Schizosaccharomyces pombe Int6 and Ras homologs regulate cell division and mitotic fidelity via the proteasome

Cell

Volumn 112, Issue 2, 2003, Pages 207-217

  Yen, Hsueh Chi S ^a   Gordon, Colin ^b   Chang, Eric C ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CYCLINE; PROTEIN; PROTEIN INT6; PROTEIN RPN5; RAS PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL DIVISION; CHROMOSOME SEGREGATION; CONTROLLED STUDY; GENE OVEREXPRESSION; MITOSIS; NONHUMAN; PRIORITY JOURNAL; SCHIZOSACCHAROMYCES POMBE; YEAST;

FUNGI; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE;

EID: 0037462417     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(03)00043-6     Document Type: Article

References (66)

1. Adams J. Proteasome inhibition. a novel approach to cancer therapy Trend. Mol. Med. 8:2002;49-54.
2. Akiyoshi Y., Clayton J., Phan L., Yamamoto M., Hinnebusch A.G., Watanabe Y., Asano K. Fission yeast homolog of murine Int-6 protein, encoded by mouse mammary tumor virus integration site, is associated with the conserved core subunits of eukaryotic translation initiation factor 3. J. Biol. Chem. 276:2001;10056-10062.
3. Amsterdam A., Pitzer F., Baumeister W. Changes in intracellular localization of proteasomes in immortalized ovarian granulosa cells during mitosis associated with a role in cell cycle control. Proc. Natl. Acad. Sci. USA. 90:1993;99-103.
4. Asano K., Merrick W.C., Hershey J.W. The translational initiation factor eIF3-p48 subunit is encoded by int6, a site of frequent integration by the mouse mammary tumor virus genome. J. Biol. Chem. 272:1997;23477-23480.
5. Artavanis-Tsakonas S., Rand M.D., Lake R.J. Notch signaling. cell fate control and signal integration in development Science. 284:1999;770-776.
6. Ayscough K., Warren G. Inhibition of protein synthesis disrupts the Golgi apparatus in the fission yeast, Schizosaccharomyces pombe. Yeast. 10:1994;1-11.
7. Balasubramanian M.K., Helfman D.M., Hemmingsen S.M. A new tropomyosin essential for cytokinesis in the fission yeast S. pombe. Nature. 360:1992;84-87.
8. Bandyopadhyay A., Matsumoto T., Maitra U. Fission yeast Int6 is not essential for global translation initiation, but deletion of int6+ causes hypersensitivity to caffeine and affects spore formation. Mol. Biol. Cell. 11:2000;4005-4018.
9. Baselga J., Norton L. Focus on breast cancer. Cancer Cell. 1:2000;319-322.
10. Berry L.D., Feoktistova A., Wright M.D., Gould K.L. The Schizosaccharomyces pombe dim1(+) gene interacts with the anaphase-promoting complex or cyclosome (APC/C) component lid1(+) and is required for APC/C function. Mol. Cell. Biol. 19:1999;2535-2546.
11. Chang E.C., Barr M., Wang Y., Jung V., Xu H., Wigler H.M. Cooperative interaction of S. pombe proteins required for mating and morphogenesis. Cell. 79:1994;131-141.
12. Chen C.-R., Li Y.-C., Chen J., Hou M.C., Papadaki P., Chang E.C. Moe1, a novel conserved protein in Schizosaccharomyces pombe, interacts with a ras effector, Scd1, to affect proper spindle formation. Proc. Natl. Acad. Sci. USA. 96:1999;517-522.
13. Chen C.-R., Chen J., Chang E.C. A conserved interaction between Moe1 and Mal3 is important for proper spindle formation in Schizosaccharomyces pombe. Mol. Biol. Cell. 11:2000;4067-4077.
14. Criekinge W.V., Beyaert R. Yeast two-hybrid. state of the art Biol. Proc. Online. 2:1999;1-28.
15. Desbois C., Rousset R., Bantignies F., Jalinot P. Exclusion of Int-6 from PML nuclear bodies by binding to the HTLV-I Tax oncoprotein. Science. 273:1996;951-953.
16. Ferrell K., Wilkinson C.R., Dubiel W., Gordon C. Regulatory subunit interactions of the 26S proteasome, a complex problem. Trends Biochem. Sci. 25:2000;83-88.
17. -. Mol. Gen. Genet. 215:1988;26-31.
18. Fukui Y., Kozasa T., Kaziro Y., Takeda T., Yamamoto M. Role of a ras homolog in the life cycle of Schizosaccharomyces pombe. Cell. 44:1986;329-336.
19. Gachet Y., Tournier S., Millar J.B., Hyams J.S. A MAP kinase-dependent actin checkpoint ensures proper spindle orientation in fission yeast. Nature. 412:2001;352-355.
