Diversified world: Drive to life's origin?!

Angewandte Chemie - International Edition

Volumn 42, Issue 3, 2003, Pages 262-266

  Kuhn, Hans ^a   Kuhn, Christoph ^b  

^a Eidgenossische Technische Hochschule ^*  (Switzerland)

^b ETH ZURICH   (Switzerland)

Author keywords

Evolution; Genetic apparatus; Homochirality; Information emergence; Origin of life; Self organization

Indexed keywords

POPULATION STATISTICS;

TEMPORAL-SPATIAL STRUCTURE;

PHYSICAL CHEMISTRY;

BIOGENESIS; CHIRALITY; COMPUTER SIMULATION; EVOLUTION; MOLECULAR GENETICS; MOLECULAR MODEL; REVIEW; STRUCTURE ANALYSIS; THERMODYNAMICS;

BIOGENESIS; EVOLUTION, CHEMICAL; EVOLUTION, MOLECULAR;

EID: 0037455258     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200390098     Document Type: Review

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24. [6] This is of advantage for the start of evolution. Later, when a certain degree of complexity has been achieved that correct fitting together of the components is guaranteed, a more rapidly functioning machine built up from furanosyl-RNA would be more advantageous. But how could such a conversion come about? A genetic apparatus of a certain complexity based upon pyranosyl-RNA produces an enzyme which allows the formation of a furanosyl-RNA replica. This leads to a symbiosis until the furanosyl-RNA based system is no longer dependent upon pyranosyl-RNA system which then disappears.
25. Darwin did not suppose, however, that his theory of the origin of the species is the way to approach the problem of the origin of life, as his famous picture of the start in a "warm little pond", which stimulated the later concept of an primeval soup, shows.
26. M. Eigen, Naturwissenschaften 1971, 58, 465-523; I. Prigogine, D. Glansdorff, Thermodynamic Theory of Structure, Stability and Fluctuations, Wiley-Interscience, New York, 1971.
27. M. Eigen, Naturwissenschaften 1971, 58, 465-523; I. Prigogine, D. Glansdorff, Thermodynamic Theory of Structure, Stability and Fluctuations, Wiley-Interscience, New York, 1971.
28. The frequenly posed question "what first, metabolism or genetic apparatus?" is not relevant in this context. In the given model (life beginning in a most partcular region where chains of reactions lead to a replicating system) the former case is assumed: metabolism present in the beginning, improved and developed during the evolution of the genetic apparatus by stepwise inclusion of enzymes.