Effects of fructose-1,6-bisphosphate on morphological and functional neuronal integrity in rat hippocampal slices during energy deprivation

Neuroscience

Volumn 116, Issue 2, 2003, Pages 465-475

  Izumi, Y ^a   Benz, A M ^a   Katsuki, H ^a   Matsukawa, M ^a   Clifford, D B ^a   Zorumski, C F ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dizocilpine; Energy metabolism; Fructose 1,6 bisphospate; Ischemia; N methyl D aspartate receptors; Pyruvate

Indexed keywords

ADENOSINE TRIPHOSPHATE; DIZOCILPINE; FRUCTOSE 1,6 BISPHOSPHATE; GLUCOSE; IODOACETIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PYRUVIC ACID;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL STRUCTURE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG ACTIVITY; ENERGY METABOLISM; GLYCOLYSIS; HIPPOCAMPUS; NERVE CELL DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SYNAPTIC TRANSMISSION;

EID: 0037474149     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00661-9     Document Type: Article

References (47)

1. Beaughard M., Poignet H., Michelin M.T., Lecoin G., Massingham R. Lack of efficacy of MK-801, a non-competitive antagonist of NMDA receptors, on behavioral and neuronal abnormalities induced by transient forebrain ischaemia in the conscious rat. Seylaz I.J., MacKenzie E.T. Neurotransmission and cerebrovascular function. 1989;457-460 Elsevier Science, Amsterdam.
2. Benz A.M., Izumi Y., Zorumski C.F. Alternative energy substrates for morphological and functional integrity during glucose deprivation. Soc Neurosci Abstracts. 24:1998;1605.
3. Bickler P.E., Buck L.T. Effects of fructose-1,6-bisphosphate on glutamate release and ATP loss from rat brain slices during hypoxia. J Neurochem. 67:1996;1463-1468.
4. Bickler P.E., Kelleher J.A. Fructose-1,6-bisphosphate stabilizes brain intracellular calcium during hypoxia in rats. Stroke. 23:1992;1617-1622.
5. Cannella D.M., Kapp J.P., Munschauer F.E., Markov A.K., Shucard D.W. Cerebral resuscitation with succinate and fructose-1,6-diphosphate. Surg Neurol. 31:1989;177-182.
6. Didlake R., Kirchner K.A., Lewin J., Bower J.D., Markov A.K. Attenuation of ischemic renal injury with fructose 1,6-diphosphate. J Surg Res. 47:1989;220-226.
7. Dietrich W.D., Lin B., Globus M.Y., Green E.J., Ginsberg M.D., Busto R. Effect of delayed MK-801 (Dizocilpine) treatment with or without immediate postischemic hypothermia on chronic neuronal survival after global forebrain ischemia in rats. J Cereb Blood Flow Metab. 15:1995;960-968.
8. 2+ modulation with fructose-1,6-bisphosphate during in vitro hypoxia-ischemia involves phospholipase C-dependent signaling. Brain Res. 917:2001;158-166.
9. Espanol M.T., Litt L., Hasegawa K., Chang L.H., Macdonald J.M., Gregory G., James T.L., Chan P.H. Fructose-1,6-bisphosphate preserves adenosine triphosphate but not intracellular pH during hypoxia in respiring neonatal rat brain slices. Anesthesiology. 88:1998;461-472.
10. Fairas L.A., Willis M., Gregory G.A. The effects of fructose 1-6 diphosphate, glucose and saline on cardiac resuscitation. Anesthesiology. 65:1986;595-601.
11. Fairas L.A., Sun J., Markov A.K. Improved brain metabolism with fructose 1-6 diphosphate during insulin-induced hypoglycemic coma. Am J Med Sci. 297:1989;294-299.
12. Farias L.A., Smith E.E., Markov A.K. Prevention of ischemic-hypoxic brain injury and death in rabbits with fructose-1,6-diphosphate. Stroke. 21:1990;606-613.