20. Glickman M.H., Rubin D.M., Fried V.A., Finley D. The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol. Cell. Biol. 18:1998;3146-3162.
21. Gohring U.J., Schondorf T., Kiecker V.R., Becker M., Kurbacher C., Scharl A. Immunohistochemical detection of H-ras protooncoprotein p21 indicates favorable prognosis in node-negative breast cancer patients. Tumour Biol. 20:1999;173-183.
22. Gordon C., McGurk G., Dillon P., Rosen C., Hastie N.D. Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit. Nature. 366:1993;355-357.
23. Grishchuk E.L., Howe J.L., McIntosh J.R. A screen for genes involved in the anaphase proteolytic pathway identifies tsm1(+), a novel Schizosaccharomyces pombe gene important for microtubule integrity. Genetics. 149:1998;1251-1264.
24. Guo J., Sen G. Characterization of the interaction between the interferon-induced protein P56 and the Int6 protein encoded by the locus of insertion of the mouse mammary tumor virus. J. Virol. 74:2000;1892-1899.
25. Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell. 100:2000;57-70.
26. Hemelaar J., Bex F., Booth B., Cerundolo V., McMichael A., Daenke S. Human T-cell leukemia virus type 1 Tax protein binds to assembled nuclear proteasomes and enhances their proteolytic activity. J. Virol. 75:2001;11106-11115.
27. Hoareau Alves K., Bochard V., Rety S., Jalinot P. Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome. FEBS Lett. 527:2002;15-21.
28. Hofmann K., Bucher P. The PCI domain. a common theme in three multiprotein complexes Trends Biochem. Sci. 23:1998;204-205.
29. Kiaris H., Spandidos D.A. Mutations of ras genes in human tumours. Int. J. Oncol. 7:1995;413-421.
30. Kim T., Hofmann K., von Arnim A.G., Chamovitz D.A. PCI complexes. pretty complex interactions in diverse signaling pathways Trends Plant Sci. 6:2001;379-386.
31. Lafarga M., Fernandez R., Mayo I., Berciano M.T., Castano J.G. Proteasome dynamics during cell cycle in rat Schwann cells. Glia. 38:2002;313-328.
32. Laney J.D., Hochstrasser M. Substrate targeting in the ubiquitin system. Cell. 97:1999;427-430.
33. Leclercq G. Molecular forms of the estrogen receptor in breast cancer. J. Steroid Biochem. Mol. Biol. 80:2002;259-272.
34. Lehmann A., Janek K., Braun B., Kloetzel P.M., Enenkel C. 20 S proteasomes are imported as precursor complexes into the nucleus of yeast. J. Mol. Biol. 317:2002;401-413.
35. Lengauer C., Kinzler K.W., Vogelstein B. Genetic instabilities in human cancers. Nature. 396:1998;643-649.
36. Liu S., Liu W., Jakubczak J.L., Erexson G.L., Tindall K.R., Chan R., Muller W.J., Adhya S., Garges S., Merlino G. Genetic instability favoring transversions associated with ErbB2-induced mammary tumorigenesis. Proc. Natl. Acad. Sci. USA. 99:2002;3770-3775.
37. Lonning P.E. The role of aromatase inactivators in the treatment of breast cancer. Int. J. Clin. Oncol. 7:2002;265-270.
38. Luca F.C., Ruderman J.V. Control of programmed cyclin destruction in a cell-free system. J. Cell Biol. 109:1989;1895-1909.
39. Marchetti A., Buttitta F., Miyazaki S., Gallahan D., Smith G., Callahan R. Int-6, a highly conserved, widely expressed gene, is mutated by mouse mammary tumor virus in mammary preneoplasia. J. Virol. 69:1995;1932-1938.
40. Marchetti A., Buttitta F., Pellegrini S., Bertacca G., Callahan R. Reduced expression of INT-6/eIF3-p48 in human tumors. Int. J. Oncol. 18:2001;175-179.
41. Miyazaki S., Imatani A., Ballard L., Marchetti A., Buttitta F., Albertsen H., Nevanlinna H.A., Gallahan D., Callahan R. The chromosome location of the human homolog of the mouse mammary tumor-associated gene INT6 and its status in human breast carcinomas. Genomics. 46:1997;155-158.
42. Nadin-Davis S.A., Nasim A., Beach D. Involvement of ras in sexual differentiation but not in growth control in fission yeast. EMBO J. 5:1986;2963-2971.
43. Pajonk F., McBride W.H. The proteasome in cancer biology and treatment. Radiat. Res. 156:2001;447-459.
