메뉴 건너뛰기




Volumn 141, Issue 1-2, 2003, Pages 71-81

Methylmercury decreases NGF-induced TrkA autophosphorylation and neurite outgrowth in PC12 cells

Author keywords

Methylmercury; Neurite outgrowth; PC12 cell; TrkA

Indexed keywords

ANTIBODY; IODINE 125; METHYLMERCURY; NERVE GROWTH FACTOR; PROTEIN TYROSINE KINASE INHIBITOR; RECEPTOR SUBTYPE; TYROSINE KINASE RECEPTOR;

EID: 0037436524     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(02)00644-2     Document Type: Article
Times cited : (62)

References (84)
  • 3
    • 0028090302 scopus 로고
    • The Trk family of neurotrophin receptors
    • Barbacid M. The Trk family of neurotrophin receptors. J. Neurobiol. 25:1994;1386-1403.
    • (1994) J. Neurobiol. , vol.25 , pp. 1386-1403
    • Barbacid, M.1
  • 4
    • 0024677597 scopus 로고
    • Trophic factors and neuronal survival
    • Barde Y.A. Trophic factors and neuronal survival. Neuron. 2:1989;1525-1534.
    • (1989) Neuron , vol.2 , pp. 1525-1534
    • Barde, Y.A.1
  • 5
    • 0344588827 scopus 로고    scopus 로고
    • Gestational exposure to methylmercury alters the developmental pattern of trk-like immunoreactivity in the rat brain and results in cortical dysmorphology
    • Barone S. Jr., Haykal-Coates N., Parran D.K., Tilson H.A. Gestational exposure to methylmercury alters the developmental pattern of trk-like immunoreactivity in the rat brain and results in cortical dysmorphology. Brain Res. Dev. Brain Res. 109:1998;13-31.
    • (1998) Brain Res. Dev. Brain Res. , vol.109 , pp. 13-31
    • Barone S., Jr.1    Haykal-Coates, N.2    Parran, D.K.3    Tilson, H.A.4
  • 6
    • 0026512998 scopus 로고
    • K-252a inhibits nerve growth factor-induced trk proto-oncogene tyrosine phosphorylation and kinase activity
    • Berg M.M., Sternberg D.W., Parada L.F., Chao M.V. K-252a inhibits nerve growth factor-induced trk proto-oncogene tyrosine phosphorylation and kinase activity. J. Biol. Chem. 267:1992;13-16.
    • (1992) J. Biol. Chem. , vol.267 , pp. 13-16
    • Berg, M.M.1    Sternberg, D.W.2    Parada, L.F.3    Chao, M.V.4
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 0025000941 scopus 로고
    • Methylmercury developmental neurotoxicity: A comparison of effects in humans and animals
    • Burbacher T.M., Rodier P.M., Weiss B. Methylmercury developmental neurotoxicity: a comparison of effects in humans and animals. Neurotoxicol. Teratol. 12:1990;191-202.
    • (1990) Neurotoxicol. Teratol. , vol.12 , pp. 191-202
    • Burbacher, T.M.1    Rodier, P.M.2    Weiss, B.3
  • 9
    • 0017584939 scopus 로고
    • Neurotoxic effects of mercury - A review
    • Chang L.W. Neurotoxic effects of mercury - a review. Environ. Res. 14:1977;329-373.
    • (1977) Environ. Res. , vol.14 , pp. 329-373
    • Chang, L.W.1
  • 10
    • 0026730310 scopus 로고
    • Neurotrophin receptors: A window into neuronal differentiation
    • Chao M.V. Neurotrophin receptors: a window into neuronal differentiation. Neuron. 9:1992;583-593.
    • (1992) Neuron , vol.9 , pp. 583-593
    • Chao, M.V.1
  • 11
    • 0018256847 scopus 로고
    • Abnormal neuronal migration, deranged cerebral cortical organization, and diffuse white matter astrocytosis of human fetal brain: A major effect of methylmercury poisoning in utero
    • Choi B.H., Lapham L.W., Amin-Zaki L., Saleem T. Abnormal neuronal migration, deranged cerebral cortical organization, and diffuse white matter astrocytosis of human fetal brain: a major effect of methylmercury poisoning in utero. J. Neuropathol. Exp. Neurol. 37:1978;719-733.
