Fluorobenzo[a]pyrenes as probes of the mechanism of cytochrome P450-catalyzed oxygen transfer in aromatic oxygenations

Free Radical Biology and Medicine

Volumn 34, Issue 6, 2003, Pages 734-745

  Mulder, Patrick P J ^a,c   Devanesan, Prabu ^b   Van Alem, Kaj ^a   Lodder, Gerrit ^a   Rogan, Eleanor G ^b   Cavalieri, Ercole L ^b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Benzo a pyrene radical cation; Cytochrome P450; Fluorobenzo a pyrenes; One electron oxidation; Oxygen transfer; PM3 calculations

Indexed keywords

1 FLUOROBENZO[A]PYRENE; 3 FLUOROBENZO[A]PYRENE; 3 HYDROXYBENZO[A]PYRENE; 6 FLUOROBENZO[A]PYRENE; 6 HYDROXYBENZO[A]PYRENE; AROMATIC COMPOUND; BENZO[A]PYRENE DERIVATIVE; CYTOCHROME P450; HYDROXYBENZO[A]PYRENE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OXYGENATION; PRIORITY JOURNAL; RAT;

EID: 0037443712     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)01374-6     Document Type: Article

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