Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 8, 2003, Pages 1487-1490

  Zask, A ^a   Gu, Y ^a   Albright, J D ^a   Du, X ^a   Hogan, M ^a   Levin, J I ^a   Chen, J M ^a   Killar, L M ^a   Sung, A ^a   DiJoseph, J F ^a   Sharr, M A ^a   Roth, C E ^a   Skala, S ^a   Jin, G ^a   Cowling, R ^a   Mohler, K M ^b   Barone, D ^b   Black, R ^b   March, C ^b   Skotnicki, J S ^a  

^a PFIZER INC   (United States)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRANILIC ACID; MATRIX METALLOPROTEINASE INHIBITOR; QUINOLINE; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME INHIBITOR;

ARTICLE; DRUG EFFICACY; DRUG INHIBITION; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; IN VIVO STUDY; OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; STRUCTURE ACTIVITY RELATION;

EID: 0037451823     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00127-6     Document Type: Article

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