    • (1978) J. Neuropathol. Exp. Neurol. , vol.37 , pp. 719-733
    • Choi, B.H.1    Lapham, L.W.2    Amin-Zaki, L.3    Saleem, T.4
  • 12
  • 14
    • 0032438305 scopus 로고    scopus 로고
    • Influence of prenatal mercury exposure upon scholastic and psychological test performance: Benchmark analysis of a New Zealand cohort
    • Crump K.S., Kjellstrom T., Shipp A.M., Silvers A., Stewart A. Influence of prenatal mercury exposure upon scholastic and psychological test performance: benchmark analysis of a New Zealand cohort. Risk Anal. 18:1998;701-713.
    • (1998) Risk Anal. , vol.18 , pp. 701-713
    • Crump, K.S.1    Kjellstrom, T.2    Shipp, A.M.3    Silvers, A.4    Stewart, A.5
  • 15
    • 0030991784 scopus 로고    scopus 로고
    • Autophosphorylation of activation loop tyrosines regulates signaling by the TRK nerve growth factor receptor
    • Cunningham M.E., Stephens R.M., Kaplan D.R., Greene L.A. Autophosphorylation of activation loop tyrosines regulates signaling by the TRK nerve growth factor receptor. J. Biol. Chem. 272:1997;10957-10967.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10957-10967
    • Cunningham, M.E.1    Stephens, R.M.2    Kaplan, D.R.3    Greene, L.A.4
  • 17
    • 0027945831 scopus 로고
    • The role of neurotrophins in the developing nervous system
    • Davies A.M. The role of neurotrophins in the developing nervous system. J. Neurobiol. 25:1994;1334-1348.
    • (1994) J. Neurobiol. , vol.25 , pp. 1334-1348
    • Davies, A.M.1
  • 19
    • 0028485768 scopus 로고
    • PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation
    • Dikic I., Schlessinger J., Lax I. PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation. Curr. Biol. 4:1994;702-708.
    • (1994) Curr. Biol. , vol.4 , pp. 702-708
    • Dikic, I.1    Schlessinger, J.2    Lax, I.3
  • 20
    • 0034078796 scopus 로고    scopus 로고
    • Methylmercury exposure affects motor performance of a riverine population of the Tapajos river Brazilian Amazon
    • Dolbec J., Mergler D., Sousa Passos C.J., Sousa D.M., Lebel J. Methylmercury exposure affects motor performance of a riverine population of the Tapajos river Brazilian Amazon. Int. Arch. Occup. Environ. Health. 73:2000;195-203.
    • (2000) Int. Arch. Occup. Environ. Health , vol.73 , pp. 195-203
    • Dolbec, J.1    Mergler, D.2    Sousa Passos, C.J.3    Sousa, D.M.4    Lebel, J.5
  • 21
    • 0024550673 scopus 로고
    • Regulation of the differentiation of PC12 pheochromocytoma cells
    • Fujita K., Lazarovici P., Guroff G. Regulation of the differentiation of PC12 pheochromocytoma cells. Environ. Health Perspect. 80:1989;127-142.
    • (1989) Environ. Health Perspect. , vol.80 , pp. 127-142
    • Fujita, K.1    Lazarovici, P.2    Guroff, G.3
  • 22
    • 0033611497 scopus 로고    scopus 로고
    • In vivo regulation of axon extension and pathfinding by growth-cone calcium transients
    • Gomez T.M., Spitzer N.C. In vivo regulation of axon extension and pathfinding by growth-cone calcium transients. Nature. 397:1999;350-355.
    • (1999) Nature , vol.397 , pp. 350-355
    • Gomez, T.M.1    Spitzer, N.C.2
  • 23
    • 0032076668 scopus 로고    scopus 로고
    • Cognitive performance of children prenatally exposed to 'safe' levels of methylmercury
    • Grandjean P., Weihe P., White R.F., Debes F. Cognitive performance of children prenatally exposed to 'safe' levels of methylmercury. Environ. Res. 77:1998;165-172.
