High resolution crystal structures of human Rab5a and five mutants with substitutions in the catalytically important phosphate-binding loop

Journal of Biological Chemistry

Volumn 278, Issue 4, 2003, Pages 2452-2460

  Zhu, Guangyu ^a   Liu, Jian ^b   Terzyan, Simon ^a   Zhai, Peng ^a   Li, Guangpu ^b   Zhang, Xuejun C ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; HYDROLYSIS; PROTEINS;

MUTATIONS;

MUTAGENS;

ALUMINUM FLUORIDE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; GUANOSINE TRIPHOSPHATE; MUTANT PROTEIN; RAB PROTEIN; RAB5A PROTEIN; UNCLASSIFIED DRUG; DNA; PHOSPHATE; PROLINE; RECOMBINANT PROTEIN;

ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; ESCHERICHIA COLI; GENE MUTATION; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; GENETICS; HUMAN; METABOLISM; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI;

CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DNA; ESCHERICHIA COLI; GUANOSINE TRIPHOSPHATE; HUMANS; HYDROLYSIS; MODELS, MOLECULAR; MUTATION; NUCLEIC ACID CONFORMATION; PHOSPHATES; PROLINE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RAB5 GTP-BINDING PROTEINS; RECOMBINANT PROTEINS;

EID: 0037462808     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211042200     Document Type: Article

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