44. Palmer A., Mason G.G., Paramio J.M., Knecht E., Rivett A.J. Changes in proteasome localization during the cell cycle. Eur. J. Cell Biol. 64:1994;163-175.
45. Rasmussen S.B., Kordon E., Callahan R., Smith G.H. Evidence for the transforming activity of a truncated Int6 gene, in vitro. Oncogene. 20:2001;5291-5301.
46. Reits E.A., Benham A.M., Plougastel B., Neefjes J., Trowsdale J. Dynamics of proteasome distribution in living cells. EMBO J. 16:1997;6087-6094.
47. Rodenhuis M. ras and human tumors. Semin. Cancer Biol. 3:1992;241-247.
48. Sáez C., Japon M.A., Ramos-Morales F., Romero F., Segura D.I., Tortolero M., Pintor-Toro J.A. hpttg is over-expressed in pituitary adenomas and other primary epithelial neoplasias. Oncogene. 18:1999;5473-5476.
49. Saito A., Watanabe T.K., Shimada Y., Fujiwara T., Slaughter C.A., DeMartino G.N., Tanahashi N., Tanaka K. cDNA cloning and functional analysis of p44.5 and p55, two regulatory subunits of the 26S proteasome. Gene. 203:1997;241-250.
50. Schondorf T., Andrack A., Niederacher D., Scharl A., Becker M., Engel H., Gohring U.J. H-ras gene amplification or mutation is not common in human primary breast cancer. Oncol. Rep. 6:1999;1029-1033.
51. Schwechheimer C., Deng X.W. COP9 signalosome revisited. a novel mediator of protein degradation Trends Cell Biol. 11:2001;420-426.
52. Sears R., Leone G., DeGregori J., Nevins J.R. Ras enhances Myc protein stability. Mol. Cell. 3:1999;169-179.
53. Tatebe H., Yanagida M. Cut8, essential for anaphase, controls localization of 26S proteasome, facilitating destruction of cyclin and cut2. Curr. Biol. 10:2000;1329-1338.
54. Tekmal R.R., Keshava N. Role of MMTV integration locus cellular genes in breast cancer. Front. Biosci. 2:1997;519-526.
55. van't Veer L.J., Dai H., van de Vijver M.J., He Y.D., Hart A.A., Mao M., Peterse H.L., van der Kooy K., Marton M.J., Witteveen A.T., Schreiber G.J. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 415:2002;530-536.
56. Venkitaraman A.R. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell. 108:2002;171-182.
57. Verma R., Chen S., Feldman R., Schieltz D., Yates J., Dohmen J., Deshaies R.J. Proteasomal proteomics. identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes Mol. Biol. Cell. 11:2000;3425-3439.
58. Wilkinson C.R., Wallace M., Seeger M., Dubiel W., Gordon C. Mts4, a non-ATPase subunit of the 26 S protease in fission yeast, is essential for mitosis and interacts directly with the ATPase subunit Mts2. J. Biol. Chem. 272:1997;25768-25777.
59. Wilkinson C.R., Wallace M., Morphew M., Perry P., Allshire R., Javerzat J.P., McIntosh J.R., Gordon C. Localization of the 26S proteasome during mitosis and meiosis in fission yeast. EMBO J. 17:1998;6465-6476.
60. Wilkinson C.R., Ferrell K., Penney M., Wallace M., Dubiel W., Gordon C. Analysis of a gene encoding Rpn10 of the fission yeast proteasome reveals that the polyubiquitin-binding site of this subunit is essential when Rpn12/Mts3 activity is compromised. J. Biol. Chem. 275:2000;15182-15192.
61. Wiseman B.S., Werb Z. Stromal effects on mammary gland development and breast cancer. Science. 296:2002;1046-1049.
62. Wood V., Gwilliam R., Rajandream M.A., Lyne M., Lyne R., Stewart A., Sgouros J., Peat N., Hayles J., Baker S.et al. The genome sequence of Schizosaccharomyces pombe. Nature. 415:2002;871-880.
63. Yahalom A., Kim T.H., Winter E., Karniol B., von Arnim A.G., Chamovitz D.A. Arabidopsis eIF3e (INT-6) associates with both eIF3c and the COP9 signalosome subunit CSN7. J. Biol. Chem. 276:2001;334-340.
64. Yen H.-C.S., Chang E.C. Yin6, a fission yeast Int6 homolog, complexes with Moe1 and plays a role in chromosome segregation. Proc. Natl. Acad. Sci. USA. 97:2000;14370-14375.
65. Zhang X., Horwitz G.A., Prezant T.R., Valentini A., Nakashima M., Bronstein M.D., Melmed S. Structure, expression and function of human pituitary tumor-transforming gene (PTTG). Mol. Endocrinol. 13:1999;156-166.
66. Zou H., McGarry T.J., Bernal T., Kirschner M.W. Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis. Science. 285:1999;418-422.