    • (1998) Environ. Res. , vol.77 , pp. 165-172
    • Grandjean, P.1    Weihe, P.2    White, R.F.3    Debes, F.4
  • 24
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Greene L.A., Tischler A.S. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA. 73:1976;2424-2428.
    • (1976) Proc. Natl. Acad. Sci. USA , vol.73 , pp. 2424-2428
    • Greene, L.A.1    Tischler, A.S.2
  • 26
    • 0024094842 scopus 로고
    • K-252a, a potent protein kinase inhibitor, blocks nerve growth factor-induced neurite outgrowth and changes in the phosphorylation of proteins in PC12h cells
    • Hashimoto S. K-252a, a potent protein kinase inhibitor, blocks nerve growth factor-induced neurite outgrowth and changes in the phosphorylation of proteins in PC12h cells. J. Cell Biol. 107:1988;1531-1539.
    • (1988) J. Cell Biol. , vol.107 , pp. 1531-1539
    • Hashimoto, S.1
  • 27
    • 0035395598 scopus 로고    scopus 로고
    • Inhibition of axonal morphogenesis by nonlethal, submicromolar concentrations of methylmercury
    • Heidemann S.R., Lamoureux P., Atchison W.D. Inhibition of axonal morphogenesis by nonlethal, submicromolar concentrations of methylmercury. Toxicol. Appl. Pharmacol. 174:2001;49-59.
    • (2001) Toxicol. Appl. Pharmacol. , vol.174 , pp. 49-59
    • Heidemann, S.R.1    Lamoureux, P.2    Atchison, W.D.3
  • 28
    • 0026468503 scopus 로고
    • Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation
    • Hempstead B.L., Rabin S.J., Kaplan L., Reid S., Parada L.F., Kaplan D.R. Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation. Neuron. 9:1992;883-896.
    • (1992) Neuron , vol.9 , pp. 883-896
    • Hempstead, B.L.1    Rabin, S.J.2    Kaplan, L.3    Reid, S.4    Parada, L.F.5    Kaplan, D.R.6
  • 29
    • 0034046587 scopus 로고    scopus 로고
    • Syntaxin 13 is a developmentally regulated SNARE involved in neurite outgrowth and endosomal trafficking
    • Hirling H., Steiner P., Chaperon C., Marsault R., Regazzi R., Catsicas S. Syntaxin 13 is a developmentally regulated SNARE involved in neurite outgrowth and endosomal trafficking. Eur. J. Neurosci. 12:2000;1913-1923.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 1913-1923
    • Hirling, H.1    Steiner, P.2    Chaperon, C.3    Marsault, R.4    Regazzi, R.5    Catsicas, S.6
  • 30
    • 0027049412 scopus 로고
    • Different ability in PC12 clones to recover from MMC toxicity following NGF treatment
    • Iizuka H., Umeda M. Different ability in PC12 clones to recover from MMC toxicity following NGF treatment. Brain Res. 599:1992;1-5.
    • (1992) Brain Res. , vol.599 , pp. 1-5
    • Iizuka, H.1    Umeda, M.2
  • 31
    • 0023943201 scopus 로고
    • Action of mercurials on activity of partially purified soluble protein kinase C from mice brain
    • Inoue Y., Saijoh K., Sumino K. Action of mercurials on activity of partially purified soluble protein kinase C from mice brain. Pharmacol. Toxicol. 62:1988;278-281.
    • (1988) Pharmacol. Toxicol. , vol.62 , pp. 278-281
    • Inoue, Y.1    Saijoh, K.2    Sumino, K.3
  • 32
  • 33
    • 0035809917 scopus 로고    scopus 로고
    • Protein kinase C activation promotes microtubule advance in neuronal growth cones by increasing average microtubule growth lifetimes
    • Kabir N., Schaefer A.W., Nakhost A., Sossin W.S., Forscher P. Protein kinase C activation promotes microtubule advance in neuronal growth cones by increasing average microtubule growth lifetimes. J. Cell Biol. 152:2001;1033-1044.
