The cytokine-inducible Scr homology domain-containing protein negatively regulates signaling by promoting apoptosis in erythroid progenitor cells

Journal of Biological Chemistry

Volumn 278, Issue 4, 2003, Pages 2654-2660

  Ketteler, Robin ^a   Moghraby, Chetal S ^a   Hsiao, Jonathan G ^a,b   Sandra, Olivier ^a   Lodish, Harvey F ^b,c   Klingmüller, Ursula ^a  

^a MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CELLS; CYTOLOGY; MUTAGENESIS;

COLONY ASSAYS;

PROTEINS;

COMPLEMENTARY DNA; CYTOKINE; CYTOKINE INDUCIBLE SH2 DOMAIN CONTAINING PROTEIN; ERYTHROPOIETIN RECEPTOR; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; UNCLASSIFIED DRUG; CYTOKINE INDUCIBLE SH2 CONTAINING PROTEIN; CYTOKINE INDUCIBLE SH2-CONTAINING PROTEIN; DNA BINDING PROTEIN; IMMEDIATE EARLY PROTEIN; MILK PROTEIN; PHOTOPROTEIN; STAT5 PROTEIN; TRANSACTIVATOR PROTEIN; TYROSINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; ERYTHROID CELL; FETUS LIVER; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC TRANSDUCTION; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; SIGNAL TRANSDUCTION; STEM CELL; ANIMAL; CELL DIVISION; CELL SEPARATION; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; ERYTHROCYTE; FLOW CYTOMETRY; GENE DELETION; GENETICS; IMMUNOBLOTTING; LIVER; METABOLISM; MUTATION; PHOSPHORYLATION; PRENATAL DEVELOPMENT; SERODIAGNOSIS;

ANIMALIA; UNIDENTIFIED RETROVIRUS;

ANIMALS; APOPTOSIS; CELL DIVISION; CELL SEPARATION; CELL SURVIVAL; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; FLOW CYTOMETRY; GENE DELETION; GREEN FLUORESCENT PROTEINS; IMMEDIATE-EARLY PROTEINS; IMMUNOBLOTTING; LIVER; LUMINESCENT PROTEINS; MICE; MILK PROTEINS; MUTATION; PHOSPHORYLATION; PRECIPITIN TESTS; RECOMBINANT FUSION PROTEINS; RETROVIRIDAE; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; STEM CELLS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANS-ACTIVATORS; TYROSINE;

EID: 0037462735     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211236200     Document Type: Article

References (32)

