Development of a method for determination of the malondialdehyde-deoxyguanosine adduct in urine using liquid chromatography-tandem mass spectrometry

Analytical Biochemistry

Volumn 315, Issue 2, 2003, Pages 147-151

  Otteneder, Michael ^a,c   Daniels, J Scott ^b,d   Voehler, Markus ^a   Marnett, Lawrence J ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BAYER AG   (Germany)

^d PFIZER INC   (United States)

Author keywords

DNA adduct; Liquid chromatography mass spectrometry; Malondialdehyde; Pyrimidopurinone

Indexed keywords

AFFINITY CHROMATOGRAPHY; ALDEHYDES; ANTIGEN-ANTIBODY REACTIONS; BIOMOLECULES; CHLORINE COMPOUNDS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; ORGANIC POLYMERS; PHASE SEPARATION; RATS; SODIUM BOROHYDRIDE;

DNA ADDUCTS; IMMUNOAFFINITY CHROMATOGRAPHY; INTERNAL STANDARDS; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MALONDIALDEHYDE; PYRIMIDOPURINONE; SOLID-PHASE EXTRACTION;

GADOLINIUM COMPOUNDS;

CARBON 18; CARBON TETRACHLORIDE; DEOXYGUANOSINE DERIVATIVE; MALONALDEHYDE; PYRIMIDOLE[1,2 ALPHA]PURIN 10(3H) ONE DEOXYRIBOSE; RADIOISOTOPE; SODIUM BOROHYDRIDE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA ADDUCT; IMMUNOAFFINITY CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; URINALYSIS; URINE LEVEL;

EID: 0037446241     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-2697(02)00697-8     Document Type: Article

References (20)

1. Bernheim F., Bernheim M.L.C., Wilbur K.M. J. Biol. Chem. 174:1948;257-264.
2. Hamberg M., Samuelsson B. J. Biol. Chem. 242:1967;5336-5343.
3. Basu A.K., Marnett L.J. Carcinogenesis. 4:1983;331-333.
4. Yau T.M. Mech. Ageing Dev. 11:1979;137-144.
5. J.W. Spalding, NTP technical report 331, 1988, pp. 5-13.
6. Stone K., Ksebati M., Marnett L.J. Chem. Res. Toxicol. 4:1990;33-38.
7. Stone K., Uzieblo A., Marnett L.J. Chem. Res. Toxicol. 4:1990;467-472.
8. Seto H., Okuda T., Takesue T., Ikemura T. Bull. Chem. Soc. Jpn. 56:1983;1799-1802.
9. Chaudhary A.K., Nokubo M., Reddy G.R., Yeola S.N., Morrow J.D., Blair I.A., Marnett L.J. Science. 265:1994;1580-1582.
10. Rouzer C.A., Chaudhary A.K., Nokubo M., Ferguson D.M., Reddy G.R., Blair I.A., Marnett L.J. Chem. Res. Toxicol. 10:1997;181-188.
11. Vaca C.E., Fang J.-L., Mutanen M., Valsta L. Carcinogenesis. 16:1995;1847-1851.
12. Leuratti C., Singh R., Lagneau C., Farmer P.B., Plastaras J.P., Marnett L.J., Shuker D.E. Carcinogenesis. 19:1998;1919-1924.
13. Sharma R.A., Ireson C.R., Verschoyle R.D., Hill K.A., Williams M.L., Leuratti C., Manson M.M., Marnett L.J., Steward W.P., Gescher A. Clin. Cancer Res. 7:2001;1452-1458.
14. Kadlubar F.F., Anderson K.E., Lang N.P., Thompson P.A., MacLeod S.L., Chou M.W., Mikhailova M., Plastaras J., Marnett L.J., Haussermann S., Nair J., Velie I., Bartsch H. Mutat. Res. 405:1998;125-133.
15. Shuker D.E.G., Farmer P.B. Chem. Res. Toxicol. 6:1992;450-460.
16. Schnetz-Boutaud N., Mao H., Stone M.P., Marnett L.J. Chem. Res. Toxicol. 13:2000;90-95.
17. Sevilla C.L., Mahle N.H., Eliezer N., Uzieblo A., O'Hara S.M., Nokubo M., Miller R., Rouzer C.A., Marnett L.J. Chem. Res. Toxicol. 10:1997;172-180.
18. D.E.G. Shuker, P.B. Farmer, in: H. Bartsch, K. Hemminki, I.K. O'Neill (Eds.), Methods for Detecting DNA Damaging Agents in Humans: Applications in Cancer Epidemiology and Prevention, IARC Scientific Publication No. 89, IARC, Lyon, 1988, pp. 92-96.
19. Goda Y., Marnett L.J. Chem. Res. Toxicol. 5:1991;520-524.
20. Jajoo H.K., Burcham P.C., Goda Y., Blair I.A., Marnett L.J. Chem. Res. Toxicol. 6:1992;870-875.