    • (2001) J. Cell Biol. , vol.152 , pp. 1033-1044
    • Kabir, N.1    Schaefer, A.W.2    Nakhost, A.3    Sossin, W.S.4    Forscher, P.5
  • 34
    • 0035947724 scopus 로고    scopus 로고
    • Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells
    • Kao S., Jaiswal R.K., Kolch W., Landreth G.E. Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells. J. Biol. Chem. 276:2001;18169-18177.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18169-18177
    • Kao, S.1    Jaiswal, R.K.2    Kolch, W.3    Landreth, G.E.4
  • 35
    • 0025797396 scopus 로고
    • Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF
    • Kaplan D.R., Martin-Zanca D., Parada L.F. Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF. Nature. 350:1991;158-160.
    • (1991) Nature , vol.350 , pp. 158-160
    • Kaplan, D.R.1    Martin-Zanca, D.2    Parada, L.F.3
  • 37
    • 0023616449 scopus 로고
    • Depolarization-induced increase in surface binding and internalization of 125I-nerve growth factor by PC12 pheochromocytoma cells
    • Koike T. Depolarization-induced increase in surface binding and internalization of 125I-nerve growth factor by PC12 pheochromocytoma cells. J. Neurochem. 49:1987;1784-1789.
    • (1987) J. Neurochem. , vol.49 , pp. 1784-1789
    • Koike, T.1
  • 39
    • 0027195615 scopus 로고
    • The neurotrophic factor concept: A reexamination
    • Korsching S. The neurotrophic factor concept: a reexamination. J. Neurosci. 13:1993;2739-2748.
    • (1993) J. Neurosci. , vol.13 , pp. 2739-2748
    • Korsching, S.1
  • 40
    • 0030909239 scopus 로고    scopus 로고
    • Migration of granule neurons in cerebellar organotypic cultures is impaired by methylmercury
    • Kunimoto M., Suzuki T. Migration of granule neurons in cerebellar organotypic cultures is impaired by methylmercury. Neurosci. Lett. 226:1997;183-186.
    • (1997) Neurosci. Lett. , vol.226 , pp. 183-186
    • Kunimoto, M.1    Suzuki, T.2
  • 41
    • 0019052563 scopus 로고
    • Nerve growth factor receptors on PC12 cells: Ligand-induced conversion from low- to high-affinity states
    • Landreth G.E., Shooter E.M. Nerve growth factor receptors on PC12 cells: ligand-induced conversion from low- to high-affinity states. Proc. Natl. Acad. Sci. USA. 77:1980;4751-4755.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 4751-4755
    • Landreth, G.E.1    Shooter, E.M.2
  • 42
    • 0026055076 scopus 로고
    • Methylmercury induced alterations in the nerve growth factor level in the developing brain
    • Larkfors L., Oskarsson A., Sundberg J., Ebendal T. Methylmercury induced alterations in the nerve growth factor level in the developing brain. Brain Res. Dev. Brain Res. 62:1991;287-291.
    • (1991) Brain Res. Dev. Brain Res. , vol.62 , pp. 287-291
    • Larkfors, L.1    Oskarsson, A.2    Sundberg, J.3    Ebendal, T.4
  • 44
    • 0026091934 scopus 로고
    • The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines
    • Loeb D.M., Maragos J., Martin-Zanca D., Chao M.V., Parada L.F., Greene L.A. The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines. Cell. 66:1991;961-966.
    • (1991) Cell , vol.66 , pp. 961-966
    • Loeb, D.M.1    Maragos, J.2    Martin-Zanca, D.3    Chao, M.V.4    Parada, L.F.5    Greene, L.A.6
  • 45
    • 0028245830 scopus 로고
    • A Trk nerve growth factor (NGF) receptor point mutation affecting interaction with phospholipase C-gamma 1 abolishes NGF-promoted peripherin induction but not neurite outgrowth
    • Loeb D.M., Stephens R.M., Copeland T., Kaplan D.R., Greene L.A. A Trk nerve growth factor (NGF) receptor point mutation affecting interaction with phospholipase C-gamma 1 abolishes NGF-promoted peripherin induction but not neurite outgrowth. J. Biol. Chem. 269:1994;8901-8910.