1. Metcalf, D. (1989) Nature 339, 27-30
2. Wu, H., Liu, X., Jaenisch, R., and Lodish, H. F. (1995) Cell 83, 59-67
3. Klingmüller, U. (1997) Eur. J. Biochem. 249, 637-647
4. Huang, L. J., Constantinescu, S. N., and Lodish, H. F. (2001) Mol. Cell 8, 1327-1338
5. Klingmüller, U., Bergelson, S., Hsiao, J. G., and Lodish, H. F. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8324-8328
6. Damen, J. E., Wakao, H., Miyajima, A., Krosl, J., Humphries, R. K., Cutler, R. L., and Krystal, G. (1995) EMBO J. 14, 5557-5568
7. Gobert, S., Chretien, S., Gouilleux, F., Muller, O., Pallard, C., Dusanter-Fourt, I., Groner, B., Lacombe, C., Gisselbrecht, S., and Mayeux, P. (1996) EMBO J. 15, 2434-2441
8. Klingmüller, U., Wu, H., Hsiao, J. G., Toker, A., Duckworth, B. C., Cantley, L. C., and Lodish, H. F. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 3016-3021
9. Klingmüller, U., Lorenz, U., Cantley, L. C., Neel, B. G., and Lodish, H. F. (1995) Cell 80, 729-738
10. Tauchi, T., Damen, J. E., Toyama, K., Feng, G. S., Broxmeyer, H. E., and Krystal, G. (1996) Blood 87, 4495-44501
11. Silva, M., Benito, A., Sanz, C., Prosper, F., Ekhterae, D., Nunez, G., and Fernandez-Luna, J. (1999) J. Biol. Chem. 274, 22165-22169
12. Socolovsky, M., Fallon, A. E., Wang, S., Brugnara, C., and Lodish, H. F. (1999) Cell 98, 181-191
13. Motoyama, N., Kimura, T., Takahashi, T., Watanabe, T., and Nakano, T. (1999) J. Exp. Med. 189, 1691-1698
14. Socolovsky, M., Nam, H., Fleming, M. D., Haase, V. H., Brugnara, C., and Lodish, H. F. (2001) Blood 98, 3261-3273
15. Yoshimura, A., Ohkubo, T., Kiguchi, T., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Hara, T., and Miyajima, A. (1995) EMBO J. 14, 2816-2826
16. Verdier, F., Chretien, S., Muller, O., Varlet, P., Yoshimura, A., Gisselbrecht, S., Lacombe, C., and Mayeux, P. (1998) J. Biol. Chem. 273, 28185-28190
17. Eyckerman, S., Verhee, A., Van der Heyden, J., Lemmens, I., Van Ostade, X., Vandekerckhove, J., and Tavernier, J. (2001) Nat. Cell Biol. 3, 1114-1119
18. Sasaki, A., Yasukawa, H., Shouda, T., Kitamura, T., Dikic, I., and Yoshimura, A. (2000) J. Biol. Chem. 275, 29338-29347
19. Hortner, M., Nielsch, U., Mayr, L. M., Heinrich, P. C., and Haan, S. (2002) Eur. J. Biochem. 269, 2516-2526
20. Matsumoto, A., Masuhara, M., Mitsui, K., Yokouchi, M., Ohtsubo, M., Misawa, H., Miyajima, A., and Yoshimura, A. (1997) Blood 89, 3148-3154
21. Jegalian, A. G., and Wu, H. (2002) J. Interferon Cytokine Res. 22, 853-860
22. Matsumoto, A., Seki, Y., Kubo, M., Ohtsuka, S., Suzuki, A., Hayashi, I., Tsuji, K., Nakahata, T., Okabe, M., Yamada, S., and Yoshimura, A. (1999) Mol. Cell. Biol. 19, 6396-6407
23. Li, S., Chen, S., Xu, X., Sundstedt, A., Paulsson, K. M., Anderson, P., Karlsson, S., Sjörgren, H. O., and Wang, P. (2000) J. Exp. Med. 191, 985-994
24. Marine, J. C., McKay, C., Wang, D., Topham, D. J., Parganas, E., Nakajima, H., Pendeville, H., Yasukawa, H., Sasaki, A., Yoshimura, A., and Ihle, J. N. (1999) Cell 98, 617-627
25. Ketteler, R., Glaser, S., Sandra, O., Martens, U. M., and Klingmuller, U. (2002) Gene Ther. 9, 477-487
26. Ketteler, R., Heinrich, A., Offe, J., Becker, V., Cohen, J., Neumann, D., and Klingmüller, U. (2002) J. Biol. Chem. 277, 26547-26552
27. Kina, T., Ikuta, K., Takayama, E., Wada, K., Majumdar, A. S., Weissman, I. L., and Katsura, Y. (2000) Brit. J. Haematol. 109, 280-287
28. Endo, T. A., Masuhara, M., Yokouchi, M., Suzuki, R., Sakamoto, H., Mitsui, K., Matsumoto, A., Tanimura, S., Ohtsubo, M., Misawa, H., Miyazaki, T., Leonor, N., Taniguchi, T., Fujita, T., Kanakura, Y., Komiya, S., and Yoshimura, A. (1997) Nature 387, 921-924
29. Nosaka, T., Kawashima, T., Misawa, K., Ikuta, K., Mui, A., and Kitamura, T. (1999) EMBO J. 18, 4754-4765
30. Bittorf, T., Buchse, T., Sasse, T., Jaster, R., and Brock, J. (2001) Cell. Signalling 13, 673-681
31. Gregory, T., Yu, C., Ma, A., Orkin, S. H., Blobel, G. A., and Weiss, M. J. (1999) Blood 94, 87-96
32. Kapur, R., and Zhang, L. (2001) J. Biol. Chem. 276, 1099-1106