Encapsulated cell technology could prevent blindness

Drug Discovery Today

Volumn 8, Issue 4, 2003, Pages 146-147

  Burnham, Clyde M ^a  

^a NONE

Author keywords

Cell biology; Drug Discovery; Encapsulated cell technology; Molecular Medicine; Pharmaceutical Science; Photoreceptor cells; Retinal degeneration; Retinitis pigmentosa; Techniques Methods

Indexed keywords

CILIARY NEUROTROPHIC FACTOR;

BIOTECHNOLOGY; BLINDNESS; CELL ENCAPSULATION; CELL MUTANT; CELL SURVIVAL; DISEASE COURSE; DOG; DRUG DELIVERY SYSTEM; HUMAN; INJECTION; LIFE CYCLE; NIGHT BLINDNESS; NONHUMAN; NOTE; PHOTORECEPTOR CELL; PHOTOTRANSDUCTION; RETINITIS PIGMENTOSA; VISUAL FIELD DEFECT;

EID: 0037441483     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(03)02604-7     Document Type: Short Survey

References (4)

1. Tao W., et al. Encapsulated cell-based delivery of CNTF reduces photoreceptor degeneration in animal models of retinitis pigmentosa. Invest. Opthal. Vis. Sci. 43:2002;3292-3298.
2. Dryja T., Li T. Molecular genetics of retinitis pigmentosa. Hum. Mol. Genet. 4:1995;1739-1743.
3. LaVail M., et al. Multiple growth factors, cytokines and neurotrophins rescue photoreceptors from the damaging effects of constant light. Proc. Natl. Acad. Sci. U. S. A. 89:1992;11249-11253.
4. Emerich D., et al. Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease. Nature. 386:1997;395-399.