Mutagenesis of the dimer interface residues of tethered and untethered HIV-1 protease result in differential activity and suggest multiple mechanisms of compensation

Virology

Volumn 307, Issue 2, 2003, Pages 204-212

  Choudhury, Sumana ^a   Everitt, Lori ^a   Pettit, Steven C ^a   Kaplan, Andrew H ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Dimer interface; HIV 1 protease; Tethered dimer; Galactosidase

Indexed keywords

MONOMER; PROTEINASE;

AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVITY; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; VIRUS MUTATION;

HOMO; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0037444296     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0042-6822(02)00080-6     Document Type: Article

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