13. Fleischer J.E., Tateishi A., Drummond J.C., Scheller M.S., Grafe M.R., Zornow M.H., Shearman G.T., Shapiro H.M. MK-801, an excitatory amino acid antagonist, does not improve neurologic outcome following cardiac arrest in cats. J Cereb Blood Flow Metab. 9:1989;795-804.
14. Fujii E., Kodama Y., Takahashi N., Roman C., Ferriero D., Gregory G., Parer J.T. Fructose-1,6-bisphosphate did not affect hippocampal neuronal damage caused by 10 min of complete umbilical cord occlusion in fetal sheep. Neurosci Lett. 309:2001;49-52.
15. Gobbel G.T., Chan T.Y., Gregory G.A., Chan P.H. Response of cerebral endothelial cells to hypoxia modification by fructose-1,6-bisphosphate but not glutamate receptor antagonists . Brain Res. 653:1994;23-30.
16. Gregory G.A., Welsh F.A., Yu A.C., Chan P.H. Fructose-1,6-bisphosphate reduces ATP loss from hypoxic astrocytes. Brain Res. 516:1990;310-312.
17. Hassinen I.E., Nuutinen E.M., Ito K., Nioka S., Lazzarino G., Giardina B., Chance B. Mechanisms of the effect of exogenous fructose 1,6-bisphosphate on myocardial energy metabolism. Circulation. 83:1991;584-593.
18. Izumi Y., Benz A.M., Zorumski C.F., Olney J.W. Effects of lactate and pyruvate on glucose deprivation in rat hippocampal slices. NeuroReport. 5:1994;617-620.
19. Izumi Y., Benz A.M., Clifford D.B., Zorumski C.F. Nitric oxide inhibitors attenuate ischemic degeneration in the CA1 region of rat hippocampal slices. Neurosci Lett. 210:1996;157-160.
20. Izumi Y., Benz A.M., Katsuki H., Zorumski C.F. Endogenous monocarboxylates sustain hippocampal synaptic function and morphological integrity during energy deprivation. J Neurosci. 17:1997;9448-9457.
21. Izumi Y., Ishii K., Katsuki H., Benz A.M., Zorumski C.F. β-Hydroxybutyrate fuels synaptic function during development histological and physiological evidence in rat hippocampal slices . J Clin Invest. 101:1998;1121-1132.
22. Jurica M.S., Mesecar A., Heath P.J., Shi W., Nowak T., Stoddard B.L. The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate. Structure. 6:1998;195-210.
23. Kanatani T., Mizuno K., Okada Y. Effects of glycolytic metabolites on preservation of high energy phosphate level and synaptic transmission in the granule cells of guinea pig hippocampal slices. Experientia. 51:1995;213-216.
24. Karaca M., Kilic E., Yazici B., Demir S., de L. Ischemic stroke in elderly patients treated with a free radical scavenger-glycolytic intermediate solution a preliminary pilot trial . Neurol Res. 24:2002;73-80.
25. Kelleher J.A., Chan P.H., Chan T.Y., Gregory G.A. Energy metabolism in hypoxic astrocytes protective mechanism of fructose 1,6-bisphosphate . Neurochem Res. 20:1995;785-792.
26. Kelleher J.A., Chan T.Y., Chan P.H., Gregory G.A. Protection of astrocytes by fructose 1,6-bisphosphate and citrate ameliorates neuronal injury under hypoxic conditions. Brain Res. 726:1996;167-173.
27. Kirtley M.E., McKay M. Fructose 1,6-diphosphate, a regulator of metabolism. Mol Cell Biochem. 18:1977;141-149.
28. Kuluz J.W., Gregory G.A., Han Y., Dietrich W.D., Schleien C.L. Fructose-1,6-bisphosphate reduces infarct volume after reversible middle cerebral artery occlusion in rats. Stroke. 24:1993;1576-1583.
29. LeBlanc M.H., Farias L.A., Evans O.B., Vig V., Smith E.E., Markov A.K. Fructose-1,6-bisphosphate, when given immediately before reoxygenation, or before injury, does not ameliorate hypoxic ischemic injury to the central nervous system in the newborn pig. Crit Care Med. 19:1991;75-83.
