Synthesis of 3-arylisocoumarins, including thunberginols A and B, unsymmetrical 3,4-disubstituted isocoumarins, and 3-ylidenephthalides via iodolactonization of methyl 2-ynylbenzoates or the corresponding carboxylic acids

Tetrahedron

Volumn 59, Issue 12, 2003, Pages 2067-2081

  Rossi, Renzo ^a   Carpita, Adriano ^a   Bellina, Fabio ^a   Stabile, Paolo ^a   Mannina, Luisa ^b  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF MOLISE   (Italy)

Author keywords

Cytotoxicity; Iodine; Isocoumarins; Palladium catalysis; Phthalides; Thunberginols

Indexed keywords

3 (3,4 DIMETHOXYPHENYL) 8 METHOXY 4 METHYLISOCOUMARIN; 3 (3,4 DIMETHOXYPHENYL) 8 METHOXYISOCOUMARIN; 3 (4 HYDROXYPHENYL) 6 METHOXYISOCOUMARIN; 4 (1 ETHOXYETHENYL) 3 PHENYLISOCOUMARIN; 4 ACETYL 3 PHENYLISOCOUMARIN; 4 METHYL 3 PHENYLISOCOUMARIN; 6 HYDROXY 3 (4 HYDROXYPHENYL) 4 METHYLISOCOUMARIN; 6 HYDROXY 3 (4 HYDROXYPHENYL)ISOCOUMARIN; 6 METHOXY 3 (4 METHOXYPHENYL) 4 METHYLISOCOUMARIN; 6 METHOXY 3 (4 METHOXYPHENYL)ISOCOUMARIN; 6 METHOXY 3 [4 (3,4,5 TRIMETHOXYBENZOYLOXY)PHENYL]ISOCOUMARIN; 6,8 DIHYDROXY 3 (3,4 DIHYDROXYPHENYL) 4 METHYLISOCOUMARIN; 6,8 DIHYDROXY 3 (3,4 DIHYDROXYPHENYL)ISOCOUMARIN; 6,8 DIMETHOXY 3 (3,4 DIMETHOXYPHENYL) 4 METHYLISOCOUMARIN; 6,8 DIMETHOXY 3 (3,4 DIMETHOXYPHENYL)ISOCOUMARIN; 8 HYDROXY 3 (3,4 DIHYDROXYPHENYL) 4 METHYLISOCOUMARIN; 8 HYDROXY 3 (3,4 DIHYDROXYPHENYL)ISOCOUMARIN; 8 HYDROXY 3 PHENYLISOCOUMARIN; 8 HYDROXY 4 METHYL 3 PHENYLISOCOUMARIN; 8 METHOXY 3 PHENYLISOCOUMARIN; 8 METHOXY 4 METHYL 3 PHENYLISOCOUMARIN; BENZOIC ACID DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; ISOCOUMARIN DERIVATIVE; PHTHALIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IODOLACTONIZATION; PRIORITY JOURNAL; STEREOCHEMISTRY; STEREOSPECIFICITY;

EID: 0037450954     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(03)00212-6     Document Type: Article

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