Intracisternal administration of Angiotensin II AT1 receptor antisense oligodeoxynucleotides protects against cerebral ischemia in spontaneously hypertensive rats

Regulatory Peptides

Volumn 111, Issue 1-3, 2003, Pages 117-122

  Yamakawa, Haruki ^a   Phillips, M Ian ^a,b   Saavedra, Juan M ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b Department of Physiology   (United States)

Author keywords

Brain ischemia; Cerebral blood flow; Genetic hypertension; Renin angiotensin system; Stroke

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANTISENSE OLIGODEOXYNUCLEOTIDE; MESSENGER RNA; OLIGODEOXYNUCLEOTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA POSTREMA; ARTICLE; BLOOD PRESSURE; BLOOD PRESSURE REGULATION; BRAIN EDEMA; BRAIN INFARCTION; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG SPECIFICITY; DRUG TARGETING; ESSENTIAL HYPERTENSION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SOLITARY TRACT NUCLEUS; SYSTEMIC CIRCULATION;

ANGIOTENSIN I; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; AUTORADIOGRAPHY; BLOOD PRESSURE; BRAIN ISCHEMIA; CISTERNA MAGNA; DISEASE MODELS, ANIMAL; HYPERTENSION; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICROINJECTIONS; OLIGONUCLEOTIDES, ANTISENSE; RATS; RATS, INBRED SHR; RECEPTOR, ANGIOTENSIN, TYPE 1; RNA, MESSENGER; TIME FACTORS;

EID: 0037471348     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(02)00264-1     Document Type: Article

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