Structure-based rational design of streptavidin mutants with pseudo-catalytic activity

Journal of Biological Chemistry

Volumn 278, Issue 9, 2003, Pages 7131-7134

  Pazy, Yael ^a   Raboy, Bilha ^a   Matto, Meirav ^a   Bayer, Edward A ^b   Wilchek, Meir ^b   Livnah, Oded ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBODIES; CATALYSIS; ENZYMES; ESTERS; HYDROLYSIS; MUTAGENESIS;

BIOTIN ESTERS;

BIOCHEMISTRY;

ARGININE; AVIDIN; EGG WHITE; LEUCINE; STREPTAVIDIN; POLYMER;

ANIMAL CELL; ARTICLE; BIOTINYLATION; CATALYSIS; CELL MUTANT; DERIVATIZATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENETIC ENGINEERING; HYDROLYSIS; MOLECULAR INTERACTION; NONHUMAN; PHASE TRANSITION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; STRUCTURE ANALYSIS; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; ESCHERICHIA COLI; GENETICS; METABOLISM; MUTATION; PH; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; TIME;

ANIMALIA; BACTERIA (MICROORGANISMS);

ARGININE; AVIDIN; BINDING SITES; CATALYSIS; ESCHERICHIA COLI; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; LEUCINE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; POINT MUTATION; POLYMERS; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; STREPTAVIDIN; TIME FACTORS;

EID: 0037470049     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209983200     Document Type: Article

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