Ergothioneine inhibits oxidative stress- and TNF-α-induced NF-κ B activation and interleukin-8 release in alveolar epithelial cells

Biochemical and Biophysical Research Communications

Volumn 302, Issue 4, 2003, Pages 860-864

  Rahman, Irfan ^a   Gilmour, Peter S ^a   Jimenez, Luis A ^a   Biswas, Saibal K ^a   Antonicelli, Frank ^b   Aruoma, Okezie I ^c  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^c CHARING CROSS HOSPITAL   (United Kingdom)

Author keywords

A549 cells; Dietary antioxidants; Ergothioneine; Glutathione; IL 8; NF B; Oxidant

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; THIONEINE; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; ENZYME ASSAY; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; OXIDATIVE STRESS; PRIORITY JOURNAL; TRANSCRIPTION INITIATION;

FELIS CATUS;

EID: 0037459190     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00224-9     Document Type: Article

References (28)

1. Brenman F.M., Maini R.N., Feldmann M. Cytokine expression in chronic inflammatory disease. Br. Med. Bull. 51:1995;368-384.
2. Rahman I., MacNee W. Oxidative stress and regulation of glutathione synthesis in lung inflammation. Eur. Respir. J. 16:2000;534-554.
3. Rahman I., MacNee W. Role of transcription factors in inflammatory lung diseases. Thorax. 55:1998;601-612.
4. Rahman I. Oxidative stress transcription factors and chromatin remodeling in lung inflammation. Biochem. Pharmacol. 60:2000;1041-1049.
5. Rahman I., Gilmour P., Jimenez L.A., MacNee W. Oxidative stress and TNF-α induce histone acetylation and AP-1/NF-κB in alveolar epithelial cells: potential mechanism in inflammatory gene transcription. Mol. Cell Biochem. 234/235:2002;239-248.
6. Moncaster J.A., Walsh D.T., Gentleman S.M., Jen L.-S., Aruoma O.I. Ergothioneine treatment protects neurons against N-methyl-D-aspartate excitotoxicity in an in vivo rat retinal model. Neurosci. Lett. 328:2002;55-59.
7. Melville D.B., Ergothioneine Vitamin Horm. XVII:1959;155-204.
8. Aruoma O.I., Whiteman M.E., Halliwell B. Antioxidant action of ergothioneine: assessment of its ability to scavenge peroxynitrite. Biochem. Biophys. Res. Commun. 231:1997;389-391.
9. Aruoma O.I., Spencer J.P.E., Mahmood N. Protection against oxidative damage and cell death by the natural antioxidant ergothioneine. Food Chem. Toxicol. 37:1999;1043-1053.
10. 10 -induced transcription of interleukin-8 Am. J. Physiol: Lung Cell Mol. Physiol. 281:2001;L598-L606.
11. Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidised glutathione: applications to mammalian blood and other tissue. Anal. Biochem. 27:1969;502-522.
12. Rahman I., Li X.Y., Donaldson K., Harrison D.J., MacNee W. Glutathione homeostasis in alveolar epithelial cells in vitro and lung in vivo under oxidative stress. Am. J. Physiol. (Lung Cell. Mol. Physiol.). 269:1995;L285-L292.
13. Rahman I., MacNee W. Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. Free Radical Biol. Med. 28:2000;1405-1420.
14. 2 and tumor necrosis factor-α in endothelial and epithelial cells J. Biol. Chem. 272:1997;32910-32918.
15. Rahman I., Antonicelli F., MacNee W. Molecular mechanism of the regulation of gluthatione synthesis by tumor necrosis factor-α and dexamethasone in human alveolar epithelial cells. J. Biol. Chem. 274:1999;5088-5096.
16. Deforge L.E., Preston A., Takeuchi E., Kenney J., Boxer L.A., Remick D.G. Regulation of interleukin-8 gene expression by oxidant stress. J. Biol. Chem. 268:1993;25568-25576.
17. Strieter R.M. Interleukin-8: a very important chemokine of the human epithelium. Am. J. Physiol. Lung Cell Mol. Physiol. 283:2002;L688-L689.
18. Roebuck K.A. Oxidant stress regulation of IL-8 and ICAM-gene expression: differential activation and binding of the transcription factors AP-1 and NF-κB. Int. J. Mol. Med. 4:1999;223-230.
19. Pei X.Y., Nakanishi Y., Inoue H., Takayama K., Bai F., Kara H. Polycyclic aromatic hydrocarbons induce IL-8 expression through nuclear factor κB activation in A549 cell line. Cytokine. 19:2002;236-241.
20. Park G.Y., Le S., Park K.H., Le C.T., Kim Y.W., Han S.K., Shim Y.S., Yoo C.G. Anti-inflammatory effect of adenovirus-mediated IκBα overexpression in respiratory epithelial cells. Eur. Respir. J. 18:2001;801-809.
21. Antonicelli F., Parmentier M., Drost E.M., Hirani N., Rahman I., Donaldson K., MacNee W. N Acystelyn inhibits oxidant-mediated interleukin-8 expression and NF-κB nuclear binding in alveolar epithelial cells. Free Radical Biol. Med. 32:2002;492-502.
22. Jimenez L.A., Drost E.M., Gilmour P.S., Rahman I., Antonicelli F., Ritchie H., MacNee W., Donaldson K. PM(10)-exposed macrophages stimulate a proinflammatory response in lung epithelial cells via TNF-α Am. J. Physiol. Lung Cell Mol. Physiol. 282:2002;L237-L248.
23. Matsusaka T., Fujikawa K., Nishio Y., Mukaida N., Matsushima K., Kishimoto T., Akira S. Transcription factors NF-IL6 and NF-κB synergistically activate transcription of the inflammatory cytokines, interleukin-6 and interleukin-8. Proc. Natl. Acad. Sci. USA. 90:1993;10193-10197.
24. Kunsch C., Lang R.K., Rosen C.A., Shannon M.F. Synergistic transcriptional activation of the IL-8 gene by NF-κB p65 (RelA) and NF-IL-6. J. Immunol. 153:1994;153-164.
25. A.R. Brasier, M. Jamaluddin, A. Casola, W. Duan, Q. Shen, R.P. Garofalo, A promoter recruitment mechanism for tumour necrosis factor-α-induced interleukin-8 transcription in type II pulmonary epithelial cells. Dependence on nuclear abundance of Rel, NF-κB1, and c-Rel transcription factors. J. Biol. Chem. 273 (1998) 3551-3561.
26. Mastronarde J.G., Monick M.M., Mukaida N., Matsushima K., Hunninghake G.W. Activator protein-1 is the preferred transcription factor for cooperative interaction with nuclear factor-κB in respiratory syncytial virus-induced interleukin-8 gene expression in airway epithelium. J. Infect. Dis. 5:1998;1275-1281.
27. Aruoma O.I., Halliwell B., Hoey B.M., Butler J. The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Rad. Biol. Med. 6:1989;593-597.
28. Matsumoto K., Hashimoto S., Gon Y., Nakayama T., Takizawa H., Horie T. N-Acetylcysteine inhibits IL-. 1α -induced IL-8 secretion by bronchial epithelial cells Respir. Med. 92:1998;512-515.