Synthesis and potential antimetastatic activity of monovalent and divalent β-D-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-D-glucopyranosides

Carbohydrate Research

Volumn 338, Issue 3, 2003, Pages 207-217

  Li, Qing ^a   Su, Bin ^a   Li, Hui ^a   Meng, Xiang Bao ^a   Cai, Meng Shen ^a   Li, Zhong Jun ^a   Zhou, Rou Li ^a   Suo, Ta Lin ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Divalent; Metastasis; Monovalent; N Acetyllactosamine; Synthesis

Indexed keywords

SYNTHESIS (CHEMICAL); TUMORS;

GLYCOSYLATION;

CARBOHYDRATES;

3 OXAPENT 1,5 DIYLBIS(BETA DEXTRO GALACTOPYRANOSYL (1-4) 2 ACETAMIDO 2 DEOXY ALPHA DEXTRO GLUCOPYRANOSIDE); 3,6 DIOXAOCT 1,8 DIYLBIS(BETA DEXTRO GALACTOPYRANOSYL (1-4) 2 ACETAMIDO 2 DEOXY ALPHA DEXTRO GLUCOPYRANOSIDE); 8 HYDROXY 3,6 DIOXAOCTYL BETA DEXTRO GALACTOPYRANOSYL (1-4) 2 ACETAMINO 2 DEOXY BETA DEXTRO GLUCOPYRANOSIDE; ANTIMETASTATIC AGENT; CARBOHYDRATE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER INVASION; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; COVALENT BOND; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; GLYCOSYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; METASTASIS; METASTASIS INHIBITION; PRIORITY JOURNAL;

AMINO SUGARS; CELL ADHESION; CELL MOVEMENT; GLYCOSYLATION; HUMANS; LAMININ; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; TUMOR CELLS, CULTURED;

EID: 0037474017     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6215(02)00438-X     Document Type: Article

References (16)

1. Arumugham R.G., Hsieh T.C.-Y., Tanzer M.L., Laine R.A. Biochim. Biophys. Acta. 883:1986;112-126.
2. Yasuro S., Yukio H., Hanae K., Naoto S. Glycobiology. 7:1997;1201-1208.
3. Lemieux R.U., Ratcliffe R.M. Can. J. Chem. 57:1979;1244-1251.
4. Paulsen H., Lorentzen J.P. Carbohydr. Res. 133:1984;C1-C4.
5. Arnap J., Lönngren J. J. Chem. Soc. Perkin Trans. 1. 1981;2070-2074.
6. Li Q., Li H., Cai M.S., Li Z.J., Zhou R.L. Tetrahedron: Asymmetry. 10:1999;2675-2683.
7. Li Q., Li H., Su B., Meng X.B., Cai M.S., Li Z.J. J Peking Univ. (Health Sci.). 33:2001;270-273.
8. Kinzy W., Schmidt R.R. Carbohydr. Res. 164:1987;265-276.
9. Lemieux R.U., Driguez H. J. Am. Chem. Soc. 97:1975;4063-4068.
10. Lemieux R.U., Driguez H. J. Am. Chem. Soc. 97:1975;4069-4075.
11. Lonn H. Carbohydr. Res. 139:1985;105-113.
12. Rosen T., Lico I.M., Chu D.T.W. J. Org. Chem. 53:1988;1580-1582.
13. Jacquient J.-C. Carbohydr. Res. 199:1990;153-181.
14. Chen X.Q., Yang X.O., Pan G.Z., Zhu F. Aizheng. 17:1998;477-478.
15. Albini A., Iwamoto Y., Kleinmen H.K., Martin G.R., Aaronson S.A., Kozlowski J.M., McEwan R.N. Cancer Res. 47:1987;3239-3245.
16. Lu Y.Y., Zhou R.L. Chin. J. Oncol. 22:2000;287-289.