Enhanced schistosomicidal efficacy of tartar emetic encapsulated in pegylated liposomes

International Journal of Pharmaceutics

Volumn 255, Issue 1-2, 2003, Pages 227-230

  De Melo, Alan L ^a   Silva Barcellos, Neila M ^a,b   Demicheli, Cynthia ^a   Frézard, Frédéric ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FEDERAL UNIVERSITY OF OURO PRETO   (Brazil)

Author keywords

Antimony; Liposomes; Schistosoma mansoni; Schistosomiasis; Tartar emetic

Indexed keywords

ANTIMONY TARTRATE; LIPOSOME;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; ENCAPSULATION; MALE; MOUSE; NONHUMAN; PARASITOSIS; PRIORITY JOURNAL; SCHISTOSOMA MANSONI; SURVIVAL; TOXICITY; WORM INFECTION;

EID: 0037436994     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(03)00125-X     Document Type: Article

References (15)

1. Allen T.M., Hansen C.B., Guo L.S.S. Subcutaneous administration of liposomes - a comparison with the intravenous and intraperitoneal routes of injection. Biochim. Biophys. Acta. 1150:1993;9-16.
2. Ammar H.O., El-Ridy M.S., Ghorab M., Ghorab M.M. Evaluation of the antischistosomal effect of praziquantel in a liposomal delivery system in mice. Int. J. Pharm. 103:1994;237-241.
3. Appleton C.C., Mbaye A. Praziquantel - quality, dosages and markers of resistance. Trends Parasitol. 17:2001;356-357.
4. Cioli D., Pica-Mattoccia L., Archer S. Antischistosomal drugs: past, present ... and future? Pharm. Ther. 68:1995;35-85.
5. El-Ridy M., Akbarieh M., Kassem M., Sharkawi M., Tawashi R. Chemoprophylaxis of schistosomiasis using liposome-encapsulated tartar emetic. Int. J. Pharm. 56:1989;23-27.
6. Frézard F. Liposomes: from biophysics to the design of peptide vaccines. Braz. J. Med. Biol. Res. 32:1999;181-189.
7. Frézard F., Melo A.L. Evaluation of the schistosomicidal efficacy of liposome-entrapped oxamniquine. Rev. Inst. Med. Trop. São Paulo. 39:1997;97-100.
8. Frézard F., Demicheli C., Ferreira C.S., Costa M.A.P. Glutathione-induced conversion of pentavalent antimony to trivalent antimony in meglumine antimoniate. Antimicrob. Agents Chemother. 45:2001;913-916.
9. Mayer L.D., Hope M.J., Cullis P.R., Janoff A.S. Solute distributions and trapping efficiencies observed in freeze-thawed multilamellar vesicles. Biochim. Biophys. Acta. 817:1985;193-196.
10. Melo A.L., Pereira L.H. Kinetics of the cercaria schistosomulum transformation in vivo. 2. The effect of oxamniquine. Rev. Soc. Bras. Med. Trop. 18:1985;251-255.
11. Melo A.L., Silva-Barcellos N.M., Demicheli C., Frézard F. Schistosomicidal activity of oxamniquine encapsulated in sterically stabilized liposomes. J. Bras. Patol. 37:2001;171-173.
12. Nayar R., Hope M.J., Cullis P.R. Generation of large unilamellar vesicles from long-chain saturated phosphatidylcholines by extrusion technique. Biochim. Biophys. Acta. 986:1989;200-206.
13. Ness A.T., Brady F.J., Cowie D.B., Lawton A.H. Anomalous distribution of antimony in white rats following the administration of tartar emetic. J. Pharmacol. Exp. Ther. 90:1947;174-180.
14. Sturrock R.F. Schistosomiasis epidemiology and control: how did we get here and where should we go? Mem. Inst. Oswaldo Cruz. 96(Suppl.):2001;17-27.
15. Woodle M.C., Lasic D.D. Sterically stabilized liposomes. Biochim. Biophys. Acta. 1113:1992;171-199.