Prediction of pathogenic mutations in patients with early-onset breast cancer by family history

Lancet

Volumn 361, Issue 9363, 2003, Pages 1101-1102

  Lalloo, Fiona ^a   Varley, Jennifer ^b   Ellis, David ^d   Moran, Anthony ^e   O'Dair, Lindsay ^a   Pharoah, Paul ^f   Evans, D Gareth R ^a   Redmond, E ^a   Shenton, A ^a   Bulman, B ^a   Bulman, M ^a   Howell, A ^b   Thorncroft, M ^b   McGown, G ^b   Seal, S ^c   Stratton, M ^c   Hodgson, S ^d   Mathew, C ^d  

^a ST MARY S HOSPITAL   (United Kingdom)

^b CHRISTIE HOSPITAL   (United Kingdom)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^d GUY S HOSPITAL   (United Kingdom)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

^f University of Manchester ^*

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER DIAGNOSIS; CANCER RISK; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; EARLY CANCER; FAMILY HISTORY; FEMALE; GENE MUTATION; HUMAN; OVARY CARCINOMA; PATHOGENESIS; POPULATION; PREDICTION; PRIORITY JOURNAL;

EID: 0037471838     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(03)12856-5     Document Type: Article

References (5)

1. Ford D., Easton D.F., Stratton M., et al. Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. Am J Hum Genet. 62:1998;676-689.
2. Birch J.M., Hartley A.L., Tricker K.J., et al. Prevalence and diversity of constitutional mutations in the p53 gene among 21 Li-Fraumeni families. Cancer Res. 54:1994;1298-1304.
3. Prevalence and penetrance of BRCA1 and BRCA2 in a population based series of breast cancer cases. Br J Cancer. 83:2000;1301-1308.
4. National Human Genome Research Institute. http://research.nhgri.nih.gov/bic/ (accessed Jan 15, 2003).
5. Easton D.F., Ford D., Bishop D.T. Breast and ovarian cancer incidence in BRCA1-mutation carriers. Am J Hum Genet. 56:1995;265-271.