    • (1994) J. Biol. Chem. , vol.269 , pp. 8901-8910
    • Loeb, D.M.1    Stephens, R.M.2    Copeland, T.3    Kaplan, D.R.4    Greene, L.A.5
  • 46
    • 0031773454 scopus 로고    scopus 로고
    • Prenatal and lactational exposure to methylmercury affects select parameters of mouse cerebellar development
    • Markowski V.P., Flaugher C.B., Baggs R.B., Rawleigh R.C., Cox C., Weiss B. Prenatal and lactational exposure to methylmercury affects select parameters of mouse cerebellar development. Neurotoxicology. 19:1998;879-892.
    • (1998) Neurotoxicology , vol.19 , pp. 879-892
    • Markowski, V.P.1    Flaugher, C.B.2    Baggs, R.B.3    Rawleigh, R.C.4    Cox, C.5    Weiss, B.6
  • 47
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall C.J. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell. 80:1995;179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 49
    • 0000185397 scopus 로고
    • Fetal Minamata disease. A neuropathological study of two cases of intrauterine intoxication by a methyl mercury compound
    • Matsumoto H., Koya G., Takeuchi T. Fetal Minamata disease. A neuropathological study of two cases of intrauterine intoxication by a methyl mercury compound. J. Neuropathol. Exp. Neurol. 24:1965;563-574.
    • (1965) J. Neuropathol. Exp. Neurol. , vol.24 , pp. 563-574
    • Matsumoto, H.1    Koya, G.2    Takeuchi, T.3
  • 50
    • 0025986121 scopus 로고
    • New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
    • McDonald N.Q., Lapatto R., Murray-Rust J., Gunning J., Wlodawer A., Blundell T.L. New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor. Nature. 354:1991;411-414.
    • (1991) Nature , vol.354 , pp. 411-414
    • McDonald, N.Q.1    Lapatto, R.2    Murray-Rust, J.3    Gunning, J.4    Wlodawer, A.5    Blundell, T.L.6
  • 51
    • 0034875314 scopus 로고    scopus 로고
    • Neurotrophin signalling pathways regulating neuronal apoptosis
    • Miller F.D., Kaplan D.R. Neurotrophin signalling pathways regulating neuronal apoptosis. Cell Mol. Life Sci. 58:2001;1045-1053.
    • (2001) Cell Mol. Life Sci. , vol.58 , pp. 1045-1053
    • Miller, F.D.1    Kaplan, D.R.2
  • 52
    • 0002850064 scopus 로고
    • The pathological lesions of methyl mercury intoxication in monkeys
    • C.U. Eccles, & Z. Annau. Baltimore, MD: The Johns Hopkins University Press
    • Mottet N.K., Shaw C., Burbacher T.M. The pathological lesions of methyl mercury intoxication in monkeys. Eccles C.U., Annau Z. The Toxicity of Methyl Mercury. 1987;73-103 The Johns Hopkins University Press, Baltimore, MD.
    • (1987) The Toxicity of Methyl Mercury , pp. 73-103
    • Mottet, N.K.1    Shaw, C.2    Burbacher, T.M.3
  • 53
    • 0001248942 scopus 로고    scopus 로고
    • Gestational exposure to methylmercury alters the developmental pattern of neurotrophin- and neurotransmitter-induced phosphoinositide (PI) hydrolysis
    • Mundy W.R., Parran D.K., Barone S. Jr. Gestational exposure to methylmercury alters the developmental pattern of neurotrophin- and neurotransmitter-induced phosphoinositide (PI) hydrolysis. Neurotoxicity Res. 1:2000;271-283.
