Down-regulation of Notch target gene expression by Suppressor of deltex

Developmental Biology

Volumn 255, Issue 2, 2003, Pages 363-372

  Mazaleyrat, Sabine L ^a,b   Fostier, Maggy ^a   Wilkin, Marian B ^a   Aslam, Hanna ^a,c   Evans, Dana A P ^a   Cornell, Michael ^a   Baron, Martin ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Drosophila; Notch; Suppressor of deltex; Ubiquitin ligase

Indexed keywords

NOTCH RECEPTOR; PROTEIN DERIVATIVE; SU(DX) PROTEIN; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; FORELIMB; GENE CONTROL; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SUPPRESSOR GENE; SUPPRESSOR OF DELTEX GENE;

DROSOPHILA;

EID: 0037443973     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0012-1606(02)00086-6     Document Type: Article

References (40)

1. Artavanis-Tsakonas S., Rand M.D., Lake R.J. Notch signaling Cell fate control and signal integration in development . Science. 284:1999;770-776.
2. Axelrod J.D., Matsuno K., Artavanis-Tsakonas S., Perrimon N. Interaction between Wingless and Notch signaling pathways mediated by Dishevelled. Science. 271:1996;1826-1832.
3. Baonza A., Garcia-Bellido A. Notch signaling directly controls cell proliferation in the Drosophila wing disc. Proc. Natl. Acad. Sci. USA. 97:2000;2609-2614.
4. Baron M., Aslam H., Flasza M., Fostier M., Higgs J.E., Mazaleyrat S.L., Wilkin M.B. Multiple levels of Notch signal regulation. Mol. Membr. Biol. 19:2000;27-38.
5. Bishop S.A., Klein T., Martinez-Arias A., Couso J.P. Composite signalling from Serrate and Delta establishes leg segments in Drosophila through Notch. Development. 126:1999;2993-3003.
6. Brand A., Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development. 118:1993;401-415.
7. Bray S. Notch signalling in Drosophila three ways to use a pathway . Semin. Cell Dev. Biol. 9:1998;591-597.
8. Brennan K., Baylies M., Martinez-Arias A. Repression by Notch is required before Wingless signalling during muscle progenitor cell development in Drosophila. Curr. Biol. 9:1999;707-710.
9. Bruckner K., Perez L., Clausen H., Cohen S. Glycosyltransferase activity of Fringe modulates Notch-Delta interactions. Nature. 406:2000;411-415.
10. Cornell M., Evans D.A., Mann R., Fostier M., Flasza M., Monthatong M., Artavanis-Tsakonas S., Baron M. The Drosophila melanogaster Suppressor of deltex gene, a regulator of the Notch receptor signaling pathway, is an E3 class ubiquitin ligase. Genetics. 152:1999;567-576.
11. de Celis J.F., Bray S.J. The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe. Development. 127:2000;1291-1302.
12. de Celis J.F., Bray S., Garcia-Bellido A. Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing. Development. 124:1997;1919-1928.
13. de Celis J.F., Tyler D.M., de Celis J., Bray S.J. Notch signalling mediates segmentation of the Drosophila leg. Development. 125:1998;4617-4626.
14. Doherty D., Feger G., Younger-Shepherd S., Jan L.Y., Jan Y.N. Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes Dev. 10:1996;421-434.
15. Fostier M., Evans D.A., Artavanis-Tsakonas S., Baron M. Genetic characterization of the Drosophila melanogaster Suppressor of deltex gene a regulator of Notch signaling . Genetics. 150:1998;1477-1485.
16. Guo M., Jan L.Y., Jan Y.N. Control of daughter cell fates during asymmetric division interaction of Numb and Notch . Neuron. 17:1996;27-41.
17. Held L.I., Duarte C.M., Derakhshanian K. Extra tarsal joints and abnormal cuticular polarities in various mutants of Drosophila melanogaster. Roux's Arch. Dev. Biol. 195:1986;145-157.
