High-dose glucosamine associated with polyuria and polydipsia in a dog [2]

Journal of the American Veterinary Medical Association

Volumn 222, Issue 4, 2003, Pages 431-432

  McCoy, Sarah J Breese ^a   Bryson, J C ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSAMINE; GLUCOSE;

DOG; DOSE RESPONSE; DRUG ABSORPTION; DRUG HALF LIFE; DRUG MEGADOSE; DRUG URINE LEVEL; HYPERGLYCINEMIA; INSULIN RESISTANCE; LETTER; MALE; NONHUMAN; OSTEOARTHRITIS; POLYDIPSIA; POLYURIA; URINE INCONTINENCE; VETERINARY MEDICINE;

ANIMALS; DOG DISEASES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING; GLUCOSAMINE; OSTEOARTHRITIS; POLYURIA; URINARY INCONTINENCE;

CANIS FAMILIARIS;

EID: 0037442255     PISSN: 00031488     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (6)

1. Echard BW, Talpur NA, Funk KA, et al. Effects of oral glucosamine and chondroitin sulfate alone and in combination on the metabolism of SHR and SD rats. Mol Cell Biochem 2001;225:85-91.
2. Giaccari A. In vivo effects of glucosamine on insulin secretion and insulin sensitivity in the rat: possible relevance to the maladaptive responses to chronic hyperglycaemia. Diabetologia 1995;38:518-524.
3. Shankar R, Zhu JS, Baron AD. Glucosamine infusion in rats mimics the beta-cell dysfunction of non-insulin-dependent diabetes mellitus. Metabolism 1998;47:573-577.
4. Monauni T, Zenti MG, Cretti A, et al. Effects of glucosamine infusion on insulin secretion and insulin action in humans. Diabetes 2000;49:926-935.
5. Chan NN, Osaki R, Chow CC, et al. Drug-related hyperglycemia. JAMA 2002; 287:714-715.
6. Setnikar I, Giachetti C, Zanolo G. Pharmacokinetics of glucosamine in the dog and in man. Arzneimittelforschung 1984;3:538-550.