Effect of metamizol on promyelocytic and terminally differentiated granulocytic cells: Comparative analysis with acetylsalicylic acid and diclofenac

Biochemical Pharmacology

Volumn 65, Issue 2, 2003, Pages 209-217

  García Martínez, José Manuel ^a   Fresno Vara, Juan Ángel ^a   Lastres, Pedro ^b   Bernabéu, Carmelo ^b   Ortiz Betés, Pablo ^c   Martín Pérez, Jorge ^a  

^a INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^c AUTONOMOUS UNIVERSITY OF MADRID   (Spain)

Author keywords

4 Methylaminoantipyrine (MAA); Acetylsalicylic acid (ASA); Dimethyl sulphoxide (DMSO); Granulocytes; Metamizol; Non steroidal anti inflammatory drugs (NSAIDs)

Indexed keywords

ACETYLSALICYLIC ACID; CASPASE; DICLOFENAC; DIMETHYL SULFOXIDE; DIPYRONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NORAMIDOPYRINE;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN HL 60; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG MECHANISM; DRUG RESISTANCE; DRUG SENSITIVITY; ENZYME ACTIVITY; FLOW CYTOMETRY; GRANULOCYTE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMYELOCYTE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; ASPIRIN; CELL DIFFERENTIATION; CELL SURVIVAL; DICLOFENAC; DIMETHYL SULFOXIDE; DIPYRONE; DRUG INTERACTIONS; GRANULOCYTES; HL-60 CELLS; HUMANS;

EID: 0037437727     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)01511-3     Document Type: Article

References (32)

