Comparative study of the lubricant performance of Compritol® HD5 ATO and Compritol® 888 ATO: Effect of polyethylene glycol behenate on lubricant capacity

International Journal of Pharmaceutics

Volumn 254, Issue 2, 2003, Pages 263-269

  N'Diaye, A ^a   Jannin, V ^b   Berard V ^a   Andres C ^a   Pourcelot, Y ^a  

^a UNIVERSITÉ DE BOURGOGNE   (France)

^b GATTEFOSSÉ SAS   (France)

Author keywords

Compritol ; Glyceryl dibehenate; Lubricant capacity; Polyethylene glycol; Powder compression

Indexed keywords

BEHENIC ACID; COMPRITOL HD5 ATO; EXCIPIENT; GLYCEROL BEHENATE; LUBRICATING AGENT; POLYETHYLENE GLYCOL DIBEHENATE; UNCLASSIFIED DRUG;

ARTICLE; DISSOLUTION; LUBRICATION; NEBULIZATION; PRIORITY JOURNAL;

EID: 0037467166     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(03)00027-9     Document Type: Article

References (7)

1. Abramovici B., Gromenil J.C., Molard F., Blanc F. Etude comparative des propriétés lubrifiantes d'un nouvel excipient le tribéhénate de glycérol (Compritol 888) par rapport au stéarate de magnésium. S.T.P. Pharma. 2:1986;403-409.
2. Doelker, E., 1994. Assessment of powder compaction. In: Chulia, D., Deleuil, M., Pourcelot, Y., (Eds.), Powder Technology and Pharmaceutical Processes. Elsevier, Amsterdam, pp. 403-460.
3. Fell J.T., Newton J.M. Determination of tablet strength by the diametral-compression test. J. Pharm. Sci. 59:1970;688-691.
4. Jarosz P.J., Parrott E.L. Effect of lubricant on tensile strengths of tablets. Drug Dev. Ind. Pharm. 10:1984;2059-2073.
5. Miller T.A., York P. Pharmaceutical tablet lubrification. Int. J. Pharm. 41:1988;1-19.
6. Miralles M.J., McGinity J.W., Martin A. Combinated water-soluble carriers for coprecipitates of tolbutamide. J. Pharm. Sci. 71:1982;302-304.
7. Zanorwick, P., 1994. Lubrification in solid dosage form design and manufacture. In: Swarbrik, J., Boylan, J.C. (Eds.), Encyclopedia of Pharmaceutical Technology, vol. 9. Marcel Dekker, New York, pp. 87-112.