Age-dependent impairment of reendothelialization after arterial injury: Role of vascular endothelial growth factor

Circulation

Volumn 107, Issue 2, 2003, Pages 230-233

  Gennaro, Giuseppa ^a   Ménard, Catherine ^a   Michaud, Sophie Élise ^a   Rivard, Alain ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Aging; Atherosclerosis; Endothelium; Growth substances

Indexed keywords

VASCULOTROPIN;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTERY INJURY; ARTERY INTIMA PROLIFERATION; ARTICLE; ATHEROSCLEROSIS; CELL GROWTH; CONTROLLED STUDY; EPITHELIZATION; GENE TRANSFER; GROWTH REGULATION; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ADENOVIRIDAE; AGE FACTORS; AGING; ANGIOPLASTY, BALLOON; ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; GENETIC VECTORS; HYPERPLASIA; ILIAC ARTERY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOKINES; MUSCLE, SMOOTH, VASCULAR; RABBITS; TRANSFECTION; TUNICA INTIMA; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0037458068     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000050652.47145.4C     Document Type: Article

References (17)

1. Kannel W, Gordon T. Cardiovascular risk factors in the aged: the Framingham study. In: Haynes S, Feinleib M, eds. Epidemiology of Aging, Bethesda. Md: National Institutes of Health; 1980:65-98.
2. Weingand KW, Clarkson TB, Adams MR, et al. Effects of age and/or puberty on coronary artery atherosclerosis in cynomolgus monkeys. Atherosclerosis. 1986;62:137-144.
3. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature (London). 1993;362:801-809.
4. Fishman JR, Ryan GB, Karnovsky MJ. Endothelial regeneration in the rat carotid artery and the significance of endothelial denudation in the pathogenesis of myointimal thickening. Lab Invest. 1975;32:339-351.
5. Gerhard M, Roddy MA, Creager SJ, et al. Aging progressively impairs endothelium-dependent vasodilation in forearm resistance vessels of humans. Hypertension. 1996;27:849-853.
6. Zeiher AM, Drexler H, Saurbier B, et al. Endothelium-mediated coronary blood flow modulation in humans: effects of age, atherosclerosis, hypercholesterolemia, and hypertension. J Clin Invest. 1993;92:652-662.
7. Rivard A, Luo Z, Perlman H, et al. Early cell loss after angioplasty results in a disproportionate decrease in percutaneous gene transfer to the vessel wall. Hum Gene Ther. 1999;10:711-721.
8. Asahara T, Chen D, Tsurumi Y. et al. Accelerated restitution of endothelial integrity and endothelium- dependent function after phVEGF165 gene transfer. Circulation. 1996;94:3291-3302.
9. Taddei S, Virdis A, Ghiadoni L, et al. Age-related reduction of NO availability and oxidative stress in humans. Hypertension. 2001;38:274-279.
10. Celermajer DS, Sorensen KE, Georgakopoulos D. et al. Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation. 1993;88:2149-2155.
11. Walker LN, Bowyer DE. Endothelial healing in the rabbit aorta and the effect of risk factors for atherosclerosis. Hypercholesterolemia. Arterioscl. 1984;4:479-488.
12. Sarkar R, Gelabert HA,Mohiuddin KR, et al. Effect of cigarette smoke on endothelial regeneration in vivo and nitric oxide levels. J Surg Res. 1999;82:43-47.
13. Lindner V, Reidy MA. Expression of VEGF receptors in arteries after endothelial injury and lack of increased endothelial regrowth in response to VEGF. Arterioscler Thromb Vasc Biol. 1996;16:1399-1405.
14. Watanabe Y, Lee SW, Detmar M, et al. Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells. Oncogene. 1997;14:2025-2032.
15. Hariri RJ. Hajjar DP, Coletti D, et al. Aging and atherosclerosis: cell cycle kinetics of young and old arterial smooth muscle cells. Am J Pathol. 1988;131:132-136.
16. Asahara T. Murohara T, Sullivan A, et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science. 1997;275:964-967.
17. Waksman R, Bhargava B, Mintz GS, et al. Late total occlusion after intracoronary brachytherapy for patients with in-stent restenosis. J Am Coll Cardiol. 2000;36:65-68.