Solvent-free synthesis of 4-aryl substituted 5-alkoxycarbonyl-6-methyl-3,4-dihydropyridones under microwave irradiation

Tetrahedron Letters

Volumn 44, Issue 18, 2003, Pages 3709-3712

  Rodríguez, Hortensia ^a   Suarez, Margarita ^a   Pérez, Rolando ^a   Petit, Alain ^b   Loupy, André ^b  

^a UNIVERSITY OF HAVANA   (Cuba)

^b UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Dihydropyridones; Microwave irradiation; Solvent free synthesis

Indexed keywords

ACETOACETIC ACID; ACETOACETIC ACID METHYL ESTER; ACID; AMMONIUM ACETATE; BENZALDEHYDE; MELDRUM ACID; PYRIDONE DERIVATIVE; SOLVENT; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHEMICAL REACTION; HEATING; MICROWAVE IRRADIATION; NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; THIN LAYER CHROMATOGRAPHY;

EID: 0037471470     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(03)00625-7     Document Type: Article

References (26)

1. Loupy A., Petit A., Hamelin J., Texier-Boullet F., Jacquault P., Mathé D. Synthesis. 1998;1213-1234.
2. Varma R.S. Green Chem. 1999;43-55.
3. Deshayes S., Liagre M., Loupy A., Luche J.-L., Petit A. Tetrahedron. 55:1999;10870-10951.
4. Rodríguez H., Pérez R., Suárez M., Lam A., Cabrales N., Loupy A. Heterocycles. 55:2001;291-301.
5. Perreux L., Loupy A. Tetrahedron. 57:2001;9199-9223.
6. Arrieta A., Lecea B., Cossio F.P. J. Org. Chem. 63:1998;5869-5874.
7. Lidström P., Tierney J., Wathey B., Westman J. Tetrahedron. 57:2001;9225-9283.
8. Suárez M., Loupy A., Pérez E., Morán L., Gerona G., Morales A., Autié M. Heterocycl. Commun. 2:1996;275-280.
9. Alajarin R., Jordan P., Vaquero J., Alvarez-Builla J. Synthesis. 1995;389-391.
10. Tu S., Wei Q., Ma H., Shi D., Gao Y., Cui G. Synth. Commun. 31:2001;2657-2661.
11. Quiroga J., Cisneros C., Insuasty B., Abonia R., Nogueras M., Sanchez A. Tetrahedron Lett. 42:2001;5625-5627.
12. Stadler A., Kappe C.O. J. Chem. Soc., Perkin Trans. 2. 27:2000;1363-1368.
13. Paul S., Gupta M., Gupta R., Loupy A. Tetrahedron Lett. 42:2001;3827-3829.
14. Suarez M., Loupy A., Salfran E., Moran L., Rolando E. Heterocycles. 51:1999;21-27.
15. Kidwai M., Saxena S., Mohan R., Venkataramanan R. J. Chem. Soc., Perkin Trans. 1. 2002;1845-1846.
16. Bossert F., Vater W. Med. Res. Rev. 9:1989;291-324.
17. Martín-Leon N., Seoane C. Quim. Ind. 36:1990;115-127.
18. Janis R.A., Triggle D.J. J. Med. Chem. 26:1983;775-785.
19. Kuthan J., Kurfurst A. Ind. Eng. Chem. Prod. Res. Dev. 21:1982;191-261.
20. Verdecia Y., Suárez M., Morales A., Rodríguez E., Ochoa E., González L., Martín N., Quinteiro M., Seoane C., Soto J.L. J. Chem. Soc., Perkin Trans. 1. 1996;947-951.
21. Ochoa E., Suárez M., Verdecia Y., Pita B., Martín N., Quinteiro M., Seoane C., Soto J.L., Duque J., Pomes R. Tetrahedron. 54:1998;12409-12420.
22. Rodríguez H., Reyes O., Suárez M., Garay H., Pérez R., Cruz L., Verdecia Y., Martín N., Seaone C. Tetrahedron Lett. 43:2002;439-441.
23. Suárez M., Ochoa E., Pita B., Espinosa R., González L., Martín N., Quinteiro M., Seoane C., Soto J.L. J. Heterocycl. Chem. 34:1997;931-935.
24. 3 (279.72): C, 60.11; H, 5.04; N, 5.01. Found: C, 60.29; H, 5.15; N, 5.19.
25. Morales A., Ochoa E., Suárez M., Verdecia Y., González L., Martín N., Quinteiro M., Seoane C., Soto J.L. J. Heterocycl. Chem. 33:1996;103-107.
26. Svétlik J., Goljer I., Turecek F. J. Chem. Soc., Perkin Trans. 1. 1990;1315-1318.