Absence of multiple local minima effects in intensity modulated optimization with dose-volume constraints

Physics in Medicine and Biology

Volumn 48, Issue 2, 2003, Pages 183-210

  Llacer, Jorge ^a   Deasy, Jospeh O ^b   Bortfeld, Thomas R ^c   Solberg, Timothy D ^d   Promberger, Claus ^e  

^a LLC 130 ^*  (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e BRAINLAB AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CONSTRAINT THEORY; DOSIMETRY; OPTIMIZATION; PROBLEM SOLVING; STATISTICAL METHODS;

INTENSITY MODULATION;

RADIOTHERAPY;

ALGORITHM; ANALYTICAL ERROR; ARTICLE; CANCER RADIOTHERAPY; CONTROLLED STUDY; HEAD AND NECK CARCINOMA; HISTOGRAM; HUMAN; MATHEMATICAL MODEL; MENINGIOMA; METHODOLOGY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROSTATE CANCER; RADIATION BEAM; RADIATION DOSE DISTRIBUTION; RADIOLOGICAL PARAMETERS; RANDOMIZATION; SIMULATION; SPINE TUMOR; SPLEEN TUMOR; STATISTICAL ANALYSIS; TREATMENT PLANNING;

ALGORITHMS; CARCINOMA, SQUAMOUS CELL; DOSE-RESPONSE RELATIONSHIP, RADIATION; HEAD AND NECK NEOPLASMS; HUMANS; MALE; NEOPLASMS; PHANTOMS, IMAGING; PROSTATIC NEOPLASMS; RADIOMETRY; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, CONFORMAL; REPRODUCIBILITY OF RESULTS; SCATTERING, RADIATION; SENSITIVITY AND SPECIFICITY; SPINAL NEOPLASMS; SPLENIC NEOPLASMS;

EID: 0037458222     PISSN: 00319155     EISSN: None     Source Type: Journal    
DOI: 10.1088/0031-9155/48/2/304     Document Type: Article

References (11)

1. Alber M et al 2002 On the degeneracy of the IMRT optimization problem Med. Phys. 29 2584-89
2. Bortfeld T et al 1990 Methods of image reconstruction from projections applied to conformation radiotherapy Phys. Med. Biol. 35 1423-34
3. Bortfeld T 1995 Dosiskonformation in der Tumortherapie mit externer ionisierender Strahlung: Physikalische Möglichkeiten und Grenzen (Dose conformation in radiotherapy with external ionizing radiation: physical possibilities and limitations) PhD Thesis University of Heidelberg
4. Bortfeld T 1997 Clinically relevant intensity modulation optimization using physical criteria Proc. 12th Int. Conf. on the Use of Computers in Radiation Therapy (Salt Lake City, UT) ed D D Leavitt and G Starkschall (Madison, WI: Medical Physics Publishing) pp 1-4
5. Deasy J O 1997 Multiple local minima in radiotherapy optimization problems with dose-volume constraints Med. Phys. 24 1157-61
6. Llacer J et al 2001 Comparative behavior of the dynamically penalized likelihood algorithm in inverse radiation therapy planning Phys. Med. Biol. 46 2637-63
7. Rowbottom C G and Webb S 2002 Configuration space analysis of common cost functions in radiotherapy beam-weight optimization algorithms Phys. Med. Biol. 47 65-77
8. Shepard D M, Olivera G, Angelos L, Sauer O, Reckwerdt P and Mackie T R 1999 A simple model for examining issues in radiotherapy optimization Med. Phys. 26 1212-21
9. Webb S 1995 Optimizing radiation therapy inverse treatment planning using the simulated annealing technique Int. J. Imaging Syst. Technol. 6 71-9
10. Solla S A et al 1986 Configuration space analysis for optimization problems Desired Systems and Biological Organization ed E Bienenstock (New York: Springer) ch 40, pp 283-93
11. Wu Q and Mohan R 2002 Multiple local minima in IMRT optimization based on dose-volume criteria Med. Phys. 29 1514-27