    • (2000) Neurotoxicity Res. , vol.1 , pp. 271-283
    • Mundy, W.R.1    Parran, D.K.2    Barone S., Jr.3
  • 55
    • 0019732984 scopus 로고
    • Effect of methylmercury and inorganic mercury on the nerve growth factor-induced neurite outgrowth in chick embryonic sensory ganglia
    • Nakada S., Saito H., Imura N. Effect of methylmercury and inorganic mercury on the nerve growth factor-induced neurite outgrowth in chick embryonic sensory ganglia. Toxicol Lett. 8:1981;23-28.
    • (1981) Toxicol Lett. , vol.8 , pp. 23-28
    • Nakada, S.1    Saito, H.2    Imura, N.3
  • 56
    • 0014696840 scopus 로고
    • An electron microscopic study on the experimental congenital Minamata disease in the rat
    • Nonaka I. An electron microscopic study on the experimental congenital Minamata disease in the rat. Kumamoto Med. J. 22:1969;27-40.
    • (1969) Kumamoto Med. J. , vol.22 , pp. 27-40
    • Nonaka, I.1
  • 57
    • 0028293929 scopus 로고
    • Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma
    • Obermeier A., Bradshaw R.A., Seedorf K., Choidas A., Schlessinger J., Ullrich A. Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma. EMBO J. 13:1994;1585-1590.
    • (1994) EMBO J. , vol.13 , pp. 1585-1590
    • Obermeier, A.1    Bradshaw, R.A.2    Seedorf, K.3    Choidas, A.4    Schlessinger, J.5    Ullrich, A.6
  • 58
    • 0026684676 scopus 로고
    • Inhibition of the cellular actions of nerve growth factor by staurosporine and K252A results from the attenuation of the activity of the trk tyrosine kinase
    • Ohmichi M., Decker S.J., Pang L., Saltiel A.R. Inhibition of the cellular actions of nerve growth factor by staurosporine and K252A results from the attenuation of the activity of the trk tyrosine kinase. Biochemistry. 31:1992;4034-4039.
    • (1992) Biochemistry , vol.31 , pp. 4034-4039
    • Ohmichi, M.1    Decker, S.J.2    Pang, L.3    Saltiel, A.R.4
  • 59
    • 0035125134 scopus 로고    scopus 로고
    • Effects of methylmercury and mercuric chloride on differentiation and cell viability in PC12 cells
    • Parran D.K., Mundy W.R., Barone S. Jr. Effects of methylmercury and mercuric chloride on differentiation and cell viability in PC12 cells. Toxicol. Sci. 59:2001;278-290.
    • (2001) Toxicol. Sci. , vol.59 , pp. 278-290
    • Parran, D.K.1    Mundy, W.R.2    Barone S., Jr.3
  • 60
    • 0026338953 scopus 로고
    • NGF and EGF rapidly activate p21ras in PC12 cells by distinct, convergent pathways involving tyrosine phosphorylation
    • Qiu M.S., Green S.H. NGF and EGF rapidly activate p21ras in PC12 cells by distinct, convergent pathways involving tyrosine phosphorylation. Neuron. 7:1991;937-946.
    • (1991) Neuron , vol.7 , pp. 937-946
    • Qiu, M.S.1    Green, S.H.2
  • 62
    • 0018628678 scopus 로고
    • Effects of methylmercury on the development of the nervous system: A review
    • Reuhl K., Chang L.W. Effects of methylmercury on the development of the nervous system: a review. Neurotoxicology. 1:1979;21-55.
    • (1979) Neurotoxicology , vol.1 , pp. 21-55
    • Reuhl, K.1    Chang, L.W.2
  • 63
    • 0019838733 scopus 로고
    • Pathological effects of in utero methylmercury exposure on the cerebellum of the golden hamster. 1. Early effects upon the neonatal cerebellar cortex
    • Reuhl K.R., Chang L.W., Townsend J.W. Pathological effects of in utero methylmercury exposure on the cerebellum of the golden hamster. 1. Early effects upon the neonatal cerebellar cortex. Environ. Res. 26:1981;281-306.