30. Liniger R., Popovic R., Sullivan B., Gregory G., Bickler P.E. Effects of neuroprotective cocktails on hippocampal neuron death in an in vitro model of cerebral ischemia. J Neurosurg Anesthesiol. 13:2001;19-25.
31. Markov A.K., Oglethorpe N., Grillis M., Neely W.A., Hellems H.K. Therapeutic action of fructose-1,6-diphosphate in traumatic shock. World J Surg. 7:1983;430-436.
32. Markov A.K. Hemodynamics and metabolic effects of fructose 1-6 diphosphate in ischemia and shock-experimental and clinical observations. Ann Emerg Med. 15:1986;1470-1477.
33. Michenfelder J.D., Lanier W.L., Scheithauer B.W., Perkins W.J., Shearman G.T., Milde J.H. Evaluation of the glutamate antagonist dizocilpine maleate (MK-801) on neurologic outcome in a canine model of complete cerebral ischemia correlation with hippocampal histopathology . Brain Res. 481:1989;228-234.
34. Nellgård B., Gustafson I., Wieloch T. Lack of protection by the N-methyl-D-aspartate receptor blocker Dizocilpine (MK-801) after transient severe cerebral ischemia in the rat. Anesthesiology. 75:1991;279-287.
35. Nishikawa K., MacIver B.M. Excitatory synaptic transmission mediated by NMDA receptors is more sensitive to isoflurane then are non-NMDA receptor-mediated responses. Anesthesiology. 92:2000;228-236.
36. Pfenninger E., Himmelseher S. Neuroprotective effects of ketamine of a cellular level. Anaesthesist. 46:(Suppl 1):1997;S47-S54.
37. Schurr A., West C.A., Rigor B.M. Lactate-supported synaptic function in the rat hippocampal slice preparation. Science. 240:1988;1326-1328.
38. Simon R.P., Schmidley J.W., Meldrum B.S., Swan J.H., Shapman A.G. Excitotoxic mechanisms in hypoglycemic hippocampal injury. Neuropathol Appl Neurobiol. 12:1986;567-576.
39. Sola A., Berrios M., Sheldon R.A., Ferriero D.M., Gregory G.A. Fructose-1,6-bisphosphate after hypoxic ischemic injury is protective to the neonatal rat brain. Brain Res. 741:(1-2):1996;294-299.
40. 2+] accumulation and ATP levels during oxygen and/or glucose deprivation in hippocampal slices of guinea pigs. Neurosci Lett. 227:1997;41-44.
41. Tortosa A., Rivera R., Ambrosio S., Bartrons R., Ferrer I. Fructose-1,6-bisphosphate fails to ameliorate delayed neuronal death in the CA1 area after transient forebrain ischaemia in gerbils. Neuropharmacology. 32:1993;1367-1371.
42. Trimarchi G.R., Arcadi F.A., De Luca R., Imperatore C., Santoro G., Trimarchi F., Costa G. Neuroprotective activity of fructose-1,6-bisphosphate following transient forebrain ischemia in the Mongolian gerbil. Jpn J Pharmacol. 62:1993;215-222.
43. Wieloch T. Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist. Science. 230:1985;681-683.
44. Williams R.J., Maus M., Stella N., Clowinski J., Premont J. Reduced glucose metabolism enhances the glutamate-evoked release of arachidonic acid from striatal neurons. Neuroscience. 74:1996; 461-446.
45. Zeevalk G.D., Nicklas W.J. Chemically induced hypoglycemia and anoxia relationship to glutamate receptor-mediated toxicity in retina . J Pharmacol Exp Ther. 253:1999;1285-1292.
46. Zhang J.N., Zhang F.M., Ma W.S., Forrester T. Protective effect of exogenous fructose-1,6-diphosphate in cardiogenic shock. Cardiovasc Res. 22:1988;927-932.
47. Zorumski C.F., Mennerick S., Izumi Y. Nitric oxide synthase characterization and functional analysis . Maines M.D. Methods in neurosciences. 1996;283-299 Academic Press, San Diego. Vol. 31.