; SOLVENT; WATER;

ARTICLE; BLOOD BRAIN BARRIER; CHEMICAL STRUCTURE; CORRELATION COEFFICIENT; DRUG PENETRATION; GENETIC ALGORITHM; HUMAN; MOLECULAR EVOLUTION; MOLECULAR MODEL; PARTITION COEFFICIENT; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE PROPERTY RELATION; STATISTICAL MODEL; STATISTICAL SIGNIFICANCE; SURFACE CHARGE; SURFACE PROPERTY;

ALGORITHMS; ANIMALS; BLOOD-BRAIN BARRIER; LINEAR MODELS; MODELS, GENETIC; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037480602 PISSN: 16102940 EISSN: None Source Type: Journal
DOI: 10.1007/S00894-002-0101-1 Document Type: Article

Times cited : (81)

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