1. Fendrich Z. Metamizol - a new effective analgesic with a long history. Overview of its pharmacology and clinical use. Cas. Lek. Cesk. 139:2000;440-444.
2. Report B. Risks of agranulocytosis and aplastic anemia. A first report of their relation to drug use with special reference to analgesics. The International Agranulocytosis and Aplastic Anemia Study. JAMA. 256:1986;1749-1757.
3. Prieto Alvarez M.P., Fuentes Bellido J.G., Lopez Cebollada J., Escoda Teigell L., Lorenzo Foz J.P. Agranulocytosis caused by metamizol. Anesthetic attitude. Rev. Esp. Anestesiol. Reanim. 45:1998;248-250.
4. Sabbaga J., Osawa C., Pahl F.H., Vellutini E., Pereira D., Cecconello I. Acute agranulocytosis after prolonged high-dose usage of intravenous dipyrone - a different mechanism of dipyrone toxicity? Ann. Hematol. 66:1993;153-155.
5. Bellosillo B., Pique M., Barragan M., Castano E., Villamor N., Colomer D., Montserrat E., Pons G., Gil J. Aspirin and salicylate induce apoptosis and activation of caspases in B-cell chronic lymphocytic leukemia cells. Blood. 92:1998;1406-1414.
6. Chan T.A., Morin P.J., Vogelstein B., Kinzler K.W. Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis. Proc. Natl. Acad. Sci. U.S.A. 95:1998;681-686.
7. Lu X., Xie W., Reed D., Bradshaw W.S., Simmons D.L. Nonsteroidal antiinflammatory drugs cause apoptosis and induce cyclooxygenases in chicken embryo fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 92:1995;7961-7965.
8. Shiff S.J., Qiao L., Tsai L.L., Rigas B. Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells. J. Clin. Invest. 96:1995;491-503.
9. Campos C., de Gregorio R., Garcia-Nieto R., Gago F., Ortiz P., Alemany S. Regulation of cyclooxygenase activity by metamizol. Eur. J. Pharmacol. 378:1999;339-347.
10. Mitchell J.A., Akarasereenont P., Thiemermann C., Flower R.J., Vane J.R. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc. Natl. Acad. Sci. U.S.A. 90:1993;11693-11697.
11. Yaksh T.L., Dirig D.M., Malmberg A.B. Mechanism of action of nonsteroidal anti-inflammatory drugs. Cancer Invest. 16:1998;509-527.
12. Marquez J.A., Pardo C., Amutio E., Cortes C., Pinan M.A., Alvarez C. Drug-induced agranulocytosis: clinical study of 19 cases. Sangre. 43:1998;436-438.
13. Shapiro S., Issaragrisil S., Kaufman D.W., Anderson T., Chansung K., Thamprasit T., Sirijirachai J., Piankijagum A., Porapakkham Y., Vannasaeng S., Leaverton P.E., Young N.S. Agranulocytosis in Bangkok, Thailand: a predominantly drug-induced disease with an unusually low incidence. Aplastic Anemia Study Group. Am. J. Trop. Med. Hyg. 60:1999;573-577.
14. van der Klauw M.M., Goudsmit R., Halie M.R., van't Veer M.B., Herings R.M., Wilson J.H., Stricker B.H. A population-based case-cohort study of drug-associated agranulocytosis. Arch. Intern. Med. 159:1999;369-374.
15. Collins S.J., Ruscetti F.W., Gallagher R.E., Gallo R.C. Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds. Proc. Natl. Acad. Sci. U.S.A. 75:1978;2458-2462.
16. Buzzi M., Lu L., Lombardi A.J. Jr., Posner M.R., Brautigan D.L., Fast L.D., Frackelton A.R. Jr. Differentiation-induced changes in protein-tyrosine phosphatase activity and commensurate expression of CD45 in human leukemia cell lines. Cancer Res. 52:1992;4027-4035.
17. Gee C.E., Griffin J., Sastre L., Miller L.J., Springer T.A., Piwnica-Worms H., Roberts T.M. Differentiation of myeloid cells is accompanied by increased levels of pp60c-src protein and kinase activity. Proc. Natl. Acad. Sci. U.S.A. 83:1986;5131-5135.
18. Boss M.A., Delia D., Robinson J.B., Greaves M.F. Differentiation-linked expression of cell surface markers on HL-60 leukemic cells. Blood. 56:1980;910-916.
19. Ferrero D., Pessano S., Pagliardi G.L., Rovera G. Induction of differentiation of human myeloid leukemias: surface changes probed with monoclonal antibodies. Blood. 61:1983;171-179.
20. Keizer G.D., Borst J., Figdor C.G., Spits H., Miedema F., Terhorst C., De Vries J.E. Biochemical and functional characteristics of the human leukocyte membrane antigen family LFA-1, Mo-1 and p150,95. Eur. J. Immunol. 15:1985;1142-1148.
21. Cabanas C., Sanchez-Madrid F., Acevedo A., Bellon T., Fernandez J.M., Larraga V., Bernabeu C. Characterization of a CD11c-reactive monoclonal antibody (HC1/1) obtained by immunizing with phorbol ester differentiated U937 cells. Hybridoma. 7:1988;167-176.
22. Levy M., Zylber-Katz E., Rosenkranz B. Clinical pharmacokinetics of dipyrone and its metabolites. Clin. Pharmacokinet. 28:1995;216-234.
23. Raschka C., Koch H.J. Pharmacokinetics after oral and intravenous administration of D,L-monolysine acetylsalicylate and an oral dose of acetylsalicylic acid in healthy volunteers. Therapie. 56:2001;669-674.
24. Braunwald E, Fausi AS, Kasper DL, Hauser SL, Longo DL, Jameson JL, editors. Harrison's Principles of Internal Medicine. 15th Ed. New York: McGraw-Hill; 2001, p. 2614-5.
25. Gilman AG, Hardman JG, Limbird LE, editors. Goodman & Gilman. The pharmacological basis of therapeutics. 10th Ed. New York: McGraw-Hill; 2001, p. 696-710.
26. Boyum A. Separation of blood leucocytes, granulocytes and lymphocytes. Tissue Antigens. 4:1974;269-274.
27. Nicoletti I., Migliorati G., Pagliacci M.C., Grignani F., Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods. 139:1991;271-279.
28. Liu Q., Schacher D., Hurth C., Freund G.G., Dantzer R., Kelley K.W. Activation of phosphatidylinositol 3′-kinase by insulin-like growth factor-I rescues promyeloid cells from apoptosis and permits their differentiation into granulocytes. J. Immunol. 159:1997;829-837.
29. Datta R., Kojima H., Banach D., Bump N.J., Talanian R.V., Alnemri E.S., Weichselbaum R.R., Wong W.W., Kufe D.W. Activation of a CrmA-insensitive, p35-sensitive pathway in ionizing radiation-induced apoptosis. J. Biol. Chem. 272:1997;1965-1969.
30. Lazebnik Y.A., Kaufmann S.H., Desnoyers S., Poirier G.G., Earnshaw W.C. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature. 371:1994;346-347.
31. Thornberry N.A., Lazebnik Y. Caspases: enemies within. Science. 281:1998;1312-1316.
32. Rahman M.A., Dhar D.K., Masunaga R., Yamanoi A., Kohno H., Nagasue N. Sulindac and exisulind exhibit a significant antiproliferative effect and induce apoptosis in human hepatocellular carcinoma cell lines. Cancer Res. 60:2000;2085-2089.