Structural and functional determinants of human plasma phospholipid transfer protein activity as revealed by site-directed mutagenesis of charged amino acids

Biochemistry

Volumn 42, Issue 15, 2003, Pages 4444-4451

  Ponsin, Gabriel ^a,b   Qu, Shi Jing ^a   Fan, Hui Zhen ^a,c   Pownall, Henry J ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITÉ DE LYON   (France)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; MOLECULES; MUTAGENESIS; PHOSPHOLIPIDS; PROTEINS; SOLVENTS; SUBSTITUTION REACTIONS;

TRANSFER ACTIVITY;

BIOCHEMISTRY;

AMINO ACID; BACTERICIDAL PERMEABILITY INCREASING PROTEIN; MUTANT PROTEIN; PHOSPHOLIPID TRANSFER PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL STRAIN COS7; CHEMICAL STRUCTURE; CONTROLLED STUDY; DATA ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE STRUCTURE; HYDROPHOBICITY; MOLECULE; MULTIGENE FAMILY; NONHUMAN; PHOSPHOLIPID TRANSFER; PLASMA; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; SURFACE CHARGE; WILD TYPE;

AMINO ACIDS, ACIDIC; AMINO ACIDS, BASIC; ANIMALS; CARRIER PROTEINS; COS CELLS; HUMANS; LIPOPROTEINS, HDL; MEMBRANE PROTEINS; MUTAGENESIS, SITE-DIRECTED; PHOSPHOLIPID TRANSFER PROTEINS; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 0037461269     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi027006g     Document Type: Article

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