7-Chloro-4-methyl-6-nitro-2H-chromen-2-one: A novel type of reagent for fluorescence analysis

Tetrahedron Letters

Volumn 44, Issue 4, 2003, Pages 845-848

  Noe, Christian R ^a   Kornilios, Spyridon ^b   Lachmann, Bodo ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b VIENNA UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

7 CHLORO 4 METHYL 6 NITRO 2H CHROMEN 2 ONE; FLUORESCENT DYE; KETONE DERIVATIVE; NITROGEN DERIVATIVE; PROLINE DERIVATIVE; PYRROLIDINE DERIVATIVE; REAGENT; UNCLASSIFIED DRUG;

AMINATION; ANALYTIC METHOD; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; DERIVATIZATION; FLUORESCENCE ANALYSIS; NITRATION; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION; SUBSTITUTION REACTION; SYNTHESIS; THIN LAYER CHROMATOGRAPHY;

EID: 0037454994     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)02638-2     Document Type: Article

References (24)

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9. 6: (284.6): C, 42.2; H, 1.77; N, 9.84. Found: C, 42.18; H, 1.85; N, 9.48%.
10. 4: (239.62): C, 50.13; H, 2.52; N, 5.85. Found: C, 50.07; H, 2.72; N, 5.88%.
11. 4: (274.28): C, 61.31; H, 5.14; N, 10.21. Found: C, 61.15; H, 5.16; N, 10.32%.
12. Kornilios, S. Diploma Thesis, Technical University of Vienna, 1986.
13. 20: -1354 (c 1.0, DCM).
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16. See: Ref. 3 and references cited therein.
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18. Vacuum-flash-chromatography.
19. 2: (244.29): C, 68.83; H, 6.6; N, 11.47. Found: C, 68.72; H, 6.62; N, 11.41%.
20. 20: +125 (c 1.0, DCM).
21. Fluorescence was measured and quantified at three different wavelengths both for excitation and emission: EX 350/EM 500 nm; EX 350/EM 580 nm; EX 325/EM 520 nm.
22. 20: +37 (c 1.0, toluene).
23. 7-Nitrobenz-2-oxa-1,3-diazole.
24. The compounds 2, 3b and 4b are commercially available from Prochem KFT (prochem@chello.at).