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Volumn 107, Issue 6, 2003, Pages 798-802

Alterations in Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling in patients with end-stage dilated cardiomyopathy

Author keywords

Cardiomyopathy; Interleukins; Signal transduction

Indexed keywords

CYTOKINE; GLYCOPROTEIN GP 130; INTERLEUKIN 6; JANUS KINASE; LEUKEMIA INHIBITORY FACTOR; RECEPTOR SUBUNIT; STAT PROTEIN; STAT3 PROTEIN;

EID: 0037448803     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000057545.82749.FF     Document Type: Article
Times cited : (127)

References (17)
  • 1
    • 0033592754 scopus 로고    scopus 로고
    • Signaling pathways for cardiac hypertrophy and failure
    • Hunter JJ, Chien KR, Signaling pathways for cardiac hypertrophy and failure. N Engl J Med. 1999;341:1276-1283.
    • (1999) N Engl J Med , vol.341 , pp. 1276-1283
    • Hunter, J.J.1    Chien, K.R.2
  • 2
    • 0033574574 scopus 로고    scopus 로고
    • Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress
    • Hirota H, Chen J, Betz UA, et al. Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Cell. 1999;97:189-198.
    • (1999) Cell , vol.97 , pp. 189-198
    • Hirota, H.1    Chen, J.2    Betz, U.A.3
  • 3
    • 0031041317 scopus 로고    scopus 로고
    • Cardiotrophin-1 inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway
    • Sheng Z, Knowlton K, Chen J, et al. Cardiotrophin-1 inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. J Biol Chem. 1997;272:5783-5791.
    • (1997) J Biol Chem , vol.272 , pp. 5783-5791
    • Sheng, Z.1    Knowlton, K.2    Chen, J.3
  • 4
    • 0034602781 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy
    • Kunisada K, Negoro S, Tone E, et al. Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy. Proc Natl Acad Sci U S A. 2000;97:315-319.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 315-319
    • Kunisada, K.1    Negoro, S.2    Tone, E.3
  • 5
    • 0035964305 scopus 로고    scopus 로고
    • Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase
    • Negoro S, Kunisada K, Fujio Y, et al. Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase. Circulation. 2001;104:979-981.
    • (2001) Circulation , vol.104 , pp. 979-981
    • Negoro, S.1    Kunisada, K.2    Fujio, Y.3
  • 6
    • 0028997843 scopus 로고
    • Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice
    • Hirota H, Yoshida K, Kishimoto T, et al. Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice. Proc Natl Acad Sci U S A. 1995;92:4862-4866.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 4862-4866
    • Hirota, H.1    Yoshida, K.2    Kishimoto, T.3
  • 7
    • 0029933362 scopus 로고    scopus 로고
    • Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy
    • Wollert KC, Taga T, Saito M, et al. Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. J Biol Chem. 1996;271:9535-9545.
    • (1996) J Biol Chem , vol.271 , pp. 9535-9545
    • Wollert, K.C.1    Taga, T.2    Saito, M.3
  • 8
    • 0032575350 scopus 로고    scopus 로고
    • Activation of gp130 transduces hypertrophic signals via STAT3 in cardiac myocytes
    • Kunisada K, Tone E, Fujio Y, et al. Activation of gp130 transduces hypertrophic signals via STAT3 in cardiac myocytes. Circulation. 1998;98:346-352.
    • (1998) Circulation , vol.98 , pp. 346-352
    • Kunisada, K.1    Tone, E.2    Fujio, Y.3
  • 9
    • 0032168152 scopus 로고    scopus 로고
    • Interleukin-6-type cytokine signaling through the gp130/Jak/STAT pathway
    • Heinrich PC, Behrmann I, Muller-Newen G, et al. Interleukin-6-type cytokine signaling through the gp130/Jak/STAT pathway. Biochem J. 1998;334::297-314.
    • (1998) Biochem J , vol.334 , pp. 297-314