18. Huibregtse J.M., Scheffner M., Beaudenon S., Howley P.M. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc. Natl. Acad. Sci. USA. 92:1995;2563-2567.
19. Kidd S., Lieber T., Young M.W. Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos. Genes Dev. 12:1998;3728-3740.
20. Klein T., Seugnet L., Haenlin M., Martinez-Arias A. Two different activities of Suppressor of Hairless during wing development in Drosophila. Development. 127:2000;3553-3566.
21. Kopan R., Schroeter E.H., Weintraub H., Nye J.S. Signal transduction by activated mNotch Importance of proteolytic processing and its regulation by the extracellular domain . Proc. Natl. Acad. Sci. USA. 93:1996;1683-1688.
22. Lecourtois M., Schweisguth F. Indirect evidence for Delta-dependent intracellular processing of Notch in Drosophila embryos. Curr Biol. 8:1998;771-774.
23. Lindsley D.L., Zimm G.G. The genome of Drosophila melanogaster. 1992;Academic Press, New York.
24. Matsuno K., Diederich R.J., Go M.J., Blaumueller C.M., Artavanis-Tsakonas S. Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. Development. 121:1995;2633-2644.
25. Matsuno K., Ito M., Hori K., Miyashita F., Suzuki S., Kishi N., Artavanis-Tsakonas S., Okano H. Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling. Development. 129:2002;1049-1059.
26. Mishra A., Agrawal N., Banerjee S., Sardesai D., Dalal J.S., Bhojwani J., Sinha P. Spatial regulation of DELTA expression mediates NOTCH signalling for segmentation of Drosophila legs. Mech. Dev. 105:2001;115-127.
27. Moloney D.J., Panin V.M., Johnston S.H., Chen J., Shao L., Wilson R., Wang Y., Stanley P., Irvine K.D., Haltiwanger R.S., Vogt T.F. Fringe is a glycosyltransferase that modifies Notch. Nature. 406:2000;357-358.
28. Mumm J.S., Kopan R. Notch signaling from the outside in . Dev Biol. 228:2000;151-165.
29. Munro S., Freeman M. The Notch signalling regulator Fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD. Curr. Biol. 10:2000;813-820.
30. Qiu L., Joazeiro C., Fang N., Wang H.Y., Elly C., Altman Y., Fang D., Hunter T., Liu Y.C. Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase. J. Biol. Chem. 275:2000;35734-35737.
31. Ramain P., Khechumian K., Seugnet L., Arbogast N., Ackermann C., Heitzler P. Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate. Curr. Biol. 11:2001;1729-1738.
32. Rauskolb C. The establishment of segmentation in the Drosophila leg. Development. 128:2001;4511-4521.
33. Rauskolb C., Irvine K.D. Notch-mediated segmentation and growth control of the Drosophila leg. Dev. Biol. 210:1999;339-350.
34. Rotin D., Staub O., Haguenauer-Tsapis R. Ubiquitination and endocytosis of plasma membrane proteins role of Nedd4/Rsp5p family of ubiquitin-protein ligases . J. Membr. Biol. 176:2000;1-17.
35. Rulifson E.J., Blair S.S. Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila. Development. 121:1995;2813-2824.
36. Schroeter E.H., Kisslinger J.A., Kopan R. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature. 393:1998;382-386.
37. Smith J.E. 3rd, Cummings C.A., Cronmiller C. daughterless coordinates somatic cell proliferation, differentiation and germline cyst survival during follicle formation in Drosophila. Development. 129:2002;3255-3267.
38. Sturtevant M.A., Bier E. Analysis of the genetic hierarchy guiding wing vein development in Drosophila. Development. 121:1995;785-801.
39. Wesley C.S., Saez L. Notch responds differently to delta and wingless in cultured Drosophila cells. J. Biol. Chem. 275:1999;9099-9101.
40. Williams J.A., Paddock S.W., Vorwerk K., Carroll S.B. Organization of wing formation and induction of a wing-patterning gene at the dorsal/ventral compartment boundary. Nature. 368:1994;299-305.