    • (1981) Environ. Res. , vol.26 , pp. 281-306
    • Reuhl, K.R.1    Chang, L.W.2    Townsend, J.W.3
  • 64
    • 0024942011 scopus 로고
    • Delayed neurotoxicity in monkeys exposed developmentally to methylmercury
    • Rice D.C. Delayed neurotoxicity in monkeys exposed developmentally to methylmercury. Neurotoxicology. 10:1989;645-650.
    • (1989) Neurotoxicology , vol.10 , pp. 645-650
    • Rice, D.C.1
  • 65
    • 0021344790 scopus 로고
    • Persistent, differential alterations in developing cerebellar cortex of male and female mice after methylmercury exposure
    • Sager P.R., Aschner M., Rodier P.M. Persistent, differential alterations in developing cerebellar cortex of male and female mice after methylmercury exposure. Brain Res. 314:1984;1-11.
    • (1984) Brain Res. , vol.314 , pp. 1-11
    • Sager, P.R.1    Aschner, M.2    Rodier, P.M.3
  • 67
    • 0019501554 scopus 로고
    • Nerve growth factor receptors on PC12 cells: Evidence for two receptor classes with differing cytoskeletal association
    • Schechter A.L., Bothwell M.A. Nerve growth factor receptors on PC12 cells: evidence for two receptor classes with differing cytoskeletal association. Cell. 24:1981;867-874.
    • (1981) Cell , vol.24 , pp. 867-874
    • Schechter, A.L.1    Bothwell, M.A.2
  • 68
    • 0026009877 scopus 로고
    • A novel modular mosaic of cell adhesion motifs in the extracellular domains of the neurogenic trk and trkB tyrosine kinase receptors
    • Schneider R., Schweiger M. A novel modular mosaic of cell adhesion motifs in the extracellular domains of the neurogenic trk and trkB tyrosine kinase receptors. Oncogene. 6:1991;1807-1811.
    • (1991) Oncogene , vol.6 , pp. 1807-1811
    • Schneider, R.1    Schweiger, M.2
  • 70
    • 0028833720 scopus 로고
    • In vitro toxicity of methyl mercury: Effects on nerve growth factor (NGF)-responsive neurons and on NGF synthesis in fibroblasts
    • Söderström S., Ebendal T. In vitro toxicity of methyl mercury: effects on nerve growth factor (NGF)-responsive neurons and on NGF synthesis in fibroblasts. Toxicol. Lett. 75:1995;133-144.
    • (1995) Toxicol. Lett. , vol.75 , pp. 133-144
    • Söderström, S.1    Ebendal, T.2
  • 71
    • 0024516653 scopus 로고
    • Inhibition of phorbol ester binding and protein kinase C activity by heavy metals
    • Speizer L.A., Watson M.J., Kanter J.R., Brunton L.L. Inhibition of phorbol ester binding and protein kinase C activity by heavy metals. J. Biol. Chem. 264:1989;5581-5585.
    • (1989) J. Biol. Chem. , vol.264 , pp. 5581-5585
    • Speizer, L.A.1    Watson, M.J.2    Kanter, J.R.3    Brunton, L.L.4
  • 72
    • 0028199799 scopus 로고
    • Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses
    • Stephens R.M., Loeb D.M., Copeland T.D., Pawson T., Greene L.A., Kaplan D.R. Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses. Neuron. 12:1994;691-705.
    • (1994) Neuron , vol.12 , pp. 691-705
    • Stephens, R.M.1    Loeb, D.M.2    Copeland, T.D.3    Pawson, T.4    Greene, L.A.5    Kaplan, D.R.6
  • 73
    • 0028360018 scopus 로고
    • Cellular components of nerve growth factor signaling
    • Szeberenyi J., Erhardt P. Cellular components of nerve growth factor signaling. Biochim. Biophys. Acta. 1222:1994;187-202.