    • Heinrich, P.C.1    Behrmann, I.2    Muller-Newen, G.3
  • 10
    • 0035853414 scopus 로고    scopus 로고
    • Induction of JAB/SOCS-1/SSI-1 and CIS3/SOCS-3/SSI-3 is involved in gp130 resistance in cardiovascular system in rat treated with cardiotrophin-1 in vivo
    • Hamanaka I, Saito Y, Yasukawa H, et al. Induction of JAB/SOCS-1/SSI-1 and CIS3/SOCS-3/SSI-3 is involved in gp130 resistance in cardiovascular system in rat treated with cardiotrophin-1 in vivo. Circ Res. 2001;88:727-732.
    • (2001) Circ Res , vol.88 , pp. 727-732
    • Hamanaka, I.1    Saito, Y.2    Yasukawa, H.3
  • 11
    • 0035188432 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-3 is a biomechanical stress-inducible gene that suppresses gp130-mediated cardiac myocyte hypertrophy and survival pathways
    • Yasukawa H, Hoshijima M, Gu Y, et al. Suppressor of cytokine signaling-3 is a biomechanical stress-inducible gene that suppresses gp130-mediated cardiac myocyte hypertrophy and survival pathways. J Clin Invest. 2001;108:1459-1467.
    • (2001) J Clin Invest , vol.108 , pp. 1459-1467
    • Yasukawa, H.1    Hoshijima, M.2    Gu, Y.3
  • 12
    • 0035058586 scopus 로고    scopus 로고
    • The role of interleukin-6 in the failing heart
    • Wollert KC, Drexler H. The role of interleukin-6 in the failing heart. Heart Fail Rev. 2001;6:95-103.
    • (2001) Heart Fail Rev , vol.6 , pp. 95-103
    • Wollert, K.C.1    Drexler, H.2
  • 13
    • 0031977811 scopus 로고    scopus 로고
    • Interleukin-6 spillover in the peripheral circulation increases with the severity of heart failure, and the high plasma level of interleukin-6 is an important prognostic predictor in patients with congestive heart failure
    • Tsutamoto T, Hisanaga T, Wada A, et al. Interleukin-6 spillover in the peripheral circulation increases with the severity of heart failure, and the high plasma level of interleukin-6 is an important prognostic predictor in patients with congestive heart failure. J Am Coll Cardiol. 1998;31:391-398.
    • (1998) J Am Coll Cardiol , vol.31 , pp. 391-398
    • Tsutamoto, T.1    Hisanaga, T.2    Wada, A.3
  • 14
    • 0034082217 scopus 로고    scopus 로고
    • Negative regulation of cytokine signaling pathways
    • Yasukawa H, Sasaki A, Yoshimura A. Negative regulation of cytokine signaling pathways. Annu Rev Immunol. 2000;18:143-164.
    • (2000) Annu Rev Immunol , vol.18 , pp. 143-164
    • Yasukawa, H.1    Sasaki, A.2    Yoshimura, A.3
  • 15
    • 0032498573 scopus 로고    scopus 로고
    • Biphasic activation of the JAK/STAT pathway by angiotensin II in rat cardiomyocytes
    • Kodama H, Fukuda K, Pan J, et al. Biphasic activation of the JAK/STAT pathway by angiotensin II in rat cardiomyocytes. Circ Res. 1998;82:244-250.
    • (1998) Circ Res , vol.82 , pp. 244-250
    • Kodama, H.1    Fukuda, K.2    Pan, J.3
  • 16
    • 0037126009 scopus 로고    scopus 로고
    • Augmented expression of cardiotrophin-1 in failing human hearts is accompanied by diminished glycoprotein 130 receptor protein abundance
    • Zolk O, Ng LL, O'Brien RJ, et al. Augmented expression of cardiotrophin-1 in failing human hearts is accompanied by diminished glycoprotein 130 receptor protein abundance. Circulation. 2002;106:1442-1446.
    • (2002) Circulation , vol.106 , pp. 1442-1446
    • Zolk, O.1    Ng, L.L.2    O'Brien, R.J.3
  • 17
    • 0034616028 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytes
    • Funamoto M, Fujio Y, Kunisada K, et al. Signal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytes. J Biol Chem. 2000;275:10561-10566.
    • (2000) J Biol Chem , vol.275 , pp. 10561-10566
    • Funamoto, M.1    Fujio, Y.2    Kunisada, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.