    • (1994) Biochim. Biophys. Acta , vol.1222 , pp. 187-202
    • Szeberenyi, J.1    Erhardt, P.2
  • 75
    • 0026563244 scopus 로고
    • K252a is a selective inhibitor of the tyrosine protein kinase activity of the trk family of oncogenes and neurotrophin receptors
    • Tapley P., Lamballe F., Barbacid M. K252a is a selective inhibitor of the tyrosine protein kinase activity of the trk family of oncogenes and neurotrophin receptors. Oncogene. 7:1992;371-381.
    • (1992) Oncogene , vol.7 , pp. 371-381
    • Tapley, P.1    Lamballe, F.2    Barbacid, M.3
  • 76
    • 0025877704 scopus 로고
    • The changing scene of neurotrophic factors
    • Thoenen H. The changing scene of neurotrophic factors. Trends Neurosci. 14:1991;165-170.
    • (1991) Trends Neurosci. , vol.14 , pp. 165-170
    • Thoenen, H.1
  • 77
    • 0026486878 scopus 로고
    • Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor
    • Traverse S., Gomez N., Paterson H., Marshall C., Cohen P. Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. Biochem. J. 288:(Pt 2):1992;351-355.
    • (1992) Biochem. J. , vol.288 , Issue.PART 2 , pp. 351-355
    • Traverse, S.1    Gomez, N.2    Paterson, H.3    Marshall, C.4    Cohen, P.5
  • 78
  • 79
    • 0029971881 scopus 로고    scopus 로고
    • Health implications for Faroe islanders of heavy metals and PCBs from pilot whales
    • Weihe P., Grandjean P., Debes F., White R. Health implications for Faroe islanders of heavy metals and PCBs from pilot whales. Sci. Total Environ. 186:1996;141-148.
    • (1996) Sci. Total Environ. , vol.186 , pp. 141-148
    • Weihe, P.1    Grandjean, P.2    Debes, F.3    White, R.4
  • 80
    • 0034130117 scopus 로고    scopus 로고
    • Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: Relationship to differentiation and survival of PC12 cells
    • Wooten M.W., Seibenhener M.L., Neidigh K.B., Vandenplas M.L. Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: relationship to differentiation and survival of PC12 cells. Mol. Cell. Biol. 20:2000;4494-4504.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4494-4504
    • Wooten, M.W.1    Seibenhener, M.L.2    Neidigh, K.B.3    Vandenplas, M.L.4
  • 81
    • 0027977927 scopus 로고
    • A role for zeta protein kinase C in nerve growth factor-induced differentiation of PC12 cells
    • Wooten M.W., Zhou G., Seibenhener M.L., Coleman E.S. A role for zeta protein kinase C in nerve growth factor-induced differentiation of PC12 cells. Cell Growth Differ. 5:1994;395-403.
    • (1994) Cell Growth Differ. , vol.5 , pp. 395-403
    • Wooten, M.W.1    Zhou, G.2    Seibenhener, M.L.3    Coleman, E.S.4
  • 82
    • 0033776498 scopus 로고    scopus 로고
    • Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1
    • York R.D., Molliver D.C., Grewal S.S., Stenberg P.E., McCleskey E.W., Stork P.J. Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1. Mol. Cell. Biol. 20:2000;8069-8083.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8069-8083
    • York, R.D.1    Molliver, D.C.2    Grewal, S.S.3    Stenberg, P.E.4    McCleskey, E.W.5    Stork, P.J.6
  • 83
    • 0031730287 scopus 로고    scopus 로고
    • Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis
    • Zapf-Colby A., Olefsky J.M. Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis. Endocrinology. 139:1998;3232-3240.
    • (1998) Endocrinology , vol.139 , pp. 3232-3240
    • Zapf-Colby, A.1    Olefsky, J.M.2
  • 84
    • 0029156292 scopus 로고
    • Multiple levels for regulation of TrkA in PC12 cells by nerve growth factor
    • Zhou J., Valletta J.S., Grimes M.L., Mobley W.C. Multiple levels for regulation of TrkA in PC12 cells by nerve growth factor. J. Neurochem. 65:1995;1146-1156.
    • (1995) J. Neurochem. , vol.65 , pp. 1146-1156
    • Zhou, J.1    Valletta, J.S.2    Grimes, M.L.3    Mobley, W.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.